Zobrazeno 1 - 10 of 48 pro vyhledávání: '"W. Wirz"'
1
Expression and function of fibroblast growth factor (FGF) 9 in hepatic stellate cells and its role in toxic liver injury
Autor: Meltem Marvituna, Mathias Wycislo, P. Kiefer, Carmen G. Tag, Claus Hellerbrand, W. Wirz, Marianne Antoine, Axel M. Gressner
Publikováno v: Biochemical and Biophysical Research Communications. 361:335-341
Hepatic injury and regeneration of the liver are associated with activation of hepatic stellate cells (HSC). Fibroblast growth factors (FGFs) and their receptors are important regulators of repair in various tissues. HSC express FGFR3IIIc as well as
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::279c1927c74365e57da641c177800cac
https://doi.org/10.1016/j.bbrc.2007.06.189
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2
Fibroblast growth factor 16 and 18 are expressed in human cardiovascular tissues and induce on endothelial cells migration but not proliferation
Autor: R. Müller, Carmen G. Tag, W. Wirz, Axel M. Gressner, M. Antoine, M. Wycislo, P. Kiefer
Publikováno v: Biochemical and Biophysical Research Communications. 346:224-233
Endothelial cells line the blood vessel and precursor endothelial cells appear to have a pivotal effect on the organ formation of the heart, the embryonic development of the kidney, and the liver. Several growth factors including the fibroblast growt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a235d689164f76644ea033e88f456d
https://doi.org/10.1016/j.bbrc.2006.05.105
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3
Fibroblast growth factor 3, a protein with a dual subcellular fate, is interacting with human ribosomal protein S2
Autor: Kerstin Reimers, P. Kiefer, Axel M. Gressner, Marianne Antoine, R. Müller, W. Wirz
Publikováno v: Biochemical and Biophysical Research Communications. 338:1248-1255
The secreted isoform of fibroblast growth factor 3 (FGF3) induces a mitogenic cell response, while the nuclear form inhibits cell proliferation. Recently, we identified a nucleolar FGF3-binding protein which is implicated in processing of pre-rRNA as
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0b9b932f34dc70822c86ae146c6108
https://doi.org/10.1016/j.bbrc.2005.10.079
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4
On the origin of highly active biogeochemistry in deeper coastal sediments – inverse model studies
Autor: J. M. Holstein, K. W. Wirz
In coastal sediments, zones with highly active diagenesis may be situated below the usually studied first decimeters. Pore water profiles from a backbarrier tidal flat in the German Wadden Sea display a SO4 minimum zone associated with a distinct NH4
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::40cce3c7ca304f8144c7f8190d8cd17b
https://doi.org/10.5194/bgd-7-2065-2010
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5
Hepatic stellate cells display a functional vascular smooth muscle cell phenotype in a three-dimensional co-culture model with endothelial cells
Autor: T. Korff, Axel M. Gressner, Carmen G. Tag, M. Antoine, W. Wirz, P. Kiefer, Claus Hellerbrand
Publikováno v: Differentiation; research in biological diversity. 76(7)
Hepatic stellate cells (HSCs) are pericytes of liver sinusoidal endothelial cells (LSECs) and activation of HSC into a myofibroblast-like phenotype (called transdifferentiation) is involved in several hepatic disease processes including neovasculariz
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95041f222eaa594b01868d9c9fdfcb9f
https://pubmed.ncbi.nlm.nih.gov/18177423
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7
Upregulation of pleiotrophin expression in rat hepatic stellate cells by PDGF and hypoxia: implications for its role in experimental biliary liver fibrogenesis
Autor: I. Sawitza, Carmen G. Tag, Axel M. Gressner, M. Antoine, Erawan Borkham-Kamphorst, W. Wirz, P. Kiefer
Publikováno v: Biochemical and biophysical research communications. 337(4)
Pleiotrophin (PTN) is a secretory heparin binding protein with various biological activities including mitogenesis, angiogenesis, and tissue repair after injury. Recent studies have shown that PTN is a strong mitogen of hepatocytes and involved in li
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d42ad2cab138e295e7bc20266708f0
https://pubmed.ncbi.nlm.nih.gov/16226713
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8
Expression pattern of fibroblast growth factors (FGFs), their receptors and antagonists in primary endothelial cells and vascular smooth muscle cells
Autor: Axel M. Gressner, T. Korff, Carmen G. Tag, V Stoldt, W. Wirz, M. Antoine, M. Mavituna, N Emans, P. Kiefer
Publikováno v: Growth factors (Chur, Switzerland). 23(2)
Fibroblast growth factors (FGFs) are important angiogenic growth factors. While basic FGF (FGF2) is well established as a potent inducer of angiogenesis much less is known about other FGFs possibly expressed by EC. We investigated the expression of a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fa3f456e04f7861295104ff6113775f
https://pubmed.ncbi.nlm.nih.gov/16019430
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9
Identification of an unconventional nuclear localization signal in human ribosomal protein S2
Autor: Axel M. Gressner, W. Wirz, P. Kiefer, M. Antoine, R. Müller, Kerstin Reimers
Publikováno v: Biochemical and biophysical research communications. 335(1)
Ribosomal proteins must be imported into the nucleus after being synthesized in the cytoplasm. Since the rpS2 amino acid sequence does not contain a typical nuclear localization signal, we used deletion mutant analysis and rpS2-beta-galactosidase chi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3958cf108fe3aebf270de417e9f0999c
https://pubmed.ncbi.nlm.nih.gov/16061210
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