Zobrazeno 1 - 10
of 142
pro vyhledávání: '"W. W. Nichols"'
Publikováno v:
Hereditas. 64:53-83
Polykaryocytosis was induced in human cells (Lu 106 cell line) grown on coverslips after treatment with high titer materials of the Edmonston strain of the measles virus. The nuclei in polykaryocytes exhibited cytopathic effects and were usually in c
Autor:
Tom Saldeen, Dayuan Li, Saeed R. Khan, Dani S. Zander, Sharon Weng, Jawahar L. Mehta, W. W. Nichols, Baichun Yang
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 19:378-383
Abstract —The mutant form of human apoA1, known as apoA1 Milano, is formed as a result of arginine 173 to cysteine substitution and inhibits experimental atherosclerosis in cholesterol-fed animals. This study was designed to determine if apoA1 Mila
Publikováno v:
European Journal of Anaesthesiology. 14:374-379
Remifentanil is an ultrashort acting mu opioid, well suited to total intravenous (i.v.) anaesthesia. Pain immediately following emergence from anaesthesia is a potential problem because of the rapid offset. This study investigated the transition from
Autor:
Jawahar L. Mehta, W. W. Nichols
Publikováno v:
Drugs. 40:657-665
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 258:H1402-H1408
To determine the contribution of thromboxane (Tx) A2 release in reperfusion injury, 17 dogs were subjected to total coronary occlusion for 1 h and reperfusion for 1 h. Eleven dogs were treated with saline, and six were treated with selective TxA2 syn
Autor:
B J, Ledwith, C L, Lanning, L A, Gumprecht, C A, Anderson, J B, Coleman, N T, Gatto, G, Balasubramanian, G M, Farris, R K, Kemp, L B, Harper, A B, Barnum, S J, Pacchione, K L, Mauer, P F J, Troilo, E R, Brown, J J, Wolf, J A, Lebronl, J A, Lewis, W W, Nichols
Publikováno v:
Developments in biologicals. 123
PER.C6, a cell line derived from human embryonic retinal cells transformed with the Adenovirus Type 5 (Ad5) E1A and E1B genes, is used to produce E1-deleted Ad5 vectors such as the MRKAd5 HIV-1 gag vaccine. While whole, live PER.C6 cells are capable
Autor:
B J, Ledwith, S, Manam, P J, Troilo, A B, Barnum, C J, Pauley, T G, Griffiths, L B, Harper, H B, Schock, H, Zhang, J E, Faris, P A, Way, C M, Beare, W J, Bagdon, W W, Nichols
Publikováno v:
Developments in biologicals. 104
The primary safety concern for DNA vaccines is their potential to integrate into host cellular DNA. We describe a sensitive and quantitative assay for investigating the tissue distribution and integration of plasmid DNA vaccines. By including gonadal
Publikováno v:
Molecular microbiology. 27(3)
The enzyme methylglyoxal synthase (MGS) was partially purified from Escherichia coli extracts, and the amino-terminal sequence of candidate proteins was determined, based on the native protein being a tetramer of about 69 kDa. Database analysis ident
Autor:
B D, Bertolet, L, Belardinelli, K, Avasarala, W B, Calhoun, E A, Franco, W W, Nichols, R A, Kerensky, J A, Hill
Publikováno v:
Cardiovascular research. 32(5)
To determine the relative sensitivity of cardiac A1- and A2-adenosine receptor-mediated effects to antagonism by theophylline in man.Baseline measurements of the A-H interval (A1-adenosine receptor-mediated effect) and coronary blood flow (A2-adenosi
Publikováno v:
Cancer research. 56(14)
Peroxisome proliferators (PPs) are a diverse group of nongenotoxic rodent liver carcinogens. One potential mechanism for the carcinogenicity of PPs is epigenetic modulation of growth-regulatory signal transduction pathways. We investigated the effect