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Akademický článek

Metyrapone, an inhibitor of cytochrome oxidases, does not affect viability in a neuroblastoma cell model of bilirubin toxicity

Autor: Maria N. Naguib Leerberg, Tomas N. Alme, Thor W.R. Hansen

Publikováno v: Molecular Genetics and Metabolism Reports, Vol 1, Iss C, Pp 197-202 (2014)

Background: Unconjugated hyperbilirubinemia may cause brain damage in infants, and globally remains a source of neonatal morbidity and mortality. A significant inter-individual variability in vulnerability to bilirubin toxicity remains largely unexpl

Externí odkaz: https://doaj.org/article/ebc442da1dd84278b8e884c9dc63138e

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Akademický článek

Methods for Evaluating Tibial Accelerations and Spatiotemporal Gait Parameters during Unsupervised Outdoor Movement.

Autor: Silder, Amy¹ (AUTHOR) silderam@gmail.com, Wong, Ethan J.^1,2 (AUTHOR), Green, Brian^1,2 (AUTHOR), McCloughan, Nicole H.^1,2 (AUTHOR), Hoch, Matthew C.³ (AUTHOR)

Publikováno v: Sensors (14248220). Oct2024, Vol. 24 Issue 20, p6667. 11p.

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Tumour Necrosis Factor-α Regulation of Prostaglandin H Synthase-2 Transcription is not through Nuclear Factor-κB in Amnion-derived AV-3 Cells

Autor: W.R. Hansen, S. Potter, K.W. Marvin, Murray D. Mitchell

Publikováno v: Placenta. 21:789-798

Tumour necrosis factor (TNF)-alpha-stimulated prostaglandin (PG) E(2)biosynthesis by amnion-derived AV3 cells is accompanied by increased prostaglandin H synthase (PGHS)-2 mRNA expression. PGHS-1 mRNA expression is unchanged. PGHS-2 promoter-reporter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef54b4471a5401909926ec764a1a1d6
https://doi.org/10.1053/plac.2000.0576

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NF-IL6 and CRE elements principally account for both basal and interleukin-1beta-induced transcriptional activity of the proximal 528 bp of the PGHS-2 promoter in amnion-derived AV3 cells: evidence for involvement of C/EBPbeta

Autor: Murray D. Mitchell, K.W. Marvin, S. Potter, W.R. Hansen

Publikováno v: Molecular Human Reproduction. 6:771-778

Prostaglandin H synthase (PGHS)-2 promoter fragments (-528 to +9 bp and 5' unidirectional deletions thereof) were cloned upstream of the chloramphenicol acetyl-transferase (CAT) reporter gene. These were transfected into amnion-derived AV3 cells. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b952de68605e0fd8d27d05a722b6d66b
https://doi.org/10.1093/molehr/6.9.771

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Cytokines regulate prostaglandin H synthase-1 transcription in human amnion-derived cells

Autor: W.R. Hansen, Murray D. Mitchell, S. Potter, R.L. Eykholt, K.W. Marvin

Publikováno v: ResearcherID

We have isolated the prostaglandin H synthase-1 (PGHS-1) promoter from the human amnion cell line WISH by long template PCR. The fragment was 1124 base pairs in length and shared a 96% sequence identity with the sequence in GenBank. The putative tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4308ed57906cbc84184572c64eb9bdeb
https://doi.org/10.1054/plef.1999.0108

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Amnion-derived cells express intercellular adhesion molecule-1: regulation by cytokines

Autor: K.W. Marvin, W.R. Hansen, Mitchell, HC Miller, R.L. Eykholt

Publikováno v: ResearcherID

We have examined the expression of the intercellular adhesion molecule-1 (ICAM-1) mRNA in primary and established amnion-derived cell cultures and regulation of this expression by tumour necrosis factor-alpha (TNF-alpha) and interleukin (IL)-1beta. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083a754981f1c3df152e41c27c6a9e53
https://doi.org/10.1677/jme.0.0220193

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Interleukin-4 differentially regulates prostaglandin production in amnion-derived WISH cells stimulated with pro-inflammatory cytokines and epidermal growth factor

Autor: Timothy A. Sato, J.S. Gilmour, Nuala A. Helsby, Murray D. Mitchell, Jeffrey A. Keelan, W.R. Hansen, D.K. Gupta

Publikováno v: ResearcherID

Cytokines and growth factors have been proposed to act as in vivo modulators of amnion prostaglandin production at parturition. To characterize the effects of the 'anti-inflammatory' cytokine interleukin (IL)-4 on amnion prostaglandin production, amn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b8f298f012b8d5c113915109dad115
https://doi.org/10.1054/plef.1999.0033

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Effects of interleukin-4 on the expression and activity of prostaglandin endoperoxide H synthase-2 in amnion-derived WISH cells

Autor: J.S. Gilmour, Ta Sato, Jeffrey A. Keelan, Mitchell, W.R. Hansen, HC Miller

Publikováno v: ResearcherID

Increased prostaglandin biosynthesis during intrauterine infection may be a possible mechanism by which preterm labour is initiated. Inflammatory cytokines and growth factors are known to stimulate prostaglandin production through an increase in pros

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01cb017ab86f200f3c67f16b5856795e
https://doi.org/10.1677/jme.0.0210317

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Characterization of the amnion-derived AV3 cell line for use as a model for investigation of prostaglandin-cytokine interactions in human amnion

Autor: S. Potter, W.R. Hansen, Murray D. Mitchell, Jeffrey A. Keelan

Publikováno v: ResearcherID

Increased production of prostaglandins and cytokines by amnion, particularly prostaglandin (PG) E-2, interleukin (IL)-6 and IL-8, is thought to be an important event in infection-associated preterm labour. We characterized the amnion-derived AV3 cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa72f4e13d98ed3858f4466124b9287c
https://pubmed.ncbi.nlm.nih.gov/10718111

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