Zobrazeno 1 - 10
of 166
pro vyhledávání: '"W. Wyrwich"'
Autor:
Natalie V. J. Aldhouse, Helen Kitchen, Chloe Johnson, Chris Marshall, Hannah Pegram, Sheryl Pease, Sam Collins, Christine L. Baker, Katherine Beaverson, Chandler Crews, Jill Massey, Kathleen W. Wyrwich
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-14 (2022)
Abstract Background This study aimed to identify fit-for-purpose clinical outcome assessments (COAs) to evaluate physical function, as well as social and emotional well-being in clinical trials enrolling a pediatric population with achondroplasia. Qu
Externí odkaz:
https://doaj.org/article/082b4920445d4264a6524fa4fff1daae
Autor:
Natalie V. J. Aldhouse, Helen Kitchen, Sarah Knight, Jake Macey, Fabio P. Nunes, Yves Dutronc, Natasha Mesinkovska, Justin M. Ko, Brett A. King, Kathleen W. Wyrwich
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 4, Iss 1, Pp 1-12 (2020)
Abstract Background Alopecia areata (AA) is characterized by hair loss that can affect the scalp and body. This study describes the psychosocial burden of AA. Methods Participants diagnosed with AA who had experienced ≥50% scalp hair loss according
Externí odkaz:
https://doaj.org/article/62e13393ca624abe952d13a7ebf07e94
Autor:
Louise Newton, Amy M. DeLozier, Philip C. Griffiths, Jennifer N. Hill, Stacie Hudgens, Tara Symonds, Jonathon C. Gable, Jim Paik, Kathleen W. Wyrwich, Lawrence F. Eichenfield, Linda Abetz-Webb, Jonathan I. Silverberg
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 3, Iss 1, Pp 1-12 (2019)
Abstract Background Atopic dermatitis (AD) is a common skin disorder characterized by chronic inflammation, altered skin barrier function, and inflammatory cell skin infiltration that decreases health-related quality of life (HRQoL). The study object
Externí odkaz:
https://doaj.org/article/32d1a2b495074b8f9ac3f17e1f886d0a
Autor:
Rebecca M. Speck, Huda Shalhoub, David W. Ayer, Janet H. Ford, Kathleen W. Wyrwich, Elizabeth N. Bush
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 3, Iss 1, Pp 1-9 (2019)
Abstract Purpose A concept elicitation, cognitive debriefing, and usability study was undertaken to: 1) ascertain the migraine experience with a particular focus on the impact on roles and daily functioning; 2) determine the comprehensiveness and com
Externí odkaz:
https://doaj.org/article/fa0c150ddede43ad91a5dec47132ca52
Autor:
Elizabeth D. Bacci, Amy M. DeLozier, Chen-Yen Lin, Carol L. Gaich, Terence Rooney, Richard Hoffman, Kathleen W. Wyrwich
Publikováno v:
Health and Quality of Life Outcomes, Vol 15, Iss 1, Pp 1-12 (2017)
Abstract Background To assess the measurement properties of two single-item patient-reported outcome (PRO) measures that assessed the length of time (in minutes) and severity of morning joint stiffness (MJS) experienced each day. Methods Data from tw
Externí odkaz:
https://doaj.org/article/8f0065e8f82a4d9388213817f1b528a5
Autor:
Elizabeth D. Bacci, Amy M. DeLozier, Chen-Yen Lin, Carol L. Gaich, Xiang Zhang, Terence Rooney, Stephanie de Bono, Richard Hoffman, Kathleen W. Wyrwich
Publikováno v:
Health and Quality of Life Outcomes, Vol 15, Iss 1, Pp 1-10 (2017)
Abstract Background To assess the reliability, validity, and responsiveness to treatment change of the single-item measure, Severity of Worst Tiredness, in patients with rheumatoid arthritis (RA). Methods Data from two Phase 3, randomized, placebo-co
Externí odkaz:
https://doaj.org/article/9971a7c116f24c3cbd0431ec7cf95874
Publikováno v:
Quality of Life Research. 32:1239-1246
Purpose: Anchor-based methods have been used to derive clinical outcome assessment (COA) interpretation thresholds of meaningful change over time for understanding individual (within-patient) as well as within-group change and between-group differenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f73709a71ef160d25a2cf05d310ea51
https://doi.org/10.1007/s11136-022-03297-7
https://doi.org/10.1007/s11136-022-03297-7
Autor:
Kathleen W. Wyrwich, Helen Kitchen, Sarah Knight, Natalie V. J. Aldhouse, Jake Macey, Natasha Mesinkovska, Justin M. Ko, Brett A. King
Publikováno v:
Quality of Life Research. 32:1319-1327
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6e970559acacef4e599433414c9ae16
https://doi.org/10.1007/s11136-022-03170-7
https://doi.org/10.1007/s11136-022-03170-7
Autor:
Karin S. Coyne, Brooke M. Currie, Michael Callaghan, Kathleen W. Wyrwich, Sheryl Pease, Christine L. Baker, Steven Arkin, Debra D. Pittman
Publikováno v:
European Journal of Haematology. 109:226-237
Individuals with sickle cell disease (SCD) experience vaso-occlusive crises (VOC). Historically, VOC episodes have been assessed through medical utilization, thereby excluding events managed at home. In order to validate a daily patient-reported outc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eb7f30f02c1b3c72f482401d4bdf223
https://doi.org/10.1111/ejh.13790
https://doi.org/10.1111/ejh.13790
Autor:
Kathleen W. Wyrwich PhD, Angela Schulz MD, Miriam Nickel MD, Peter Slasor ScD, Temitayo Ajayi MD, David R. Jacoby MD, PhD, Alfried Kohlschütter MD
Publikováno v:
Journal of Inborn Errors of Metabolism and Screening, Vol 6 (2018)
Neuronal ceroid lipofuscinosis type-2 (CLN2) disease is a rare, autosomal recessive, pediatric-onset, neurodegenerative lysosomal storage disease caused by mutations in the TPP1 gene. Cerliponase alfa (Brineura®), a recombinant form of human tripept
Externí odkaz:
https://doaj.org/article/7ca9a0296a2f40ffa5f003f65090402b