Zobrazeno 1 - 10
of 149
pro vyhledávání: '"W. Tew"'
Autor:
B. Ditz, J. Boekhoudt, N. Couto, C. A. Brandsma, P. S. Hiemstra, G. W. Tew, M. Neighbors, M. A. Grimbaldeston, W. Timens, H. A. M. Kerstjens, J. W. A. Rossen, V. Guryev, M. van den Berge, A. Faiz
Publikováno v:
COPD, Vol 19, Iss 1, Pp 81-87 (2022)
Current knowledge about the respiratory microbiome is mainly based on 16S ribosomal RNA gene sequencing. Newer sequencing approaches, such as metatranscriptomics, offer the technical ability to measure the viable microbiome response to environmental
Externí odkaz:
https://doaj.org/article/749e08c21c9a4d66a6a98a0ac95bfe09
Autor:
Margaret Neighbors, Qingling Li, Sha (Joe) Zhu, Jia Liu, Weng Ruh Wong, Guiquan Jia, Wendy Sandoval, Gaik W. Tew
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 6, Pp 100375- (2023)
Idiopathic pulmonary fibrosis (IPF) is a progressive disease with significant mortality. Prognostic biomarkers to identify rapid progressors are urgently needed to improve patient management. Since the lysophosphatidic acid (LPA) pathway has been imp
Externí odkaz:
https://doaj.org/article/6495128bfe724bb1ae4121a00cd0aaff
Autor:
Qingling Li, Weng Wong, Andrew Birnberg, Arindam Chakrabarti, Xiaoying Yang, David F. Choy, Julie Olsson, Erik Verschueren, Margaret Neighbors, Wendy Sandoval, Carrie M. Rosenberger, Michele A. Grimbaldeston, Gaik W. Tew
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Chronic obstructive pulmonary disease (COPD) exacerbations are heterogenous and profoundly impact the disease trajectory. Bioactive lipid lysophosphatidic acid (LPA) has been implicated in airway inflammation but the significance
Externí odkaz:
https://doaj.org/article/fb00e03d0f8641e9bbfca8c9c870db5b
Autor:
Elise M. A. Slob, Alen Faiz, Jos vanNijnatten, Susanne J. H. Vijverberg, Cristina Longo, Merve Kutlu, Fook Tim Chew, Yang Yie Sio, Esther Herrera‐Luis, Antonio Espuela‐Ortiz, Javier Perez‐Garcia, Maria Pino‐Yanes, Esteban G. Burchard, Uroš Potočnik, Mario Gorenjak, Colin Palmer, Cyrielle Maroteau, Steve Turner, Katia Verhamme, Leila Karimi, Somnath Mukhopadhyay, Wim Timens, Pieter S. Hiemstra, Mariëlle W. Pijnenburg, Margaret Neighbors, Michele A. Grimbaldeston, Gaik W. Tew, Corry A. Brandsma, Vojko Berce, Hananeh Aliee, Fabian Theis, Don D. Sin, Xuan Li, Maarten van denBerge, Anke H. Maitland‐van der Zee, Gerard H. Koppelman
Publikováno v:
Clinical and Translational Allergy, Vol 12, Iss 8, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/aad33376d38744ce9d92723e7fc44c1d
Autor:
Arindam Chakrabarti, Jordan S. Mar, David F. Choy, Yi Cao, Nisha Rathore, Xiaoying Yang, Gaik W. Tew, Olga Li, Prescott G. Woodruff, Christopher E. Brightling, Michele Grimbaldeston, Stephanie A. Christenson, Mona Bafadhel, Carrie M. Rosenberger
Publikováno v:
ERJ Open Research, Vol 7, Iss 3 (2021)
Introduction COPD exacerbations are heterogeneous and can be triggered by bacterial, viral, or noninfectious insults. Exacerbations are also heterogeneous in neutrophilic or eosinophilic inflammatory responses. A noninvasive peripheral biomarker of C
Externí odkaz:
https://doaj.org/article/692862264ef245069cba5c9438c1380c
Autor:
Benedikt Ditz, Jeunard G. Boekhoudt, Hananeh Aliee, Fabian J. Theis, Martijn Nawijn, Corry-Anke Brandsma, Pieter S. Hiemstra, Wim Timens, Gaik W. Tew, Michele A. Grimbaldeston, Margaret Neighbors, Victor Guryev, Maarten van den Berge, Alen Faiz
Publikováno v:
ERJ Open Research, Vol 7, Iss 2 (2021)
Externí odkaz:
https://doaj.org/article/5bebb9ea5ee9414d8bed32f6738661c0
Autor:
Kasia Owczarczyk, Matthew D. Cascino, Cecile Holweg, Gaik W. Tew, Ward Ortmann, Timothy Behrens, Thomas Schindler, Carol A. Langford, E. William St. Clair, Peter A. Merkel, Robert Spiera, Philip Seo, Cees G.M. Kallenberg, Ulrich Specks, Noha Lim, John Stone, Paul Brunetta, Marco Prunotto, the RAVE-ITN Research Group
Publikováno v:
JCI Insight, Vol 5, Iss 18 (2020)
BACKGROUND Baseline expression of FCRL5, a marker of naive and memory B cells, was shown to predict response to rituximab (RTX) in rheumatoid arthritis. This study investigated baseline expression of FCRL5 as a potential biomarker of clinical respons
Externí odkaz:
https://doaj.org/article/b7bd1818f0e642e5849a9f696ba49b07
Autor:
O. A. Carpaij, F. O. W. Muntinghe, M. B. Wagenaar, J. W. Habing, W. Timens, H. A. M. Kerstjens, M. C. Nawijn, L. I. Z. Kunz, P. S. Hiemstra, G. W. Tew, C. T. J. Holweg, C. A. Brandsma, M. van den Berge
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-5 (2018)
Abstract Although Th2 driven inflammation is present in COPD, it is not clearly elucidated which COPD patients are affected. Since periostin is associated with Th2 driven inflammation and inhaled corticosteroid (ICS)-response in asthma, it could func
Externí odkaz:
https://doaj.org/article/8436ae2bd15947cb99c5c4dfb31db15b
Autor:
Arindam Chakrabarti, Xiaoying Yang, Qingling Li, Margaret Neighbors, Erik Verschueren, Julie Olsson, Andrew Birnberg, Carrie M. Rosenberger, Weng Wong, Michele A. Grimbaldeston, Wendy Sandoval, David F. Choy, Gaik W. Tew
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-12 (2021)
Background Chronic obstructive pulmonary disease (COPD) exacerbations are heterogenous and profoundly impact the disease trajectory. Bioactive lipid lysophosphatidic acid (LPA) has been implicated in airway inflammation but the significance of LPA in
Autor:
Michele A. Grimbaldeston, Arindam Chakrabarti, Yi Cao, Nisha Rathore, Stephanie A. Christenson, Prescott G. Woodruff, Xiaoying Yang, Jordan S. Mar, Christopher E. Brightling, David F. Choy, Olga Li, Mona Bafadhel, Carrie M. Rosenberger, Gaik W. Tew
Publikováno v:
ERJ Open Research. :00836-2020
IntroductionCOPD exacerbations are heterogeneous and can be triggered by bacterial, viral, or non-infectious insults. Exacerbations are also heterogeneous in neutrophilic or eosinophilic inflammatory responses. A non-invasive peripheral biomarker of