Zobrazeno 1 - 10
of 89
pro vyhledávání: '"W. Theunissen"'
Autor:
W. Theunissen, D. Fanni, S. Nemolato, E. Di Felice, T. Cabras, C. Gerosa, P. Van Eyken, I. Messana, M. Castagnola, G. Faa
Publikováno v:
European Journal of Histochemistry, Vol 58, Iss 1 (2014)
Thymosin beta 4 (Tβ4) and thymosin beta 10 (Tβ10) are two members of the beta-thymosin family involved in many cellular processes such as cellular motility, angiogenesis, inflammation, cell survival and wound healing. Recently, a role for beta-thym
Externí odkaz:
https://doaj.org/article/1948c84333b945d298169cab9324affb
Autor:
Mingyue Guo, Jinyi Wu, Chuanxin Chen, Xinggu Wang, An Gong, Wei Guan, Rowan M. Karvas, Kexin Wang, Mingwei Min, Yixuan Wang, Thorold W. Theunissen, Shaorong Gao, José C. R. Silva
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Human naïve pluripotent stem cells (hnPSCs) can generate integrated models of blastocysts termed blastoids upon switch to inductive medium. However, the underlying mechanisms remain obscure. Here we report that self-renewing hnPSCs spontane
Externí odkaz:
https://doaj.org/article/1c3913050d6f4fae83b1d163a97c7142
Autor:
Robert Morey, Tony Bui, Virginia Chu Cheung, Chen Dong, Joseph E. Zemke, Daniela Requena, Harneet Arora, Madeline G. Jackson, Donald Pizzo, Thorold W. Theunissen, Mariko Horii
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109569- (2024)
Summary: Preeclampsia (PE) is a hypertensive pregnancy disorder with increased risk of maternal and fetal morbidity and mortality. Abnormal extravillous trophoblast (EVT) development and function is considered to be the underlying cause of PE, but ha
Externí odkaz:
https://doaj.org/article/dd20a5899562403fa7defa0b04b10da9
Autor:
Xin Huang, Kyoung-mi Park, Paul Gontarz, Bo Zhang, Joshua Pan, Zachary McKenzie, Laura A. Fischer, Chen Dong, Sabine Dietmann, Xiaoyun Xing, Pavel V. Shliaha, Jihong Yang, Dan Li, Junjun Ding, Tenzin Lungjangwa, Maya Mitalipova, Shafqat A. Khan, Sumeth Imsoonthornruksa, Nick Jensen, Ting Wang, Cigall Kadoch, Rudolf Jaenisch, Jianlong Wang, Thorold W. Theunissen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Although the interactors of pluripotency factors have been identified in mouse embryonic stem cells (ESCs), their interactors in human ESCs remain unexplored. Here the authors map OCT4 protein interactions in naïve and primed human ESCs to find spec
Externí odkaz:
https://doaj.org/article/475ca4c998cb484bb6963209f6ebdc13
Autor:
Shafqat A. Khan, Kyoung-mi Park, Laura A. Fischer, Chen Dong, Tenzin Lungjangwa, Marta Jimenez, Dominick Casalena, Brian Chew, Sabine Dietmann, Douglas S. Auld, Rudolf Jaenisch, Thorold W. Theunissen
Publikováno v:
Cell Reports, Vol 35, Iss 11, Pp 109233- (2021)
Summary: Naive human embryonic stem cells (hESCs) have been isolated that more closely resemble the pre-implantation epiblast compared to conventional “primed” hESCs, but the signaling principles underlying these discrete stem cell states remain
Externí odkaz:
https://doaj.org/article/0ab0294c046a4f59a6b32af4c1a272a8
Autor:
Chen Dong, Mariana Beltcheva, Paul Gontarz, Bo Zhang, Pooja Popli, Laura A Fischer, Shafqat A Khan, Kyoung-mi Park, Eun-Ja Yoon, Xiaoyun Xing, Ramakrishna Kommagani, Ting Wang, Lilianna Solnica-Krezel, Thorold W Theunissen
Publikováno v:
eLife, Vol 9 (2020)
Naïve human pluripotent stem cells (hPSCs) provide a unique experimental platform of cell fate decisions during pre-implantation development, but their lineage potential remains incompletely characterized. As naïve hPSCs share transcriptional and e
Externí odkaz:
https://doaj.org/article/675d04b3a8644c879266a76954cb9721
Autor:
Isabel Lam, Alain Ndayisaba, Amanda J. Lewis, YuHong Fu, Giselle T. Sagredo, Ludovica Zaccagnini, Jackson Sandoe, Ricardo L. Sanz, Aazam Vahdatshoar, Timothy D. Martin, Nader Morshed, Toru Ichihashi, Arati Tripathi, Nagendran Ramalingam, Charlotte Oettgen-Suazo, Theresa Bartels, Max Schäbinger, Erinc Hallacli, Xin Jiang, Amrita Verma, Challana Tea, Zichen Wang, Hiroyuki Hakozaki, Xiao Yu, Kelly Hyles, Chansaem Park, Thorold W. Theunissen, Haoyi Wang, Rudolf Jaenisch, Susan Lindquist, Beth Stevens, Nadia Stefanova, Gregor Wenning, Kelvin C. Luk, Rosario Sanchez Pernaute, Juan Carlos Gómez-Esteban, Daniel Felsky, Yasujiro Kiyota, Nidhi Sahni, S. Stephen Yi, Chee-Yeun Chung, Henning Stahlberg, Isidro Ferrer, Johannes Schöneberg, Stephen J. Elledge, Ulf Dettmer, Glenda M. Halliday, Tim Bartels, Vikram Khurana
Intracellular inclusions accompanying neurodegeneration are histopathologically and ultrastructurally heterogeneous but the significance of this heterogeneity is unclear. iPSC models, while promising for disease modeling, do not form inclusions in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c012494b212921233507969b33cb45f
https://doi.org/10.1101/2022.11.08.515615
https://doi.org/10.1101/2022.11.08.515615
Publikováno v:
Dermatologic Surgery. 47:1185-1189
BACKGROUND The role of Mohs micrographic surgery (MMS) in the management of melanoma of the head and neck (HNM) has been controversial. The authors systematically reviewed the local recurrence rate of melanoma in situ (MIS) and T1a melanomas using MM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8352e9ce8daa66758be5791ddeecbb7
https://doi.org/10.1097/dss.0000000000003126
https://doi.org/10.1097/dss.0000000000003126
Publikováno v:
Cellular and molecular life sciences : CMLS. 79(12)
Trophoblasts are specialized epithelial cells that perform critical functions during blastocyst implantation and mediate maternal-fetal communication during pregnancy. However, our understanding of human trophoblast biology remains limited since acce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29fd2f49de36fac6ed1a4a3ac15a785e
https://pubmed.ncbi.nlm.nih.gov/36434136
https://pubmed.ncbi.nlm.nih.gov/36434136
Autor:
Chen Dong, Thorold W. Theunissen
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619070
Methods Mol Biol
Methods Mol Biol
The placenta is a transient organ that mediates the exchange of nutrients, gases, and waste products between the mother and the developing fetus and is indispensable for a healthy pregnancy. Epithelial cells in the placenta, which are termed trophobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b21014855b78110bcbc9834ec32a28
https://doi.org/10.1007/978-1-0716-1908-7_7
https://doi.org/10.1007/978-1-0716-1908-7_7