Výsledky vyhledávání - "W. T. J. M. Hekkens"

Grain prolamins; why immunogenic, how toxic?

Autor: W. T. J. M. Hekkens, M. van Twist-de Graaf

Publikováno v: Inflammatory Bowel Disease and Coeliac Disease in Children ISBN: 9789401073240

Grain prolamins play a decisive role in the aetiology of coeliac disease. What is the special make-up of these prolamins to interfere with the intestinal lining in people with a genetic constitution that makes them sensitive to these molecules? This

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7edd83c1d91d543187057b16dc13a9dc
https://doi.org/10.1007/978-94-009-1850-4_14

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Lysosomal damage by gliadin and gliadin peptides; An activity not related to coeliac disease

Autor: W. T. J. M. Hekkens, F W M de Rooij, C. P. M. Van Den Aarsen

Publikováno v: Clinica Chimica Acta. 91:127-131

Rat-liver lysosomes have been used to determine the toxicity of gliadin fractions in relation to coeliac disease. In this study we compared the activity in acid phosphatase release from rat-liver lysosomes by casein, gliadin and by their peptic-trypt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8495157438e4a69a679efe66590491cd
https://doi.org/10.1016/0009-8981(79)90446-7

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Alpha gliadin antibody levels: a serological test for coeliac disease

Autor: Conleth Feighery, Alan J. Thompson, W. T. J. M. Hekkens, Jacinta Kelly, B Bradley, D. G. Weir, Cliona O'Farrelly

Publikováno v: BMJ. 286:2007-2010

The diagnostic value in coeliac disease of circulating antibodies to casein, crude gliadin, and alpha gliadin was assessed using an adaption of the enzyme linked immunosorbent assay system. alpha Gliadin was the only antigen which consistently separa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5536dcc4f26f4024fe10f1828c222574
https://doi.org/10.1136/bmj.286.6383.2007

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Monoclonal antibodies reacting with gliadin as tools for assessing antigenic structure responsible for exacerbation of celiac disease

Autor: S. Stoyanov, Helena Tlaskalova-Hogenova, W. T. J. M. Hekkens, H. Kristofova, Přemysl Frič, Petr Kocna

Publikováno v: Immunology Letters. 17:335-338

Monoclonal antibodies reactive with gliadin were prepared by fusion of spleen cells isolated from gliadin-immunized BALB/c mice with myeloma cells. The reactivity of mAbs with different preparations of gliadin and their enzymatic digest were measured

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a196137fa59548151c82cdff38a6121
https://doi.org/10.1016/0165-2478(88)90007-7

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The determination of ammonium in kjeldahl digests using the gas-sensing ammonia electrode. Comparison of the direct method with the known-addition method

Autor: J. P. Giliams, M. Nube, C. P. M. Van Den Aarsen, W. T. J. M. Hekkens

Publikováno v: Clinica Chimica Acta. 100:239-244

The efficacy of the ammonia electrode for analysis of the nitrogen content of a large series of Kjeldahl digests was investigated. By using this electrode, two methods for the measurement of ammonium concentrations were compared, the direct method an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93beff6f52cfa0d4b2efe354850acb5d
https://doi.org/10.1016/0009-8981(80)90272-7

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The specificity of wheat protein reactivity in coeliac disease

Autor: W. T. J. M. Hekkens, Cliona O'Farrelly, Donald G. Weir, Conleth Feighery

Publikováno v: Scandinavian journal of gastroenterology. 18(5)

The purpose of this study was to compare the effects of seven wheat protein fractions on the cell-mediated immune response of coeliac patients and normal individuals, by means of the leukocyte migration inhibition factor (LMIF) assay. Two preparation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c06cf0d1c89026556164f3ae93799d72
https://pubmed.ncbi.nlm.nih.gov/6372068

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