Adjuvant dendritic cell therapy in stage IIIB/C melanoma: the MIND-DC randomized phase III trial

Autor: Kalijn F. Bol, Gerty Schreibelt, Martine Bloemendal, Wouter W. van Willigen, Simone Hins-de Bree, Anna L. de Goede, Annemiek J. de Boer, Kevin J. H. Bos, Tjitske Duiveman-de Boer, Michel A. M. Olde Nordkamp, Tom G. M. van Oorschot, Carlijn J. Popelier, Jeanne M. Pots, Nicole M. Scharenborg, Mandy W. M. M. van de Rakt, Valeska de Ruiter, Wilmy S. van Meeteren, Michelle M. van Rossum, Sandra J. Croockewit, Bouke J. Koeneman, Jeroen H. A. Creemers, Inge M. N. Wortel, Caroline Angerer, Mareke Brüning, Katja Petry, Andrzej Dzionek, Astrid A. van der Veldt, Dirk J. van Grünhagen, Johanna E. M. Werner, Johannes J. Bonenkamp, John B. A. G. Haanen, Marye J. Boers-Sonderen, Rutger H. T. Koornstra, Martijn F. Boomsma, Erik H. J. Aarntzen, Martin Gotthardt, James Nagarajah, Theo J. M. de Witte, Carl G. Figdor, Johannes H. W. de Wilt, Johannes Textor, Jan Willem B. de Groot, Winald R. Gerritsen, I. Jolanda M. de Vries

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)

Abstract Autologous natural dendritic cells (nDCs) treatment can induce tumor-specific immune responses and clinical responses in cancer patients. In this phase III clinical trial (NCT02993315), 148 patients with resected stage IIIB/C melanoma were r

Externí odkaz: https://doaj.org/article/245269452ff04a81b46a9a6846fb6516

Response and survival of metastatic melanoma patients treated with immune checkpoint inhibition for recurrent disease on adjuvant dendritic cell vaccination

Autor: Wouter W. van Willigen, Martine Bloemendal, Marye J. Boers-Sonderen, Jan Willem B. de Groot, Rutger H.T. Koornstra, Astrid A.M. van der Veldt, John B. A. G. Haanen, Steve Boudewijns, Gerty Schreibelt, Winald R. Gerritsen, I. Jolanda M. de Vries, Kalijn F. Bol

Publikováno v: OncoImmunology, Vol 9, Iss 1 (2020)

Vaccination with autologous dendritic cells (DC) loaded ex vivo with melanoma-associated antigens is currently being tested as an adjuvant treatment modality for resected locoregional metastatic (stage III) melanoma. Based on its mechanism of action,

Externí odkaz: https://doaj.org/article/883495aae3294bf5ba2d0568adb468a3

Response and survival of metastatic melanoma patients treated with immune checkpoint inhibition for recurrent disease on adjuvant dendritic cell vaccination

Autor: Marye J Boers-Sonderen, Kalijn F. Bol, Rutger H. T. Koornstra, Wouter W. van Willigen, John B. A. G. Haanen, Astrid A M van der Veldt, Gerty Schreibelt, Jan Willem B. de Groot, Martine Bloemendal, I. Jolanda M. de Vries, Winald R. Gerritsen, Steve Boudewijns

Publikováno v: OncoImmunology, 9(1):1738814. Landes Bioscience
Oncoimmunology, 9, 1
Oncoimmunology
article-version (VoR) Version of Record
OncoImmunology, Vol 9, Iss 1 (2020)
Oncoimmunology, 9

Vaccination with autologous dendritic cells (DC) loaded ex vivo with melanoma-associated antigens is currently being tested as an adjuvant treatment modality for resected locoregional metastatic (stage III) melanoma. Based on its mechanism of action,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20f2455902765725db439747d337bd2
https://doi.org/10.1080/2162402x.2020.1738814

18F-FDG PET/CT of Multiorgan Sarcoid-Like Reaction During Anti-PD-1 Treatment for Melanoma

Autor: Wouter W. van Willigen, Erik H.J.G. Aarntzen, Winald R. Gerritsen

Publikováno v: Clinical Nuclear Medicine, 44, 11, pp. 905-906
Clinical Nuclear Medicine, 44, 905-906

Contains fulltext : 208989.pdf (Publisher’s version ) (Open Access) We report a case of a 50-year-old woman treated with anti-PD-1 inhibition for metastatic melanoma. During treatment, extensive and transient histopathologically confirmed sarcoid-l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1650ae6170aff04d364cd2b7d6cd0d5f
https://hdl.handle.net/2066/208989

Critical headway estimation under uncertainty and non-ideal communication conditions

Autor: Leon Kester, J. F. C. M. de Jongh, W. van Willigen

Publikováno v: 2014 17th IEEE International Conference on Intelligent Transportation Systems, ITSC 2014, 320-327
ITSC

This article proposes a safety check extension to Adaptive Cruise Control systems where the critical headway time is estimated in real-time. This critical headway time estimate enables automated reaction to crisis circumstances such as when a precedi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4f91b69dceb01a1d4da0278d012c42
http://resolver.tudelft.nl/uuid:061ac708-85b2-4035-a22f-009bcf931ae3