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pro vyhledávání: '"W. T. Thach"'
Autor:
W. T. Thach
Publikováno v:
The Cerebellum. 13:139-150
Opinion is divided on what the exact function of the cerebellum is. Experiments are summarized that support the following views: (1) the cerebellum is a combiner of multiple movement factors; (2) it contains anatomically fixed permanent focal represe
Autor:
W. T. Thach
Publikováno v:
The Cerebellum. 6:163-167
The cerebellum is highly stereotyped in its cellular circuitry. Output neurons in the nuclei with one exception excite their downstream targets in other parts of the nervous system. Yet the much more voluminous cerebellar cortex inhibits these output
Publikováno v:
Experimental Brain Research. 146:511-522
We examined how cerebellar deficits in isolated reaching or grasping movements contribute to abnormalities in a combined reach and grasp movement, and whether people with cerebellar damage show abnormalities in the spatiotemporal relationships of rea
Publikováno v:
Journal of Neurophysiology. 83:3019-3030
Prior work has shown that cerebellar subjects have difficulty adjusting for interaction torques that occur during multi-jointed movements. The purpose of this study was to determine whether this deficit is due to a general inability to generate suffi
Autor:
W. T. Thach
Publikováno v:
Behavioral and Brain Sciences. 19:411-433
Brindley proposed that we initially generate movements “consciously”, under higher cerebral control. As the movement is practiced, the cerebellum learns to link within itself the context in which the movement is made to the lower level movement g
Publikováno v:
Brain. 119:1199-1211
Human subjects threw balls of clay at a visual target while looking through wedge prism spectacles. In studies of short-term adjustment, subjects threw in the direction of their prism-bent gaze, missing the target to that side. Within 10-30 throws, t
Autor:
Amy J. Bastian, W. T. Thach
Publikováno v:
Annals of Neurology. 38:881-892
Previous work has shown that lesions in the lateral cerebellum involving the dentate nucleus impair both reaching and pinching movements in humans and monkeys. This study addressed the question of whether disruption of the cerebellar-thalamo-cortical
Autor:
W. T. Thach, Jeffrey G. Keating
Publikováno v:
Journal of Neurophysiology. 73:1329-1340
1. Complex spikes of cerebellar Purkinje cells recorded from awake, behaving monkeys were studied to determine the extent to which their discharge could be quantified as periodic. Three Rhesus monkeys were trained to perform up to five different task
Publikováno v:
Annual Review of Neuroscience. 15:403-442
Based on a review of cerebellar anatomy, neural discharge in relation to behavior, and focal ablation syndromes, we propose a model of cerebellar function that we believe is both comprehensive as to the available information (at these levels) and uni
Autor:
Jonathan W. Mink, W. T. Thach
Publikováno v:
Journal of Neurophysiology. 65:273-300
1. To evaluate the various hypotheses that the basal ganglia preferentially control one mode of movement to the exclusion of others, we recorded the discharge of single neurons in the globus pallidus (GP) in rhesus monkeys during their performance of