Zobrazeno 1 - 10
of 371
pro vyhledávání: '"W.W. ten Bokkel Huinink"'
Autor:
Gerard Groenewegen, V. M. M. Herben, Thomas Kerbusch, B Ambaum, Hilde Rosing, Emile E. Voest, M. Swart, Jan H.M. Schellens, Sindy Jansen, Ron A. A. Mathot, Jos H. Beijnen, W.W. ten Bokkel Huinink
Publikováno v:
British Journal of Cancer
British journal of cancer, 90(12), 2268-2277. Nature Publishing Group
British journal of cancer, 90(12), 2268-2277. Nature Publishing Group
To determine the maximum-tolerated dose (MTD), dose-limiting toxicities, and pharmacokinetics of topotecan administered as a 30-min intravenous (i.v.) infusion over 5 days in combination with a 1-h i.v. infusion of ifosfamide (IF) for 3 consecutive d
Autor:
Nadja E. Schoemaker, Sindy Jansen, Jan Lieverst, R Spinelli, Massimo Breda, M. Swart, C Pellizzoni, Hilde Rosing, C. van Kesteren, D Fraier, M Grazia Porro, W.W. ten Bokkel Huinink, Jos H. Beijnen, Jan H.M. Schellens
Publikováno v:
British Journal of Cancer
Polymeric drug conjugates are a new and experimental class of drug delivery systems with pharmacokinetic promises. The antineoplastic drug camptothecin was linked to a water-soluble polymeric backbone (MAG-CPT) and administrated as a 30 min infusion
Autor:
J. Lopez-Pousa, Montserrat Estorch, Otilia Dalesio, R.A. Valdés Olmos, W.W. ten Bokkel Huinink, Cornelis A. Hoefnagel, Ignasi Carrió
Publikováno v:
Nuclear Medicine Communications. 23:871-877
11In antimyosin scintigraphy was evaluated at various cumulative anthracycline dose levels in order to early identify patients with severe cardiac injury and increased long-term risk of cardiac dysfunction. Twenty-four patients receiving standard dos
Autor:
M.J. van de Vijver, Simon Horenblas, J.A. Witjes, T.A. Roeleveld, W.W. ten Bokkel Huinink, H.G. van der Poel, C.A. Hulsbergen-van de Kaa, J.R Spermon
Publikováno v:
Urology, 59, 923-9
Urology, 59(6), 923-929. Elsevier Inc.
Urology, 59, 6, pp. 923-9
Urology, 59(6), 923-929. Elsevier Inc.
Urology, 59, 6, pp. 923-9
Item does not contain fulltext OBJECTIVES: To compare retrospectively the treatment results of surveillance and primary retroperitoneal lymph node dissection (RPLND) of patients with clinical Stage I nonseminomatous germ cell tumors of the testis (NS
Autor:
Hilde Rosing, Jan H.M. Schellens, W.W. ten Bokkel Huinink, Mirte M. Malingré, Heleen A. Bardelmeijer, Koopman Fj, Jos H. Beijnen, Margaret Schot, O. van Tellingen, Mariët Ouwehand
Publikováno v:
British Journal of Cancer
The purpose of this study was to investigate the effect of the co-solvents Cremophor EL and polysorbate 80 on the absorption of orally administered paclitaxel. 6 patients received in a randomized setting, one week apart oral paclitaxel 60 mg m−2 di
Autor:
Mirte M. Malingré, Hilde Rosing, Koopman Fj, Jos H. Beijnen, Jan H.M. Schellens, Elaine M. Paul, W.W. ten Bokkel Huinink, R. C. Jewell
Publikováno v:
British Journal of Cancer
Oral bioavailability of paclitaxel is very low, which is due to efficient transport of the drug by the intestinal drug efflux pump P-glycoprotein (P-gp). We have recently demonstrated that the oral bioavailability of paclitaxel can be increased at le
Autor:
P.J.M. van de Vaart, M. M. Kaag, A.R. van Goethem, W.W. ten Bokkel Huinink, J. H. Beijnen, F.A.N. Zoetmulder, N. van der Vange
Publikováno v:
European Journal of Surgical Oncology. 26:663-668
Aims: The feasibility, morbidity and toxicity of an intensified surgical treatment strategy consisting of aggressive cytoreductive surgery, intra-operative intraperitoneal perfusion of cisplatin and hyperthermia were evaluated in women with recurrent
Autor:
D Fraier, Koopman Fj, E. Frigerio, J. M. Meerum Terwogt, Jan H.M. Schellens, Hilde Rosing, M. Rocchetti, W.W. ten Bokkel Huinink, Jos H. Beijnen
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 23:1233-1251
A high-performance liquid chromatographic (HPLC) assay has been designed for the quantitative determination of polymer-bound paclitaxel (after hydrolytic release of paclitaxel from the polymer) and free paclitaxel in human plasma after intravenous ad
Autor:
R. F. M. Rombouts, Auke Bult, Jos H. Beijnen, R. van Gijn, W.W. ten Bokkel Huinink, Hilde Rosing
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 24:69-77
The purpose of this study was to compare the pharmacokinetic disposition of two intravenous dexrazoxane formulations, and their effects on doxorubicin's kinetics and metabolism. Plasma concentration versus time curves and pharmacokinetic parameters o
Autor:
W.W. ten Bokkel Huinink, Herbert Sindermann, I.A.M. Mandjes, Jos H. Beijnen, Jetske M. Meerum Terwogt
Publikováno v:
British Journal of Cancer
Skin deposits from breast cancer can present serious therapeutic problems, especially when resistant to conventional therapy. Topical application of a cytotoxic drug may represent an attractive new treatment modality devoid of major systemic toxicity