Zobrazeno 1 - 10
of 101
pro vyhledávání: '"W.T. Stott"'
Autor:
Wallace Yokoyama, Marsha L. Langhorst, Scott A. Young, Hyunsook Kim, Shao-Ching Hung, Maciej Turowski, W.T. Stott, David M. Williams, William H.K. Anderson, Glenn E. Bartley, David R. Albers
Publikováno v:
Journal of Agricultural and Food Chemistry. 60:11149-11156
Cationic hydroxyethyl cellulose (cHEC) was supplemented in a high-fat diet to determine if this new soluble fiber had an effect on hypercholesterolemia and dyslipidemia associated with cardiovascular disease using Golden Syrian hamster as an animal m
Autor:
W.T. Stott, Kathryn M. Kleinert
Publikováno v:
Food and Chemical Toxicology. 46:761-766
Aminoalcohols differ in mammalian toxicity at least in part based upon their ability to alter the metabolism of phospholipids and to cause depletion of the essential nutrient choline in animals. This study examined the incorporation of diisopropanola
Publikováno v:
Regulatory Toxicology and Pharmacology. 43:10-18
To determine potential nitrosation of triethanolamine (TEA) to N-nitrosodiethanolamine (NDELA) at different physiological conditions of the GI tract, in vitro NDELA formation was examined in aqueous reaction mixtures at several pHs (2-10) adjusted wi
Publikováno v:
Regulatory Toxicology and Pharmacology. 39:325-333
The response of animals in toxicity studies reflects a complex interaction of a number of variables, some intrinsic to a particular study design and others resulting from the treatment itself. The influences of strain and diet upon constitutive and b
Publikováno v:
Rapid Communications in Mass Spectrometry. 18:491-498
Direct quantitation of glutathione S-transferase (GST) isoforms [alpha (GST-A) and micro (GST-M)] in human liver cytosol was achieved by liquid chromatography/tandem mass spectrometry (LC/ESI-MS/MS) analysis of signature peptides of GST-A and GST-M a
Publikováno v:
Toxicological Sciences. 71:53-66
Potential factors underlying the tumorigenic activity of ethylbenzene (EB) were examined in F344 rats and B6C3F1 mice inhaling 750 ppm EB vapor 6 h/day, 5 days/week, for one or four weeks. Target tissues (kidneys of rats and livers and lungs of mice)
Publikováno v:
Food and Chemical Toxicology. 39:931-939
In order to better understand the potential toxicity of diethanolamine (DEA) and preparatory to physiologically-based pharmacokinetic model development, the pharmacokinetics of DEA at high and low internal dose through 96-h post-dosing were determine
Publikováno v:
Food and Chemical Toxicology. 38:1043-1051
Triethanolamine (TEA) is an amino alcohol having widespread applications in consumer goods and as an industrial chemical. A number of relatively high-dose dermal toxicity studies have been conducted in rats and mice reflecting the principal route of
Publikováno v:
Environmental Toxicology and Chemistry. 18:2506-2511
The activity of carboxylesterase (CaE), a class of nonspecific serine hydrolases, was evaluated in vitro in tissues and microsomes of rainbow trout and compared to esterase activity in rats, other fish species, and embryo to adult life stages of trou
Publikováno v:
Food and Chemical Toxicology. 35:241-254
A private testing laboratory utilizing the whole-body plethysmograph/head-only exposure apparatus outlined in the respiratory irritation assay ASTM E981-84, along with a novel exposure regimen, has reported neurotoxic effects and mortality in mice ex