Zobrazeno 1 - 10
of 24
pro vyhledávání: '"W.W. Wolstenholme"'
Autor:
E.H. Fernández, Hugo F. Miranda, N. Cuevas, D. Bustamante, W.W. Wolstenholme, W.I. Silva, A. Ucros
Publikováno v:
Neuropeptides. 18:209-213
SP produces two different muscular responses in the isolated vas deferens of the rat. 1) A myotropic, post-synaptic effect that results from stimulation of one subtype of SP receptor, located on the membrane of the smooth muscle (NK-3 receptor). 2) A
Publikováno v:
General Pharmacology: The Vascular System. 18:425-429
1. 1. The study was undertaken to obtain some information about the development of the autonomic receptors and the AChE activity in the rat vas deferens. 2. 2. The results suggest that the adrenoceptors were fully developed at birth. 3. 3. The M 1 -A
Autor:
H.F. Miranda, W.W. Wolstenholme
Publikováno v:
General Pharmacology: The Vascular System. 15:529-533
Testosterone is able to inhibit the development of tolerance in the smooth muscle of the rat vas deferens. Cycloheximide and actinomycin D also inhibit the tolerance to morphine and ethanol in smooth muscle of rat vas deferens. The toxic effect of cy
Publikováno v:
General Pharmacology: The Vascular System. 18:643-645
1. The effects of hemicholinium (HC-3) on several autonomic agents in the isolated rat vas deferens were investigated. 2. HC-3 reduced slightly the effects of NE and DA. 3. The responses by cholinergic agents on the M1-ACh receptors were not modified
Publikováno v:
General pharmacology. 19(3)
1. 1. The effects of pirenzepine and N -methyl-scopolamine on the responses to ACh in the isolated rat vas deferens were studied. 2. 2. Pirenzepine was inactive at the M 2 -ACh receptor. 3. 3. N -methyl-scopolamine was a competitive antagonist (p A 2
Publikováno v:
General pharmacology. 19(1)
1. The effects of haloperidol on the responses of the isolated rat vasa deferentia to catecholamines and ACh were studied. 2. Haloperidol produced a competitive antagonism to responses elicited by NA and DA in the vas deferens. 3. The M1 and M2 musca
Publikováno v:
Neuropharmacology. 26(10)
Changes in the activity of acetylcholinesterase (AChE) of the isolated vas deferens from normal, castrated, morphine and ethanol-tolerant rats were studied. Three days after the termination of treatment with morphine and on the last day of treatment
Publikováno v:
Neuropeptides. 11(4)
The response of post-synaptic neurokinin receptors to SP were not changed by pirenzepine or N-methyl-scopolamine. Atropine led to a slight increase in the EC 50 of SP for its post-synaptic neurokinin (NK-A) receptor. In the presence of neostigmine no
Autor:
A. Zuazo, J.F. Vergara, F. Rosselot, E. Fernandez, W.W. Wolstenholme, Hugo F. Miranda, E. Perez
Publikováno v:
Pharmacology. 30(3)
In the neuronal electrically stimulated vas deferens of the rat, the responses evoked by morphine, β-endorphin and catecholamines were studied. The tissue was obtained from rats at various times (7–60
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