Zobrazeno 1 - 10 of 61 pro vyhledávání: '"W. T. ROBINSON"'
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β-(1,10-Phenanthroline)(1,3-propanediamine-N,N'-diacetato)cobalt(III) Chloride Trihydrate
Autor: W. T. Robinson, Shane G. Telfer, Richard M. Hartshorn
Publikováno v: Acta Crystallographica Section C Crystal Structure Communications. 53:1757-1759
The crystal structure of [Co(C 7 H 12 N 2 O 4 )(C 12 H 8 N 2 )]-Cl.3H 2 O is the first reported structure of a cobalt complex with the tetradentate 1,3-propanediamine-N,N'-diacetato ligand and it has adopted a β unsymmetrical cis configuration. The
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::81f3085c679baae1be9f3173a99a056c
https://doi.org/10.1107/s0108270197010755
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3
The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin: effect on human cytochrome P-450 and implications for metabolic drug interactions
Autor: V, Fischer, L, Johanson, F, Heitz, R, Tullman, E, Graham, J P, Baldeck, W T, Robinson
Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 27(3)
Fluvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, was metabolized by human liver microsomes to 5-hydroxy-, 6-hydroxy-, and N-deisopropyl-fluvastatin. Total metabolite formation was biphasic with apparent Km values of 0.2 to 0.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c3e7633284065eb70e15e973536e9d12
https://pubmed.ncbi.nlm.nih.gov/10064574
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6
Pharmacokinetics of fluvastatin and specific drug interactions
Autor: H T Smith, W T Robinson, L A Jokubaitis, A J Troendle, D S Hwang
Publikováno v: American journal of hypertension. 6(11 Pt 2)
Fluvastatin sodium (Lescol) is the first synthetic 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)-reductase inhibitor to be studied extensively in humans. Absorption of fluvastatin is complete and unaffected by the presence of food. Systemic exposur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a653d5fb9da7782bc7cc16507b13f4b
https://pubmed.ncbi.nlm.nih.gov/8297546
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8
Single- vs multiple-dose pharmacokinetics of clozapine in psychiatric patients
Autor: M G, Choc, F, Hsuan, G, Honigfeld, W T, Robinson, L, Ereshefsky, M L, Crismon, S R, Saklad, J, Hirschowitz, R, Wagner
Publikováno v: Pharmaceutical research. 7(4)
Clozapine plasma levels were monitored in 16 patients during a series of three consecutive treatments (single dose-multiple dose-single dose). Each patient received a single 75-mg dose (3 x 25 mg) with clozapine tablets, and serial plasma samples wer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::153fdab83695e846f89d6d7164bcc084
https://pubmed.ncbi.nlm.nih.gov/2194198
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