Zobrazeno 1 - 10
of 49
pro vyhledávání: '"W.R. Kelce"'
Publikováno v:
Toxicology and Industrial Health. 15:48-64
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca49cec56674edcf122b5fcb8c408db8
https://doi.org/10.1191/074823399678846646
https://doi.org/10.1191/074823399678846646
Publikováno v:
Toxicology and Industrial Health. 15:37-47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ea05e309c5d4fb64631246405458c78
https://doi.org/10.1191/074823399678846655
https://doi.org/10.1191/074823399678846655
Autor:
W.R. Kelce
Publikováno v:
Toxicology and Applied Pharmacology. 125:237-246
Exposure to (EDS) in vivo or in vitro alters adult rat Leydig cell function within 3 hr and these cells subsequently die within 24-48 hr. Previously, we determined that reducing intracellular glutathione levels with buthionine sulfoximine (BSO) prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975268a00876d97be05cc847b9d63b3d
https://doi.org/10.1006/taap.1994.1069
https://doi.org/10.1006/taap.1994.1069
Autor:
Barry R. Zirkin, W.R. Kelce
Publikováno v:
Toxicology and Applied Pharmacology. 120:80-88
We have previously demonstrated that ethane-1,2-dimethane-sulfonate (EDS) kills adult, but not immature, rat Leydig cells in vivo and in vitro. The mechanism responsible for this selective toxicity is not known. Here we report that the cytotoxic effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1fb172c72ac97b2c2270d47889a43db
https://doi.org/10.1006/taap.1993.1089
https://doi.org/10.1006/taap.1993.1089
Publikováno v:
Toxicology and Applied Pharmacology. 111:189-200
Leydig cells from immature rat testes appear to be insensitive to doses of ethane-1,2-dimethanesulfonate (EDS) which eliminate Leydig cells from adult rat testes. We sought to determine whether this differential response to EDS is intrinsic to the Le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4788bcc55ad0496b1ed4e1ce044decf
https://doi.org/10.1016/0041-008x(91)90023-8
https://doi.org/10.1016/0041-008x(91)90023-8
Publikováno v:
Alcohol. 7:75-80
We have previously reported detrimental effects of in utero ethanol exposure on testicular steroidogenic enzyme activity in newborn rats. It is now reported that in utero ethanol exposure during Day 12 of gestation through birth has no apparent morph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19652a4f4ae89f69cf7ca3faaee1b250
https://doi.org/10.1016/0741-8329(90)90063-i
https://doi.org/10.1016/0741-8329(90)90063-i
Publikováno v:
Toxicology and applied pharmacology. 129(1)
In humans and rodents, exposure to hormonally active chemicals during sex differentiation can produce a wide range of abnormal sexual phenotypes including masculinized and defeminized females and feminized and demasculinized males. Although numerous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d2f307d15ac272a9275a983b765585
https://pubmed.ncbi.nlm.nih.gov/7974495
https://pubmed.ncbi.nlm.nih.gov/7974495
Publikováno v:
Journal of steroid biochemistry. 35(1)
The local formation of the testosterone metabolites 5 alpha-dihydrotestosterone and 17 beta-estradiol within the hypothalamic-preoptic area (HPOA) is essential for the normal sexual differentiation of the male central nervous system (CNS) during a pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::013171e979ff4e109a7c7bc328265887
https://pubmed.ncbi.nlm.nih.gov/2308320
https://pubmed.ncbi.nlm.nih.gov/2308320
Publikováno v:
Alcoholism: Clinical and Experimental Research. 13:617-621
We have examined the in utero effects of ethanol exposure on testicular steroidogenesis in newborn male pups. Pregnant Sprague-Dawley rats were fed a liquid ethanol diet (35% ethanol-derived calories), a pair-fed isocaloric liquid diet, or a standard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f5da20b1633ec0a01789580f9c2fbf
https://doi.org/10.1111/j.1530-0277.1989.tb00392.x
https://doi.org/10.1111/j.1530-0277.1989.tb00392.x
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