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pro vyhledávání: '"W. Todd Penberthy"'
Autor:
W. Todd Penberthy
Publikováno v:
PPAR Research, Vol 2009 (2009)
Acute attacks of multiple sclerosis (MS) are most commonly treated with glucocorticoids, which can provide life-saving albeit only temporary symptomatic relief. The mechanism of action (MOA) is now known to involve induction of indoleamine 2,3-dioxyg
Externí odkaz:
https://doaj.org/article/b2bfd688603f4cf9b8873ecd052885b3
Autor:
W. Todd Penberthy, James B. Kirkland
Publikováno v:
Present Knowledge in Nutrition. :293-306
Publikováno v:
Cellular and Molecular Life Sciences
Primate theta-defensins are physically distinguished as the only known fully-cyclic peptides of animal origin. Humans do not produce theta-defensin peptides due to a premature stop codon present in the signal sequence of all six theta-defensin pseudo
Publikováno v:
The EPMA Journal
Type 1 diabetes (T1D) is an autoimmune disease in which a T-cell-mediated reaction demolishes insulin-producing cells of pancreatic islets. Inadequacy of insulin therapy has motivated research focused on mechanisms by which autoimmune reactions can b
Autor:
Boris Görg, Noora Shahbeck, Khalid Ibrahim, Johannes Häberle, Tawfeg Ben-Omran, Dieter Häussinger, Martin Stucki, Liyan Hu, W. Todd Penberthy, Farrukh A. Chaudhry, Michele Frapolli
Publikováno v:
Journal of inherited metabolic disease. 38(6)
Glutamine synthetase (GS) deficiency is an ultra-rare inborn error of amino acid metabolism that has been described in only three patients so far. The disease is characterized by neonatal onset of severe encephalopathy, low levels of glutamine in blo
Autor:
Nigel G. F. Cooper, Huifang Sun, Julie B. Schuck, W. Todd Penberthy, Xiaohong Li, Michael E. Smith
Publikováno v:
BMC Neuroscience
BMC Neuroscience, Vol 12, Iss 1, p 88 (2011)
BMC Neuroscience, Vol 12, Iss 1, p 88 (2011)
BackgroundUnlike mammals, teleost fishes are capable of regenerating sensory inner ear hair cells that have been lost following acoustic or ototoxic trauma. Previous work indicated that immediately following sound exposure, zebrafish saccules exhibit
Autor:
W Todd, Penberthy
Publikováno v:
Current pharmaceutical design. 15(1)
Autor:
W. Todd Penberthy
Publikováno v:
PPAR Research
PPAR Research, Vol 2009 (2009)
PPAR Research, Vol 2009 (2009)
Acute attacks of multiple sclerosis (MS) are most commonly treated with glucocorticoids, which can provide life-saving albeit only temporary symptomatic relief. The mechanism of action (MOA) is now known to involve induction of indoleamine 2,3-dioxyg
Autor:
W. Todd Penberthy
Publikováno v:
Current drug metabolism. 8(3)
Cells at the maternal-fetal interface express indoleamine 2,3 dioxygenase (IDO) to consume all local tryptophan for the express purpose of starving adjacent maternal T cells of this most limiting and essential amino acid. This stops local T cell prol
Publikováno v:
Nature immunology. 4(12)
The zebrafish is firmly established as a genetic model for the study of vertebrate blood development. Here we have characterized the blood-forming system of adult zebrafish. Each major blood lineage can be isolated by flow cytometry, and with these l