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pro vyhledávání: '"W. Weyenberg"'
Akademický článek
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Autor:
Erik Fransen, Arnout Everaert, W. Weyenberg, Annick Ludwig, Géraldine Broeckx, Filip Kiekens
Publikováno v:
International Journal of Pharmaceutics. 481:37-46
A novel drug delivery system (DDS) with sustained release properties was developed to allow ocular protein delivery. The DDS developed is aimed at overcoming stability issues during preparation such as denaturation of proteins caused by shear forces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a2c13a6abfec80c05960d8685e1db47
https://doi.org/10.1016/j.ijpharm.2015.01.042
https://doi.org/10.1016/j.ijpharm.2015.01.042
Autor:
Yannick Wouters, W. Weyenberg, Filip Kiekens, Annick Ludwig, Nadia Zakaria, Eline Melsbach, Arnout Everaert
Publikováno v:
International journal of pharmaceutics
A methodology was developed and optimised for the preparation of a new drug delivery system (DDS) with sustained release properties to allow ocular protein delivery and to limit destructive production steps during manufacturing. Elevated temperatures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b9aee35833504396bf029bc81da9c6
https://hdl.handle.net/10067/1457280151162165141
https://hdl.handle.net/10067/1457280151162165141
Autor:
W. Weyenberg, S.C. De Smedt, Roosmarijn E. Vandenbroucke, Marieke Vermeersch, Louis Maes, Annick Ludwig, Sandra Apers, Paul Cos, H. Van de Ven, A. Matheeussen
Publikováno v:
Journal of drug targeting
Drug delivery systems present an opportunity to potentiate the therapeutic effect of antileishmanial drugs. Colloidal carriers are rapidly cleared by the phagocytic cells of the reticuloendothelial system (RES), rendering them ideal vehicles for pass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cdeb85462f66153c76361f2fa975d9e
https://doi.org/10.3109/1061186x.2011.595491
https://doi.org/10.3109/1061186x.2011.595491
Autor:
J.P. Remon, S. Bozdag, Valentijn Vergote, Hans Nelis, Matthias D'Hondt, W. Weyenberg, K. De Prijck, Els Adriaens, Annick Ludwig, B. De Spiegeleer, Chris Vervaet
Publikováno v:
Drug development and industrial pharmacy
Objective: Ocular bioadhesive minitablets containing gentamicin and vancomycin were developed using different powder mixtures of pregelatinized starch and Carbopol (physical or cospray-dried mixtures). Methods: Drug content, antimicrobial activity, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9d24efeafe203aad1c6aad987d2a95
https://doi.org/10.3109/03639041003718030
https://doi.org/10.3109/03639041003718030
Publikováno v:
Journal of controlled release
The aim of the study was to develop a mucoadhesive ocular insert for the controlled delivery of ophthalmic drugs and to evaluate its efficacy in vivo. The inserts tested were based either on unmodified or thiolated poly(acrylic acid). Water uptake an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2eeb77584dfc83ed1f7e05169603258
https://doi.org/10.1016/s0168-3659(03)00135-4
https://doi.org/10.1016/s0168-3659(03)00135-4
Publikováno v:
Journal of controlled release
The influence of the compression force on the physical properties, the in vitro release and the in vivo behavior of ocular minitablets is evaluated in the present study. The bioerodible minitablets (O 2 mm, 6 mg) were produced at different compressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7fa1e356b5ee325829bda469543c165
https://doi.org/10.1016/s0168-3659(03)00130-5
https://doi.org/10.1016/s0168-3659(03)00130-5
Publikováno v:
Die Pharmazie. 69(1)
Cyclosporine A loaded poly(lactide-co-glycolide) nanoparticles were prepared using the o/w emulsification solvent evaporation method and the effect of four preparation parameters on particle size and zeta potential was investigated. Release propertie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f6f172c4102bc1f26ab7a70d4eb37991
https://pubmed.ncbi.nlm.nih.gov/24601220
https://pubmed.ncbi.nlm.nih.gov/24601220
Autor:
Annick Ludwig, Dave Van den Plas, Sabina Kerimova, W. Weyenberg, Peter Adriaensens, Robert Carleer, Kris Hermans
Publikováno v:
International journal of pharmaceutics
Ocular chitosan films were prepared in order to prolong ocular delivery of cyclosporine A. The mucoadhesive films were prepared using the solvent casting evaporation method. A 24 full factorial design was used to evaluate the effect of 4 preparation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc9bf39acfcf9907e6ef62f305f3797
https://hdl.handle.net/10067/1192120151162165141
https://hdl.handle.net/10067/1192120151162165141
Autor:
Caroline Paulussen, Pieterjan Kayaert, Paul Cos, A. Matheeussen, H. Van de Ven, Annick Ludwig, Patrick Rombaut, G. Van den Mooter, Pim-Bart Feijens, Louis Maes, W. Weyenberg
Publikováno v:
Journal of controlled release
This paper describes the development of poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles (NPs) and nanosuspensions with the polyene antibiotic amphotericin B (AmB). The nanoformulations were prepared using nanoprecipitation and were characterised
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882c010306d4cffa1822ca87fcda39f2
https://hdl.handle.net/10067/981030151162165141
https://hdl.handle.net/10067/981030151162165141