Zobrazeno 1 - 10
of 118
pro vyhledávání: '"W.F. Bayne"'
Publikováno v:
Journal of Pharmaceutical Sciences. 82:1145-1150
A theoretical investigation has been conducted to understand the deconvolution method used for evaluating the in vivo release rate of an oral controlled-release product from the plasma drug concentration versus time profile. The theory is based on we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40cf9c30498e8d1ad330b544ced1b32e
https://doi.org/10.1002/jps.2600821116
https://doi.org/10.1002/jps.2600821116
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 566:127-134
A high-performance liquid chromatographic (HPLC) method with ultraviolet detection for the determination of a novel 4-aza-steroidal inhibitor of 5α-reductase in human plasma has been developed. The assay is based on a single solid-phase extraction a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0e33fcd15c0f0b2dfc4c39377b657db
https://doi.org/10.1016/0378-4347(91)80117-u
https://doi.org/10.1016/0378-4347(91)80117-u
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 9:511-516
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0094e64118d32d55e5c0a812e74d6b60
https://doi.org/10.1016/0731-7085(91)80255-8
https://doi.org/10.1016/0731-7085(91)80255-8
Publikováno v:
Pharmaceutical Research. :33-39
Imipenem (thienamycin formamidine) is an antibiotic active against a broad spectrum of bacteria. Its primary metabolite arises from cleavage of the lactam ring. The metabolite can be formed in-vitro by acid-catalyzed or enzymatic hydrolysis. In anima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb8f2f2027a5ea933ce3feda2dcd7a99
https://doi.org/10.1023/a:1015818004113
https://doi.org/10.1023/a:1015818004113
Publikováno v:
Analytical Chemistry. 62:1308-1315
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9831a8f9491b8790678642252d3caba4
https://doi.org/10.1021/ac00212a020
https://doi.org/10.1021/ac00212a020
Publikováno v:
Drug Investigation. 2:18-28
Lovastatin (mevinolin) [LV], simvastatin (epistatin) [SV] and pravastatin (eptastatin) [PVA] are indicated in the treatment of hypercholesterolaemia and are potent inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase. Beagle dogs w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee404b935b4dea4e998b46e66eb11468
https://doi.org/10.1007/bf03258190
https://doi.org/10.1007/bf03258190
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 534:139-149
A sensitive (5 ng/ml) method for the determination of 4-amino-1-hydroxybutane-1,1-bisphosphonic acid in human urine is described. The procedure includes (1) the isolation of the drug from urine by co-precipitation of its calcium salt with endogenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295ed6a61263d3f6973c4a3f0ef6fde0
https://doi.org/10.1016/s0378-4347(00)82156-8
https://doi.org/10.1016/s0378-4347(00)82156-8
Autor:
J.D. Rogers, Donald G. Musson, Bogdan K. Matuszewski, W.F Bayne, James Dru, Eric Woolf, John Y.-K. Hsieh, A.M Cairns, Kimberly L. Birk, J.L. Demetriades
Publikováno v:
Journal of chromatography. B, Biomedical sciences and applications. 719(1-2)
A novel, highly sensitive method for the determination of pilocarpic acid (PA) in human plasma is described. In addition, the method provides for the conversion of the lactone, pilocarpine (P), to PA so that a total drug presence can be determined. U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7569cc8fd891c3f5efed6c2c7bcc996
https://pubmed.ncbi.nlm.nih.gov/9869369
https://pubmed.ncbi.nlm.nih.gov/9869369
Publikováno v:
Biological mass spectrometry. 22(1)
A general method for the assay of the 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors lovastatin, pravastatin, and simvastatin in plasma has been developed and validated. The analytes are isolated from plasma by a solid-phase ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc55cb2226bb318a6bb5cf4b6d797ae
https://pubmed.ncbi.nlm.nih.gov/8431499
https://pubmed.ncbi.nlm.nih.gov/8431499
Publikováno v:
Journal of chromatography. 534
Two assay procedures are described for the analysis of levodopa, carbidopa and 3-O-methyldopa in plasma and levodopa, carbidopa and dopamine in urine. The methods are suitable for quantifying the analytes following therapeutic administration of levod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e71b8c55d638aee7f6e553be7b17ae
https://pubmed.ncbi.nlm.nih.gov/2094725
https://pubmed.ncbi.nlm.nih.gov/2094725