Zobrazeno 1 - 10 of 1 920 pro vyhledávání: '"W.K. Chung"'
1
Akademický článek
Alpha galactosidase A activity in Parkinson's disease
Autor: R.N. Alcalay, P. Wolf, O.A. Levy, U.J. Kang, C. Waters, S. Fahn, B. Ford, S.H. Kuo, N. Vanegas, H. Shah, C. Liong, S. Narayan, M.W. Pauciulo, W.C. Nichols, Z. Gan-Or, G.A. Rouleau, W.K. Chung, P. Oliva, J. Keutzer, K. Marder, X.K. Zhang
Publikováno v: Neurobiology of Disease, Vol 112, Iss , Pp 85-90 (2018)
Glucocerebrosidase (GCase, deficient in Gaucher disease) enzymatic activity measured in dried blood spots of Parkinson's Disease (PD) cases is within healthy range but reduced compared to controls. It is not known whether activities of additional lys
Externí odkaz: https://doaj.org/article/2d3c35c920664143a7a6fbfadca77476
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2
Akademický článek
The driver role of JAK‐STAT signalling in cancer stemness capabilities leading to new therapeutic strategies for therapy‐ and castration‐resistant prostate cancer
Autor: U‐Ging Lo, Yu‐An Chen, Junjie Cen, Su Deng, Junghang Luo, Haiyen Zhau, Lin Ho, Chih‐Ho Lai, Ping Mu, Leland W.K. Chung, Jer‐Tsong Hsieh
Publikováno v: Clinical and Translational Medicine, Vol 12, Iss 8, Pp n/a-n/a (2022)
Abstract Background Lineage plasticity in prostate cancer (PCa) has emerged as an important mechanism leading to the onset of therapy‐ and castration‐resistant PCa (t‐CRPC), which is closely associated with cancer stem cell (CSC) activity. This
Externí odkaz: https://doaj.org/article/1aad9987d3304f14983bd01cc6d7fd17
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5
Figures S1-S5 from R1 Regulates Prostate Tumor Growth and Progression By Transcriptional Suppression of the E3 Ligase HUWE1 to Stabilize c-Myc
Autor: Jean C. Shih, Boyang Jason Wu, Leland W.K. Chung, Haiyen E. Zhau, Chi-Hung Lin, Gina Chia-Yi Chu, Jen-Ming Huang, Ni Zeng, Chunyan Liu, Xiangyan Li, Qinlong Li, Jingjing Li, Tzu-Ping Lin
Figure S1: R1 does not affect contact inhibition during prostate cancer cell proliferation; Figure S2: R1 does not affect cell apoptosis in prostate cancer cells under both steady state and dynamic conditions; Figure S3: R1 promotes prostate cancer c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50375be7b4a8667cadc65f4e54a1c6b
https://doi.org/10.1158/1541-7786.22511707
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6
Data from Novel Mitochondria-Based Targeting Restores Responsiveness in Therapeutically Resistant Human Lung Cancer Cells
Autor: Leland W.K. Chung, Qinghua Zhou, Haiyen E. Zhau, Ruoxiang Wang, Michael S. Lewis, Yan Ou, Lijuan Yin, Yi Zhang, Liyuan Yin
Cisplatin and tyrosine kinase inhibitors (TKI) are recommended to treat non–small cell lung cancer (NSCLC). However, ubiquitously acquired drug resistance in patients with NSCLC diminishes their therapeutic efficacy. Strategies for overcoming cispl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e24a277220bb1dc4e4db0087d388bb6
https://doi.org/10.1158/1535-7163.c.6543409.v1
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7
Data from A Novel Salicylanilide Derivative Induces Autophagy Cell Death in Castration-Resistant Prostate Cancer via ER Stress-Activated PERK Signaling Pathway
Autor: Shian-Ying Sung, Leland W.K. Chung, Chih-Ying Chiang, Teigi Saka, Kuan-Chou Chen, Hsu-Shan Huang, Chia-Ling Hsieh
Metastatic castration-resistant prostate cancer (CRPC) is currently incurable. Cancer growth and progression is intimately affected by its interaction with host microenvironment. Cotargeting of the stroma and prostate cancer is therefore an emerging
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::147a939d417bbbd59a654caaf29ce648
https://doi.org/10.1158/1535-7163.c.6538525.v1
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10
Akademický článek
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