Výsledky vyhledávání - "W.H. Doesburg"

The effect of ethyldeshydroxy-sparsomycin and cisplatin on the intracellular glutathione level and glutathione S-transferase activity

Autor: H. P. Hofs, W.J. de Grip, W.H. Doesburg, D.J.T. Wagener, H. van Rennes, Harry C. J. Ottenheijm, V. de Valk-Bakker

Publikováno v: Anti-Cancer Drugs, 8, pp. 349-357
Anti-Cancer Drugs, 8, 349-357
Anti-Cancer Drugs, 8, 4, pp. 349-357

Ethyldeshydroxy-sparsomycin (EdSm) is a ribosomal protein synthesis inhibitor which synergistically enhances the antitumor activity of cisplatin against L1210 leukemia in vivo. Because cellular glutathione (GSH) and glutathione S-transferases (GST) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1849fa940128afdbdccccade20331255
https://doi.org/10.1097/00001813-199704000-00007

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Original Articles: Bladder Cancer: A Randomized Study of Intravesical Mitomycin C, Bacillus Calmette-Guerin Tice and Bacillus Calmette-Guerin RIVM Treatment in pTa-pT1 Papillary Carcinoma and Carcinoma in Situ of the Bladder

Autor: J. Alfred Witjes, P. D. J. Vegt, W.P.J. Witjes, W.H. Doesburg, E. David Crawford, A.P.M. van der Meijden, Frans M.J. Debruyne

Publikováno v: Journal of Urology. 153:929-933

Results of a randomized prospective study are reported in which mitomycin C, Tice bacillus Calmette-Guerin (BCG) and RIVM-BCG were compared in 437 patients with primary or recurrent pTa and pT1 bladder tumors, including carcinoma in situ. The followu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e12e32370b786663618687ca5710f02d
https://doi.org/10.1016/s0022-5347(01)67606-7

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A randomised prospective study comparing intravesical instillations of mitomycin-C, BCG-Tice, and BCG-RIVM in pTa-pT1 tumours and primary carcinoma in situ of the urinary bladder

Autor: A.P.M.v.d. Meijden, H.E. Schaafsma, J.A. Witjes, W.P.J. Witjes, W.H. Doesburg, Frans M.J. Debruyne

Publikováno v: European Journal of Cancer. 29:1672-1676

We compared intravesical instillations with mitomycin-C (MMC), Bacillus Calmette-Guerin (BCG) Tice, and BCG-RIVM in patients with pTa-pT1 papillary carcinoma and primary carcinoma in situ (CIS) of the bladder. Nine instillations with MMC were given o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d47fcae2da4d563ab597775b2e41258f
https://doi.org/10.1016/0959-8049(93)90102-l

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Use of Maintenance Intravesical Bacillus Calmette-Guérin (BCG), with or without Intradermal BCG, in Patients with Recurrent Superficial Bladder Cancer

Autor: A.P.M. van der Meijden, Frans M.J. Debruyne, J.A. Witjes, M.P.H. Fransen, W.H. Doesburg

Publikováno v: Urologia Internationalis. 51:67-72

To study maintenance Bacillus Calmette-Guerin (BCG) therapy we treated 49 patients with recurrent superficial bladder cancer pTa and/or carcinoma in situ, failing previous intravesical chemotherapy. They received 20 intravesical instillations in 1 ye

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4ea13d6a8f3533ec3c90c0c5fe82c37
https://doi.org/10.1159/000282516

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Influence of Fibrin Clot Inhibitors on the Efficacy of Intravesical Bacillus Calmette-Guérin in the Treatment of Superficial Bladder Cancer

Autor: W.H. Doesburg, Frans M.J. Debruyne, J.A. Witjes, Adrian P.M. van der Meijden

Publikováno v: European Urology. 23:366-370

After transurethral resection (TUR) of superficial bladder tumors, intravesical instillations with BCG are successfully used to lower the recurrence rate. The mechanism of the antitumor activity of BCG is not completely understood. After TUR, a fibri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::586d0862d763a8ff4da0a879e5691252
https://doi.org/10.1159/000474631

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Pre-induction intracervical application of a highly viscous prostaglandin E2 gel in pregnant women with an unripe uterine cervix: a double-blind placebo-controlled trial

Autor: J.B.C. van Veen, A.L. Troostwijk, W.H. Doesburg

Publikováno v: European Journal of Obstetrics & Gynecology and Reproductive Biology. 43:105-111

Intracervical application of prostaglandin E 2 (PGE 2 ) gel has shown to be an effective method for pre-induction cervical ripening in pregnant women with an unripe uterine cervix. Side effects are minimal, provided that the instillation is carefully

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf4c622778247908e85c410406de671
https://doi.org/10.1016/0028-2243(92)90066-8

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Comparison of the Diagnostic Value of Pump and Gravity Cavernosometry in the Evaluation of the Cavernous Veno-Occlusive Mechanism

Autor: Eric J.H. Meuleman, W.H. Doesburg, Frans M.J. Debruyne, Hessel Wijkstra

Publikováno v: Journal of Urology. 146:1266-1270

We performed cavernosometry in 96 patients with erectile dysfunction. Two different techniques were compared: pump cavernosometry using a roller pump as the inflow source and gravity cavernosometry using an infusion set as the inflow source. We concl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50643d9e35a866f3888b087e0c859c8e
https://doi.org/10.1016/s0022-5347(17)38065-5

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Phase I/II study of recombinant interferon α and γ in advanced progressive renal-cell carcinoma

Autor: Ad G. M. Reintjes, Simon Strijk, Mart P. H. Franssen, Frans M.J. Debruyne, Otto Damsma, Arno D. H. Geboers, Pieter H.M. De Mulder, W.H. Doesburg

Publikováno v: Cancer Immunology, Immunotherapy. 31:321-324

In vitro studies have documented the synergistic antiviral and antiproliferative activity of recombinant interferon alpha (rIFN alpha) and rIFN gamma. Furthermore, rIFN gamma is a strong immunomodulator with optimal effects at a relative low dose (0.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070e9541327d1ca57a939c948cfc4e2c
https://doi.org/10.1007/bf01740941

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Human choriogonadotropin (hCG): comparisons between determinations of intact hCG, free hCG beta-subunit, and 'total' hCG + beta in serum during the first half of high-risk pregnancy

Autor: Chris M. G. Thomas, M. F. G. Segers, R. Rolland, W.H. Doesburg, F. J. L. Reijnders

Publikováno v: Clinical Chemistry. 36:651-655

We have studied the concentrations of intact human choriogonadotropin (hCG) and the free hCG beta-subunit in blood samples from singleton pregnancies at risk for habitual or threatened abortion. The samples were obtained weekly between the 6th and 12

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a36fcc44be05bc40507dab9bafca7241
https://doi.org/10.1093/clinchem/36.4.651

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Improvement of cervical mucus viscoelasticity and sperm penetration with sodium bicarbonate douching

Autor: E. Everhardt, H. Jansen, W.H. Doesburg, J.M.J. Dony, W.A.J.G. Lemmens

Publikováno v: Human Reproduction. 5:133-137

The aim of the study was to evaluate the influence of vaginal douching with sodium bicarbonate (NaHCO3) upon cervical mucus viscoelasticity and sperm penetration in vitro and in vivo. Twenty-five couples with primary infertility for greater than 12 m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108493cff1333ce58222a3429ed8445e
https://doi.org/10.1093/oxfordjournals.humrep.a137056

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