Zobrazeno 1 - 10
of 124
pro vyhledávání: '"W. W. Tourtellotte"'
Publikováno v:
The Journal of Neuroscience. 31:669-677
Extracellular matrix metalloproteinase inducer (EMMPRIN, CD147) is a member of the Ig superfamily, with various physiological roles including the induction of matrix metalloproteinases (MMPs), leukocyte activation, and tumor progression. In this stud
Publikováno v:
Neurology. 57:952-956
Objective: To evaluate the hypothesis that cyclooxygenase-2 (COX-2) is linked to the pathology of ALS by determining whether COX-2 mRNA levels are upregulated in ALS spinal cord. Methods: Spinal cord from 11 ALS cases and 27 controls consisting of 15
Autor:
H T, Agostini, C F, Ryschkewitsch, R W, Baumhefner, W W, Tourtellotte, E J, Singer, S, Komoly, G L, Stoner
Publikováno v:
Journal of neurovirology. 6
Two features of the biology of JC virus make it a particularly suitable candidate for an agent in MS-like disease: its neurotropic capability targeting glial cells as evidenced in progressive multifocal leukoencephalopathy lesions, and its capacity f
Publikováno v:
Neurology. 51(3)
The predictive value of CSF oligoclonal banding for the development of clinically definite MS (CDMS) within 5 years after optic neuritis was assessed in 76 patients enrolled in the Optic Neuritis Treatment Trial. The presence of oligoclonal bands was
Publikováno v:
Journal of the neurological sciences. 155(1)
The diagnostic significance of intrathecally synthesized IgG and virus-specific antibodies to measles, rubella and varicella-zoster (MRZ) in cerebrospinal fluid (CSF) remains controversial in cases of acute optic neuritis (AON). This study evaluates
Publikováno v:
Journal of medical virology. 52(3)
Human herpesvirus 6 (HHV-6), the etiologic agent of roseola in young children, has been reported to be detectable in the brain of many neurologically normal adults, although regional localization to plaques of multiple sclerosis has also been demonst
Autor:
D A, Aquino, E, Capello, J, Weisstein, V, Sanders, C, Lopez, W W, Tourtellotte, C F, Brosnan, C S, Raine, W T, Norton
Publikováno v:
Journal of neuropathology and experimental neurology. 56(6)
Recent studies have implicated heat shock proteins (HSP) in the pathogenesis of the multiple sclerosis (MS) lesion. Expression of the 73 kDa constitutive HSP (HSC70), the 72 kDa stress-inducible HSP (HSP70), and the 27 kDa small HSP (HSP27) was analy
Publikováno v:
Multiple sclerosis (Houndmills, Basingstoke, England). 2(3)
There remains controversy regarding the most sensitive and valid outcome assessments to use in multiple sclerosis (MS) clinical trials. A double blind, placebo controlled, parallel group multicenter clinical trial to evaluate the clinical efficacy of
Publikováno v:
Multiple sclerosis (Houndmills, Basingstoke, England). 1(4)
Thirty-seven chronic progressive multiple sclerosis (MS) patients, 20 of whom were taking cyclosporine, were examined for excretion of JC virus (JCV) in the urine. Polymerase chain reaction (PCR) amplification of DNA in urinary cell extracts detected
Autor:
Gerald L. Stoner, Elyse J. Singer, E. Licht, B. Fahy-Chandon, W. W. Tourtellotte, P. Singer, U. Tomiyasu
Publikováno v:
Acta neurologica Scandinavica. 90(6)
Progressive multifocal leukoencephalopathy (PML) due to JC virus can be the initial manifestation of AIDS. A 40-year-old man seropositive for HIV-1 presented with aphasia, hemiparesis, and hemianopsia, and with magnetic resonance imaging of the brain