Zobrazeno 1 - 10
of 1 123
pro vyhledávání: '"W. van der Kamp"'
Autor:
Helen M. Deeks, Kirill Zinovjev, Jonathan Barnoud, Adrian J. Mulholland, Marc W. van der Kamp, David R. Glowacki
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract We describe a two-step approach for combining interactive molecular dynamics in virtual reality (iMD-VR) with free energy (FE) calculation to explore the dynamics of biological processes at the molecular level. We refer to this combined appr
Externí odkaz:
https://doaj.org/article/60f7f91f6cae4fdcb4ced23c5de8bc8f
Autor:
Stafleu, M.D.
Publikováno v:
Philosophia Reformata, 1987 Jan 01. 52(1), 82-84.
Externí odkaz:
https://www.jstor.org/stable/24707905
Autor:
Rory M. Crean, Bruce J. MacLachlan, Florian Madura, Thomas Whalley, Pierre J. Rizkallah, Christopher J. Holland, Catriona McMurran, Stephen Harper, Andrew Godkin, Andrew K. Sewell, Christopher R. Pudney, Marc W. van der Kamp, David K. Cole
Publikováno v:
Molecular Therapy: Oncolytics, Vol 18, Iss , Pp 443-456 (2020)
Immuno-oncology approaches that utilize T cell receptors (TCRs) are becoming highly attractive because of their potential to target virtually all cellular proteins, including cancer-specific epitopes, via the recognition of peptide-human leukocyte an
Externí odkaz:
https://doaj.org/article/468343d29a914222a4306cde545a8b9d
Autor:
Ieva Drulyte, Jana Obajdin, Chi H. Trinh, Arnout P. Kalverda, Marc W. van der Kamp, Glyn R. Hemsworth, Alan Berry
Publikováno v:
IUCrJ, Vol 6, Iss 6, Pp 1120-1133 (2019)
Indanomycin is biosynthesized by a hybrid nonribosomal peptide synthase/polyketide synthase (NRPS/PKS) followed by a number of `tailoring' steps to form the two ring systems that are present in the mature product. It had previously been hypothesized
Externí odkaz:
https://doaj.org/article/1d7033a8f6d9495181411cd7ea98934b
Autor:
Kyle Rice, Kissa Batul, Jacqueline Whiteside, Jayne Kelso, Monica Papinski, Edward Schmidt, Alena Pratasouskaya, Dacheng Wang, Rebecca Sullivan, Christopher Bartlett, Joel T. Weadge, Marc W. Van der Kamp, Gabriel Moreno-Hagelsieb, Michael D. Suits, Geoff P. Horsman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Phosphonate modifications can be present on microbial cell surfaces. Here the authors perform bioinformatics analyses and observe a widespread occurrence of nucleotidyltransferase-encoding genes in bacterial phosphonate biosynthesis and functionally
Externí odkaz:
https://doaj.org/article/851a3355841b4f708a43a502942c9977
Autor:
Christopher Fröhlich, João A. Gama, Klaus Harms, Viivi H. A. Hirvonen, Bjarte A. Lund, Marc W. van der Kamp, Pål J. Johnsen, Ørjan Samuelsen, Hanna-Kirsti S. Leiros
Publikováno v:
mSphere, Vol 6, Iss 2 (2021)
Very low antibiotic concentrations have been shown to drive the evolution of antimicrobial resistance. While substantial progress has been made to understand the driving role of low concentrations during resistance development for different antimicro
Externí odkaz:
https://doaj.org/article/276c05fc829f41be9f75792752a53d86
Publikováno v:
PeerJ Physical Chemistry, Vol 2, p e8 (2020)
To assess the accuracy of different quantum mechanical methods for biochemical modeling, the reaction energies of 20 small model reactions (chosen to represent chemical steps catalyzed by commonly studied enzymes) were calculated. The methods tested
Externí odkaz:
https://doaj.org/article/e5e9a64ab99a4c4c8f84245bf73d461c
Autor:
Friedrich Schierbaum
Publikováno v:
Starch - Stärke. 56:552-552
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38c1b4cd4f9c3f27d9fa43d79df0e06c
https://doi.org/10.1002/star.200490064
https://doi.org/10.1002/star.200490064
Autor:
Marc W. van der Kamp, Erica J. Prentice, Kirsty L. Kraakman, Michael Connolly, Adrian J. Mulholland, Vickery L. Arcus
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Heat capacity changes affect the temperature dependence of enzyme catalysis, with implications for thermoadaptation, however their physical basis is unknown. Here the authors show that heat capacity changes are calculable by simulation, revealing dis
Externí odkaz:
https://doaj.org/article/d40e1dcd15e6492cbf102e64d92191d2
Autor:
Sarah A. Hindson, Rachael C. Andrews, Michael J. Danson, Marc W. van der Kamp, Amy E. Manley, Oliver B. Sutcliffe, Tom S. F. Haines, Tom P. Freeman, Jennifer Scott, Stephen M. Husbands, Ian S. Blagbrough, J. L. Ross Anderson, David R. Carbery, Christopher R. Pudney
Publikováno v:
The FEBS Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69651668a6e2c61d655cceedf45ebe22
https://doi.org/10.1111/febs.16741
https://doi.org/10.1111/febs.16741