Zobrazeno 1 - 7
of 7
pro vyhledávání: '"W. Thomas Leach"'
Publikováno v:
International Journal of Pharmaceutics. 423:264-280
Agitation of small amounts of liquid is performed routinely in biopharmaceutical process, formulation, and packaging development. Protein degradation commonly results from agitation, but the specific stress responsible or degradation mechanism is usu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a23c7567a80f2df03c442ead244a8ba
https://doi.org/10.1016/j.ijpharm.2011.11.044
https://doi.org/10.1016/j.ijpharm.2011.11.044
Encapsulation of protein nanoparticles into uniform-sized microspheres formed in a spinning oil film
Autor:
Kwon Taek Lim, Eun Jeong Park, Dale T. Simpson, Zhongshui Yu, W. Thomas Leach, Keith P. Johnston, Tibisay N. Val, Robert O. Williams
Publikováno v:
AAPS PharmSciTech. 6:E605-E617
A new spinning oil film (SOF) solid-in-oil-in-oil emulsion process was developed to produce uniform-sized protein-loaded biodegradable microspheres. A thin SOF on a cylindrical rotor was used to shear droplets from a nozzle tip to control droplet siz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c82fe150717f723dcf5b43c8e6774d9
https://doi.org/10.1208/pt060475
https://doi.org/10.1208/pt060475
Autor:
Keith P. Johnston, Robert O. Williams, Tibisay N. Val, Zhongshui Yu, Efemona C. Anuta, Dale T. Simpson, W. Thomas Leach
Publikováno v:
Journal of Pharmaceutical Sciences. 94:56-69
Stable protein nanostructured particles, produced by spray freezing into liquid (SFL) nitrogen, were encapsulated uniformly into microspheres to reduce the burst release over the first 24 h. The denaturation and aggregation of these bovine serum albu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ac0ae399063153773dc028cf88fbe2
https://doi.org/10.1002/jps.20209
https://doi.org/10.1002/jps.20209
Publikováno v:
Journal of Applied Physics. 92:4695-4698
High-density (>1×1012 cm−2) Si nanoparticles have been successfully grown on Si3N4 and SiO2 thin films by hot-wire chemical vapor deposition (HW-CVD) using disilane, in which Si atoms are generated on a heated tungsten filament and, after desorbin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0044566c76ae1966781be8760c138be2
https://doi.org/10.1063/1.1509841
https://doi.org/10.1063/1.1509841
Publikováno v:
Journal of Crystal Growth. 243:30-40
Silicon nanoparticles are grown via ultra high vacuum chemical vapor deposition (UHV-CVD) on SiO 2 and Si 3 N 4 covered Si(1 0 0) substrates using disilane. Temperature programmed desorption spectra demonstrate the presence of H 2 and SiO desorption
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::057d54bbb11bd3dacbad7dad475d6770
https://doi.org/10.1016/s0022-0248(02)01472-0
https://doi.org/10.1016/s0022-0248(02)01472-0
Publikováno v:
Journal of Crystal Growth. 240:415-422
Deposition of sub-monolayer silicon on SiO 2 /Si(1 0 0) greatly facilitates nucleation in subsequent thermal chemical vapor deposition (CVD) of silicon nanoparticles. Sub-monolayer seeding is accomplished using silicon atoms generated via disilane de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e24b8f3851623227b31c58127b5749cf
https://doi.org/10.1016/s0022-0248(02)01076-x
https://doi.org/10.1016/s0022-0248(02)01076-x
Publikováno v:
MRS Proceedings. 704
A non-thermal method to facilitate nucleation for subsequent thermal chemical vapor deposition of Si nanoparticles on SiO2/Si(001) with high density and uniform size is demonstrated. Submonolayers of Si adatoms are predeposited on SiO2/Si(001) substr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42d92ead0b40ca78fdf350d6fcaaa34f
https://doi.org/10.1557/proc-704-w10.10.1
https://doi.org/10.1557/proc-704-w10.10.1