Zobrazeno 1 - 10
of 77
pro vyhledávání: '"W.I.P. MAINWARING"'
Autor:
W.I.P. Mainwaring
My introduction to androgens was neither auspicious nor impressive. I was sitting my viva voce examination for a degree in physiology and had haltingly intimated to my examiner (name decorously withheld) that I intended to pursue a career in re sea
Autor:
W.I.P. Mainwaring, Valerie A. Randall
Publikováno v:
Journal of Steroid Biochemistry. 21:209-216
In the absence of photoexcitation and under conditions of low ionic strength, the native form of the androgen receptor in rat prostate sediments as a large, 9.2S complex with tritiated androgens, including [3H]methyltrienolone. On photoexcitation, th
Autor:
W.I.P. Mainwaring, Malcolm G. Parker
Publikováno v:
Journal of Steroid Biochemistry. 9:455-460
The effect of androgens on RNA production in rat ventral prostate has been studied by analysing the base sequence complexity of cytoplasmic poly(A)-containing RNA from normal and castrated rats. The kinetics of hybridization of RNA from normal animal
Autor:
N.S. Derry, W.I.P. Mainwaring
Publikováno v:
Journal of Steroid Biochemistry. 19:101-108
Androgens stringently regulate the concentrations of the polyamines, spermine and spermidine, in rat ventral prostate. The intracellular distribution of the polyamines is also dependent on the androgenic milieu; a small proportion of polyamines is as
Publikováno v:
Molecular and Cellular Endocrinology. 1:113-128
Somewhat surprisingly in view of its chemical constitution, SCH 13521 antagonises the biological activity of testosterone in vivo in a manner reminiscent of the steroid-related anti-androgen, cyproterone acetate. Accordingly, SCH 13521 severely curta
Autor:
W.I.P. Mainwaring, R. Iirving
Publikováno v:
Journal of Steroid Biochemistry. 5:711-716
1. 1. The propensity of steroid-receptor complexes for native DNA immobilized on cellulose, together with their relatively acidic isoelectric point, may be exploited as means of partial purification. 2. 2. A critical appraisal of these procedures is
Autor:
W.I.P. Mainwaring
Publikováno v:
Gerontology. 13:177-189
Autor:
T. Hofmann, W.I.P. Mainwaring
Publikováno v:
Archives of Biochemistry and Biophysics. 125:975-980
The presence of an N -acetyl serine residue at the N-terminal side of the peptide chain of the apoferritin subunits has been confirmed. Quantitative determination of the bound acetyl groups gives a value of 19.6 ± 1 moles per mole apoferritin (mol.
Autor:
W.I.P. Mainwaring
Publikováno v:
Gerontology. 14:133-141
Autor:
W.I.P. Mainwaring
Publikováno v:
Biochemical and Biophysical Research Communications. 40:192-198
Measurements of 5α-reductase and androgen receptor activities were performed on subnuclear fractions of rat prostate nuclei to establish whether these activities are conducted by a single nuclear-associated protein. Differences in intranuclear local