Výsledky vyhledávání - "W. Todd Penberthy"

Akademický článek

Nicotinic Acid-Mediated Activation of Both Membrane and Nuclear Receptors towards Therapeutic Glucocorticoid Mimetics for Treating Multiple Sclerosis

Autor: W. Todd Penberthy

Publikováno v: PPAR Research, Vol 2009 (2009)

Acute attacks of multiple sclerosis (MS) are most commonly treated with glucocorticoids, which can provide life-saving albeit only temporary symptomatic relief. The mechanism of action (MOA) is now known to involve induction of indoleamine 2,3-dioxyg

Externí odkaz: https://doaj.org/article/b2bfd688603f4cf9b8873ecd052885b3

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Niacin

Autor: W. Todd Penberthy, James B. Kirkland

Publikováno v: Present Knowledge in Nutrition. :293-306

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6a5708c1bfc32acfd922d8d7c96f2357
https://doi.org/10.1002/9781119946045.ch19

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Retrocyclins and their activity against HIV-1

Autor: Alexander M. Cole, Amy L. Cole, W. Todd Penberthy, Soumya Chari

Publikováno v: Cellular and Molecular Life Sciences

Primate theta-defensins are physically distinguished as the only known fully-cyclic peptides of animal origin. Humans do not produce theta-defensin peptides due to a premature stop codon present in the signal sequence of all six theta-defensin pseudo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91fcb53b0f694512f96b986cfd0dc256

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The potential role of indoleamine 2,3 dioxygenase (IDO) as a predictive and therapeutic target for diabetes treatment: a mythical truth

Autor: Babak Baban, Mahmood S. Mozaffari, W. Todd Penberthy

Publikováno v: The EPMA Journal

Type 1 diabetes (T1D) is an autoimmune disease in which a T-cell-mediated reaction demolishes insulin-producing cells of pancreatic islets. Inadequacy of insulin therapy has motivated research focused on mechanisms by which autoimmune reactions can b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead8b033d6bd5cb37f71a0261d198cda
http://europepmc.org/articles/PMC3405305

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Secondary NAD+ deficiency in the inherited defect of glutamine synthetase

Autor: Boris Görg, Noora Shahbeck, Khalid Ibrahim, Johannes Häberle, Tawfeg Ben-Omran, Dieter Häussinger, Martin Stucki, Liyan Hu, W. Todd Penberthy, Farrukh A. Chaudhry, Michele Frapolli

Publikováno v: Journal of inherited metabolic disease. 38(6)

Glutamine synthetase (GS) deficiency is an ultra-rare inborn error of amino acid metabolism that has been described in only three patients so far. The disease is characterized by neonatal onset of severe encephalopathy, low levels of glutamine in blo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8d51f05cc8aac2d5ef4189ba645501
https://pubmed.ncbi.nlm.nih.gov/25896882

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Transcriptomic analysis of the zebrafish inner ear points to growth hormone mediated regeneration following acoustic trauma

Autor: Nigel G. F. Cooper, Huifang Sun, Julie B. Schuck, W. Todd Penberthy, Xiaohong Li, Michael E. Smith

Publikováno v: BMC Neuroscience
BMC Neuroscience, Vol 12, Iss 1, p 88 (2011)

BackgroundUnlike mammals, teleost fishes are capable of regenerating sensory inner ear hair cells that have been lost following acoustic or ototoxic trauma. Previous work indicated that immediately following sound exposure, zebrafish saccules exhibit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf85de54b2995fb161715971ee7b9f2f
https://pubmed.ncbi.nlm.nih.gov/21888654

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