Zobrazeno 1 - 10
of 227
pro vyhledávání: '"W.J. Gullick"'
Publikováno v:
European Journal of Cancer. 33:1846-1850
c-erbB-3, A recently identified member of the type I tyrosine kinase receptor family, has been shown to be overexpressed in invasive ductal carcinoma of breast. In this study, expression of the c-erbB-3 protein was examined in 57 cases of pure ductal
Publikováno v:
International journal of oncology. 6(1)
The c-erbB3 protein is a member of the type 1 tyrosine kinase growth factor receptor family. We report on the production and characterisation of a monoclonal antibody, RTJ2, raised against a synthetic peptide from the cytoplasmic domain of the molecu
Publikováno v:
Journal of Clinical Pathology. 46:149-153
AIMS: To investigate the pattern of epidermal growth factor receptor expression and its prognostic value in the three main types of cervical carcinoma. METHODS: 62 cases of stage IB/IIA cervical carcinoma, all with a minimum of five years of follow u
Autor:
H. C. Hurst, Sally A. Prigent, P. Smith, Christine M. Hughes, W.J. Gullick, Edwin A. Dublin, N. R. Lemoine, D. P. Hollywood, Diana M. Barnes
Publikováno v:
British Journal of Cancer
Abnormalities of the EGF receptor and/or the related ERBB2 receptor occur in a significant proportion of cases of human breast cancer and are important influences in the behaviour of this tumour type. In this report we demonstrate by nucleic acid ana
Publikováno v:
Human Pathology. 21:1164-1167
The presence of the c- erb B-2 protein, demonstrated immunohistochemically with antibody 21N, has been studied in 72 cases of pure mammary ductal carcinoma in situ. Sixty-one percent of cases showed positive staining. The protein was always present i
Autor:
W.J. Gullick
Publikováno v:
Progress in Growth Factor Research. 2:1-13
The growth of normal breast epithelial cells is regulated by a complex interacting system of polypeptide factors and by steroid hormones. The cells respond to these factors through receptors which generate mitogenic and other intracellular signals. T
Autor:
W.J. Gullick, A.H. Handyside
Publikováno v:
European Journal of Cancer. 30:2030-2032
Autor:
W.J. Gullick
Publikováno v:
Human & Experimental Toxicology. 10:398-400
Publikováno v:
International Journal of Oncology.
The expression of amphiregulin (AR) and cripto (CR-1), two recently identified growth factor peptides, has been evaluated in 196 mammary carcinomas, 13 biopsies of normal breast and 17 benign breast lesions using immunohistochemical methods. Strong i
Publikováno v:
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. 5(4)
Over-expression of epidermal growth factor receptor (EGFR) andc-erbB-2, in uterine cervical carcinomas, is associated with a worsened prognosis. A third member of this proto-oncogene family,c-erbB-3, has now been identified and its over-expression ha