Zobrazeno 1 - 10
of 137
pro vyhledávání: '"W. Stäubli"'
Autor:
W.L. Bencze, M.E. Dempsey, S. Eisenberg, J.M. Felts, I.D. Frantz, R. Hess, D. Kritchevsky, R.I. Levy, T.A. Miettinen, L.L. Rudel, H.S. Sodhi, W. Stäubli, T. Zempl, &AAe, nyi
The major cause of death in the Western world is some form of vascular disease; and principal among these forms is atherosclerotic heart disease (ASHD). Although much is known about the etiology and treatment of ASHD, there is, as yet, no specific me
Autor:
Albert G. Burger, W. Stäubli, Cristiana E. Juge-Aubry, S. Muakkassah-Kelly, Anne-Lise Krinke, Wojciech Malinowski, F. Waechter, Philip Bentley
Publikováno v:
Toxicology and Applied Pharmacology. 107:129-140
Male rats were fed triethyleneglycol-bis-3(3-tert-butyl-4-hydroxy-5-methyl)propionate (TK 12627) admixed with the food at a concentration of 1000 ppm for 3, 6, 13, and 20 days. Treatment resulted in time-dependent and marked increases in serum levels
Autor:
Philip Bentley, J. Suter, Elspeth M. Jack, W. Stäubli, S. Muakkassah-Kelly, F. Waechter, F. Bieri, Luis M. Cruz-Orive
Publikováno v:
Scopus-Elsevier
Gamma-glutamyltranspeptidase-positive hepatocyte foci were produced in female rats given a single dose of diethylnitrosamine neonatally after birth and, after weaning, a diet containing phenobarbitone for 30 wk. The nucleator method, a new stereologi
Publikováno v:
Toxicology in Vitro. 4:428-431
Peroxisome proliferation in rodents is associated with hepatocarcinogenicity. This association has led to increased interest in the phenomenon and to the search for in vitro tests to detect peroxisome proliferators and to study the mechanisms by whic
Autor:
E.M. Jack, Philip Bentley, W. Stäubli, J. Suter, F. Waechter, F. Bieri, S. Muakkassah-Kelly, Luis-Manuel Cruz-Orive
Publikováno v:
Scopus-Elsevier
Jack, E.M.; Stäubli, W.; Waechter, F.; Bentley, P.; Suter, J.; Bieri, F.; Muakkassah-Kelly, S.F.; Cruz-Orive, Luis-Manuel (1990). Ultrastructural changes in chemically induced preneoplastic focal lesions in the rat liver: a stereological study. Carcinogenesis, 11(9), pp. 1531-1538. Oxford University Press 10.1093/carcin/11.9.1531
Jack, E.M.; Stäubli, W.; Waechter, F.; Bentley, P.; Suter, J.; Bieri, F.; Muakkassah-Kelly, S.F.; Cruz-Orive, Luis-Manuel (1990). Ultrastructural changes in chemically induced preneoplastic focal lesions in the rat liver: a stereological study. Carcinogenesis, 11(9), pp. 1531-1538. Oxford University Press 10.1093/carcin/11.9.1531
Ultrastructural changes were investigated and quantified, using a stereological approach, in early gamma-glutamyltranspeptidase (GGT)-positive focal lesions, induced in the rat liver by treatment with a single initiating dose of diethylnitrosamine (D
Autor:
Peter Sagelsdorff, F. Waechter, Victor Meier, W. Stäubli, S. Muakkassah-Kelly, F. Bieri, Philip Bentley
Publikováno v:
Biochemical pharmacology. 41(2)
The amount of the two mRNAs although lower in cultured hepatocytes than in freshly isolated cells was found to be rapidly inducible upon the addition of 32 microM nafenopin. The induction of cyt.P452 mRNA always preceded the induction of PBE mRNA, bu
Autor:
Samar M. Kelly, F. Waechter, Peter Sagelsdorff, Philip Bentley, Daniel Ebner, W. Stäubli, F. Bieri, Peter Dollenmeier
Publikováno v:
Toxicology letters. 50(2-3)
[ 14 C] di -n- octyltin dichloride ([14C]DOTC) was administered by oral gavage to male and female rats. After 96 h hepatic and thymic DNA was isolated. All DNA fractions were radioactive, but analysis of DNA hydrolysates by HPLC revealed that the rad
Autor:
F. Waechter, F. Bieri, M. Nelly Morales, Ariel Orellana, W. Stäubli, Philip Bentley, Miguel Bronfman
Publikováno v:
Biochemical and Biophysical Research Communications. 159:1026-1031
Acyl-Coenzyme A thioesters of the hypolipidaemic and cancerinogenic peroxisome proliferators clofibric acid, nafenopin, ciprofibrate, bezafibrate and tibric acid were found to greatly increase the activity of rat brain protein kinase C. Maximal activ
Publikováno v:
Pathophysiology of Haemostasis and Thrombosis. 8:149-157
Endothelial regeneration was studied in rabbit aorta after intra-arterial balloon catheterization. Most of the regenerated endothelium originated from existing branches which was assessed by the Evans-blue uptake pattern and confirmed by transmission
Publikováno v:
The Journal of Cell Biology
The repeated administration of the hypolipidemic agent Su-13 437 (nafenopin) to neonatal rats roughly doubled the number of peroxisomes in the liver tissue and caused a sixfold volumetric expansion of the peroxisomal compartment. During the prolifera