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pro vyhledávání: '"W.R Mathews"'
Akademický článek
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Autor:
W.R. Mathews, Matthew D Cascino, Alyssa Morimoto, Ann Herman, Qingling Li, Peter Liu, Tamiko R. Katsumoto, Veronica G. Anania, L.L. Dragone, Wendy Sandoval
Publikováno v:
Free Communications 1—Biomarker discovery.
Background and aims Lupus nephritis (LN) is a clinical manifestation of systemic lupus erythematosus (SLE) associated with significant morbidity and mortality. Although proteinuria is highly correlated with disease progression in LN, the composition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e988d3475fa485f519445608a1b6e3a5
https://doi.org/10.1136/lupus-2017-000215.38
https://doi.org/10.1136/lupus-2017-000215.38
Autor:
W.R. Mathews, Olga V. Nemirovskiy, M.G. Jennings, Micky D. Tortorella, Anne-Marie Malfait, D.R. Dufield
Publikováno v:
Analytical Biochemistry. 406:113-123
The degradation of articular cartilage by aggrecanases (ADAMTS-4 and ADAMTS-5) plays a significant role in the pathology of osteoarthritis (OA). To monitor aggrecanase activity in OA, we have developed a sensitive, accurate, and versatile assay for d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3cdd47401a6d0c077dab510949e099
https://doi.org/10.1016/j.ab.2010.06.044
https://doi.org/10.1016/j.ab.2010.06.044
Autor:
Olga V. Nemirovskiy, W.R. Mathews, M.-P. Hellio Le Graverand, T. Sunyer, Poonam Aggarwal, M. Abrams
Publikováno v:
Osteoarthritis and Cartilage. 16(12):1494-1500
Summary Objective Progression of joint damage in osteoarthritis (OA) is likely to result from an imbalance between cartilage degradation and synthesis processes. Markers reflecting these two components appear to be promising in predicting the rate of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb57b04079d88ba8cf5b6aaeaacda3a
Publikováno v:
Analytical Biochemistry. 361:93-101
Destruction of cartilage by matrix metalloproteinases (MMPs) plays a significant role in the pathology of osteoarthritis (OA). A translatable biomarker of MMP activity would enable development of MMP inhibitors for the treatment of OA and potentially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589b5e06b7536491158a2ba6b717b618
https://doi.org/10.1016/j.ab.2006.10.034
https://doi.org/10.1016/j.ab.2006.10.034
Publikováno v:
Shock. 4:282-288
The potential role of nitric oxide (NO) was investigated in the pathophysiology of liver injury after priming with 20 min hepatic ischemia-reperfusion and administration of .5 mg/kg Salmonella enteritidis endotoxin. Liver injury during the early repe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2118c2f0608a240355c9d1502ef548
https://doi.org/10.1097/00024382-199510000-00009
https://doi.org/10.1097/00024382-199510000-00009
Autor:
Julie Rae, Wendy Sandoval, Peter Liu, L.L. Dragone, Tamiko R. Katsumoto, Caroline Looney, Matthew D Cascino, Alyssa Morimoto, Ann Herman, Veronica G. Anania, M. Neighbors, W.R. Mathews
Publikováno v:
Annals of the Rheumatic Diseases. 75:950.1-950
Background Lupus nephritis (LN) is a severe clinical manifestation of systemic lupus erythematosus (SLE) associated with significant morbidity and mortality. Assessment of severity and activity of renal involvement in SLE requires a kidney biopsy, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::441c77ff58b777c9487b3740688ca210
https://doi.org/10.1136/annrheumdis-2016-eular.4468
https://doi.org/10.1136/annrheumdis-2016-eular.4468
Publikováno v:
Fibrinolysis. 8:31-41
The asparagine-linked oligosaccharides on a recombinant tissue-type plasminogen activator analog, lacking the epidermal growth factor-like and kringle 1 domains (FK 2 P), synthesized by Chinese hamster ovary cells, have been characterized. In vivo [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a928ac0fe9946746276cf5e337978ecc
https://doi.org/10.1016/0268-9499(94)90029-9
https://doi.org/10.1016/0268-9499(94)90029-9
Publikováno v:
Prostaglandins. 45:347-361
The metabolism of leukotriene B4 (5(S),12(R)-dihydroxy-6-cis-8,10-trans-14-cis-eicosatetraenoic acid) by isolated guinea pig eosinophils was investigated. Incubation of guinea pig eosinophils with [3H]-leukotriene B4 resulted in the rapid conversion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5455c8ee36d401f7771a4f8f95d40933
https://doi.org/10.1016/0090-6980(93)90112-k
https://doi.org/10.1016/0090-6980(93)90112-k
Publikováno v:
Biochemistry. 31:6951-6961
Prorenin was isolated by immunoprecipitation from the culture medium of Chinese hamster ovary cells transfected with a human prorenin cDNA. The N-linked oligosaccharide structures on the in vivo [3H]mannose-labeled, purified protein were characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ced3adfed48a17c5041c58f4cbf99c53
https://doi.org/10.1021/bi00145a013
https://doi.org/10.1021/bi00145a013