Human ovarian reserve from conception to the menopause

Autor: Wallace, W H B, Kelsey, T W

The human ovary contains a fixed number of non-growing follicles (NGFs) established before birth that decline with increasing age culminating in the menopause at 50-51 years. The objective of this study is to model the age-related population of NGFs

Externí odkaz: http://arxiv.org/abs/1106.1382

Machine Science in Biomedicine: Practicalities, Pitfalls and Potential

Autor: Kelsey, T W, Wallace, W H B

Machine Science, or Data-driven Research, is a new and interesting scientific methodology that uses advanced computational techniques to identify, retrieve, classify and analyse data in order to generate hypotheses and develop models. In this paper w

Externí odkaz: http://arxiv.org/abs/1008.3795

Response-adapted omission of radiotherapy and comparison of consolidation chemotherapy in intermediate- and advanced-stage children and adolescents with classic Hodgkin lymphoma: a titration study with an embedded non-inferiority randomised controlled trial

Autor: Mauz-Körholz, Christine, Landman-Parker, Judith, Balwierz , Walentyna, Ammann , Roland A, Anderson, Richard A, Attarbaschi , Andische, Bartelt, Jörg M, Beishuizen , Auke, Boudjemaa , Sabah, Cepelova , Michaela, Claviez , Alexander, Daw, Stephen, Dieckmann , Karin, Fernández-Teijeiro , Ana, Fosså , Alexander, Gattenlöhner , Stefan, Georgi , Thomas, Hjalgrim, Lisa, Hraskova, Andrea, Karlén , Jonas, Kluge , Regine, Kurch , Lars, Leblanc , Thiery, Mann , Georg, Montravers , Francoise, Pears, Jean, Pelz , Tanja, Rajić, Vladan, Ramsay, Alan, Stoevesandt , Dietrich, Uyttebroeck , Anne, Vordermark, Dirk, Körholz , Dieter, Hasenclever , Dirk, Wallace, W. H. B.

Publikováno v: Mauz-Körholz, C, Landman-Parker, J, Balwierz, W, Ammann, R A, Anderson, R A, Attarbaschi, A, Bartelt, J M, Beishuizen, A, Boudjemaa, S, Cepelova, M, Claviez, A, Daw, S, Dieckmann, K, Fernández-Teijeiro, A, Fosså, A, Gattenlöhner, S, Georgi, T, Hjalgrim, L, Hraskova, A, Karlén, J, Kluge, R, Kurch, L, Leblanc, T, Mann, G, Montravers, F, Pears, J, Pelz, T, Rajić, V, Ramsay, A, Stoevesandt, D, Uyttebroeck, A, Vordermark, D, Körholz, D, Hasenclever, D & Wallace, W H B 2022, ' Response-adapted omission of radiotherapy and comparison of consolidation chemotherapy in intermediate-and advanced-stage children and adolescents with classic Hodgkin lymphoma: a titration study with an embedded non-inferiority randomised controlled trial ', The Lancet Oncology, vol. 23, no. 1, pp. 125-137 . https://doi.org/10.1016/S1470-2045(21)00470-8

BACKGROUND: Children and adolescents with intermediate-stage and advanced-stage classical Hodgkin lymphoma achieve an event-free survival at 5 years of about 90% after treatment with vincristine, etoposide, prednisone, and doxorubicin (OEPA) followed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::8954227ca015f490198c8dfc8012b53b
https://www.pure.ed.ac.uk/ws/files/250522450/PIIS1470204521004708.pdf

Metaphase II oocytes from human unilaminar follicles grown in a multi-step culture system

Autor: McLaughlin, Marie, Albertini, D F, Wallace, W. H. B., Anderson, Richard, Telfer, Evelyn

Publikováno v: McLaughlin, M, Albertini, D F, Wallace, W H B, Anderson, R & Telfer, E 2018, ' Metaphase II oocytes from human unilaminar follicles grown in a multi-step culture system ', Molecular Human Reproduction, vol. 24, no. 3, pp. 135–142 . https://doi.org/10.1093/molehr/gay002

STUDY QUESTION: Can complete oocyte development be achieved from human ovarian tissue containing primordial/unilaminar follicles and grown in vitro in a multi-step culture to meiotic maturation demonstrated by the formation of polar bodies and a Meta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::4f626093550c0db6eb82b795a3194818
https://hdl.handle.net/20.500.11820/55cbb793-3401-4172-80a9-44412ecdf216

Metaphase II oocytes from human unilaminar follicles grown in a multistep culture system.

Autor: McLaughlin, M., Albertini, D. F., Wallace, W. H. B., Anderson, R. A., Telfer, E. E.

Publikováno v: Molecular Human Reproduction; Mar2018, Vol. 24 Issue 3, p135-142, 8p