Zobrazeno 1 - 10
of 359
pro vyhledávání: '"W. Timothy Garvey"'
Publikováno v:
Obesity Science & Practice, Vol 10, Iss 3, Pp n/a-n/a (2024)
Abstract Background Anti‐obesity medications (AOMs) have historically had limited weight‐loss efficacy. However, newer glucagon‐like peptide‐1 receptor agonist (GLP‐1 RA)–based therapies seem to be more effective, including dual agonists
Externí odkaz:
https://doaj.org/article/14e2bc0e80c5425c99e6b0c9950d24c0
Autor:
Samantha L. Martin, Li Zhang, Makenzie L. Callahan, Jessica Bahorski, Cora E. Lewis, Bertha A. Hidalgo, Nefertiti Durant, Lorie M. Harper, Ashley N. Battarbee, Kirk Habegger, Bethany A. Moore, Alysha Everett, Stella Aslibekyan, Rogerio Sertie, Nengjun Yi, W. Timothy Garvey, Paula Chandler‐Laney
Publikováno v:
Obesity Science & Practice, Vol 8, Iss 5, Pp 627-640 (2022)
Abstract Objective Obesity in pregnancy and gestational diabetes (GDM) increase cardiometabolic disease risk but are difficult to disentangle. This study aimed to test the hypothesis that 4–10 years after a pregnancy complicated by overweight/obesi
Externí odkaz:
https://doaj.org/article/4365fadc781842c4a7c34111d95c913a
Autor:
Jeanne M. Clark, W. Timothy Garvey, Kevin D. Niswender, Ann Marie Schmidt, Rexford S. Ahima, Jose O. Aleman, Ashley N. Battarbee, Joshua Beckman, Wendy L. Bennett, Nancy J. Brown, Paula Chandler‐Laney, Nancy Cox, Ira J. Goldberg, Kirk M. Habegger, Lorie M. Harper, Alyssa H. Hasty, Bertha A. Hidalgo, Sangwon F. Kim, Julie L. Locher, James M. Luther, Nisa M. Maruthur, Edgar R. Miller, Mary Ann Sevick, Quinn Wells
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 4 (2023)
ABSTRACT: As the worldwide prevalence of overweight and obesity continues to rise, so too does the urgency to fully understand mediating mechanisms, to discover new targets for safe and effective therapeutic intervention, and to identify biomarkers t
Externí odkaz:
https://doaj.org/article/dfc5fe5313eb46eda04ed5b4b43b5df4
Autor:
Subodh Verma, Meena Bhatta, Melanie Davies, John E. Deanfield, W. Timothy Garvey, Camilla Jensen, Kristian Kandler, Robert F. Kushner, Domenica M. Rubino, Mikhail N. Kosiborod
Publikováno v:
EClinicalMedicine, Vol 55, Iss , Pp 101737- (2023)
Summary: Background: Inflammation is a key driver of atherosclerotic cardiovascular disease. C-reactive protein (CRP), an established biomarker of inflammation, is commonly elevated in people with overweight/obesity. Methods: STEP 1, 2, and 3 were 68
Externí odkaz:
https://doaj.org/article/60feb89664bd496d9129a6ab9fd90750
Autor:
Alicia J. Jenkins, Barbara H. Braffett, Arpita Basu, Ionut Bebu, Samuel Dagogo-Jack, Trevor J. Orchard, Amisha Wallia, Maria F. Lopes-Virella, W. Timothy Garvey, John M. Lachin, Timothy J. Lyons, the DCCT/EDIC Research Group
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract In type 2 diabetes, hyperuricemia is associated with cardiovascular disease (CVD) and the metabolic syndrome (MetS), but associations in type 1 diabetes (T1D) have not been well-defined. This study examined the relationships between serum ur
Externí odkaz:
https://doaj.org/article/f9fee4388877495b97606fb3d560869c
Publikováno v:
Metabolites, Vol 12, Iss 12, p 1226 (2022)
A known association exists between exposure to gestational diabetes mellitus (GDM) and epigenetic age acceleration (EAA) in GDM-exposed offspring compared to those without GDM exposure. This association has not been assessed previously in mothers wit
Externí odkaz:
https://doaj.org/article/c24a6225187c435eaf35c053ac417571
Autor:
Gordon Fisher, Jeannie Tay, Jonathan L. Warren, W. Timothy Garvey, Ceren Yarar‐Fisher, Barbara A. Gower
Publikováno v:
Physiological Reports, Vol 9, Iss 19, Pp n/a-n/a (2021)
Abstract Objective Insulin sensitivity is lower in African American (AA) versus Caucasian American (CA). We tested the hypothesis that lower insulin sensitivity in AA could be explained by mitochondrial respiratory rates, coupling efficiency, myofibe
Externí odkaz:
https://doaj.org/article/81cfc2a201da42cfbe5fad6ea746c9ed
Autor:
Arpita Basu, Ionut Bebu, Alicia J. Jenkins, Julie A. Stoner, Ying Zhang, Richard L. Klein, Maria F. Lopes-Virella, W. Timothy Garvey, Matthew J. Budoff, Petar Alaupovic, Timothy J. Lyons
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 8, Pp 1432-1439 (2019)
APOB, APOC3, and APOE and apolipoprotein-defined lipoprotein subclasses (ADLSs; based on qualitative apolipoprotein complement) have been associated with dyslipidemia and CVD. Our main objective was to define associations of serum apolipoproteins and
Externí odkaz:
https://doaj.org/article/57fe2509e4d54794a7abcabf30c50e57
Autor:
Richard A. Miller, David E. Harrison, David B. Allison, Molly Bogue, Lucas Debarba, Vivian Diaz, Elizabeth Fernandez, Andrzej Galecki, W. Timothy Garvey, Hashan Jayarathne, Navasuja Kumar, Martin A. Javors, Warren C. Ladiges, Francesca Macchiarini, James Nelson, Peter Reifsnyder, Nadia A. Rosenthal, Marianna Sadagurski, Adam B. Salmon, Daniel L. Smith Jr., Jessica M. Snyder, David B. Lombard, Randy Strong
Publikováno v:
JCI Insight, Vol 5, Iss 21 (2020)
Canagliflozin (Cana) is an FDA-approved diabetes drug that protects against cardiovascular and kidney diseases. It also inhibits the sodium glucose transporter 2 by blocking renal reuptake and intestinal absorption of glucose. In the context of the m
Externí odkaz:
https://doaj.org/article/8346a43abd5742d2afbdcea95b0aa4d1
Autor:
Dmitry Grapov, Oliver Fiehn, Caitlin Campbell, Carol J. Chandler, Dustin J. Burnett, Elaine C. Souza, Gretchen A. Casazza, Nancy L. Keim, Gary R. Hunter, Jose R. Fernandez, W. Timothy Garvey, Charles L. Hoppel, Mary‐Ellen Harper, John W. Newman, Sean H. Adams
Publikováno v:
Physiological Reports, Vol 8, Iss 17, Pp n/a-n/a (2020)
Abstract Very little is known about how metabolic health status, insulin resistance or metabolic challenges modulate the endocannabinoid (eCB) or polyunsaturated fatty acid (PUFA)‐derived oxylipin (OxL) lipid classes. To address these questions, pl
Externí odkaz:
https://doaj.org/article/f939dd25011c4530ad740512e0645637