Výsledky vyhledávání

Abstract 6135: Dynamics of ligand-induced epidermal growth factor receptor internalization in cancer cell lines

Autor: Mandy W. Smeets, Eef F. Smits, Janneke J. Melis, Dimitri Pappaioannou, Guido J. Zaman

Publikováno v: Cancer Research. 83:6135-6135

Antibody-drug conjugates (ADCs), comprised of cancer cell-specific antibodies linked to cytotoxic drugs, represent an innovative and promising class of anticancer agents. Due to its amplified expression in various tumor types, the epidermal growth fa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37a077dc46a2b62eb5d6a78c348dcd70
https://doi.org/10.1158/1538-7445.am2023-6135

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Can the PROPER intervention reduce psychotropic drug prescription in nursing home residents with dementia? Results of a cluster-randomized controlled trial

Autor: Debby L. Gerritsen, Raymond T.C.M. Koopmans, Claudia H. W. Smeets, Martin Smalbrugge, K. van der Spek, Marjorie H. J. M. G. Nelissen-Vrancken, Steven Teerenstra, Sytse U Zuidema

Publikováno v: International Psychogeriatrics, 33(6). Cambridge University Press
Smeets, C H W, Smalbrugge, M, Koopmans, R T C M, Nelissen-Vrancken, M H J M G, Van Der Spek, K, Teerenstra, S, Gerritsen, D L & Zuidema, S U 2021, ' Can the PROPER intervention reduce psychotropic drug prescription in nursing home residents with dementia? Results of a cluster-randomized controlled trial ', International Psychogeriatrics, vol. 33, no. 6, pp. 577-586 . https://doi.org/10.1017/S1041610220000629
International Psychogeriatrics, 33(6), 577-586. Cambridge University Press
International Psychogeriatrics, 33, 6, pp. 577-586
International psychogeriatrics / IPA, 33(6), 577-586. Cambridge University Press
International Psychogeriatrics, 33, 577-586

Objectives:To evaluate the effect of the PROPER intervention in nursing home residents with dementia on the prevalence of psychotropic drug use and neuropsychiatric symptoms.Design:A cluster-randomized controlled design with two parallel groups (inte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4567d252e7e2c9be6892cfb78d009a69
https://hdl.handle.net/2066/234982

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The effects of long-term open-air fumigation with SO

Autor: M J, Kropff, J, Mooi, J, Goudriaan, W, Smeets, A, Leemans, C, Kliffen

Publikováno v: The New phytologistreferences. 113(3)

Faba bean crops (Vicia faba L.) were exposed to elevated SO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1aef37e52a2fbae223d4c7106ac8ca26
https://pubmed.ncbi.nlm.nih.gov/33874193

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Implementing a multidisciplinary psychotropic medication review among nursing home residents with dementia: a process evaluation

Autor: Klaas van der Spek, Raymond T.C.M. Koopmans, Sytse U Zuidema, Martin Smalbrugge, Claudia H. W. Smeets, Debby L. Gerritsen, Erica de Vries

Publikováno v: International Psychogeriatrics, 33, 933-945
International Psychogeriatrics. Cambridge University Press
International psychogeriatrics / IPA, 1-13. Cambridge University Press
STARTPAGE=1;ENDPAGE=13;ISSN=1041-6102;TITLE=International psychogeriatrics / IPA
International Psychogeriatrics, 33, 9, pp. 933-945
Gerritsen, D L, de Vries, E, Smalbrugge, M, Smeets, C H W, van der Spek, K, Zuidema, S U & Koopmans, R T C M 2019, ' Implementing a multidisciplinary psychotropic medication review among nursing home residents with dementia: A process evaluation ', International Psychogeriatrics . https://doi.org/10.1017/S1041610219000577
International Psychogeriatrics, 33(9), 933-945. Cambridge University Press

Objectives:Before drawing conclusions on the contribution of an effective intervention to daily practice and initiating dissemination, its quality and implementation in daily practice should be optimal. The aim of this process evaluation was to study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477b5883a9dff6e07be1559cca6c8c3e
http://hdl.handle.net/2066/245455

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Efficacy of antipsychotics in dementia depended on the definition of patients and outcomes

Autor: Debby L. Gerritsen, Sytse U Zuidema, Raymond T.C.M. Koopmans, M. Smalbrugge, Tessa A. Hulshof, C H W Smeets, Hendrika J Luijendijk

Publikováno v: Journal of Clinical Epidemiology, 101, pp. 17-27
Smeets, C H W, Zuidema, S U, Hulshof, T A, Smalbrugge, M, Gerritsen, D L, Koopmans, R T C M & Luijendijk, H J 2018, ' Efficacy of antipsychotics in dementia depended on the definition of patients and outcomes: a meta-epidemiological study ', Journal of Clinical Epidemiology, vol. 101, pp. 17-27 . https://doi.org/10.1016/j.jclinepi.2018.05.004
Journal of Clinical Epidemiology, 101, 17-27

Item does not contain fulltext OBJECTIVES: Postulating that efficacy of antipsychotics for agitation and psychosis in dementia is best estimated in trials among patients with these symptoms and with symptom-specific outcomes, we investigated whether

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f51a5b86d698e64c99f149531f355e5e
https://doi.org/10.1016/j.jclinepi.2018.05.004

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Blood gas sample spiking with total parenteral nutrition, lipid emulsion, and concentrated dextrose solutions as a model for predicting sample contamination based on glucose result

Autor: Steven W. Smeets, Jose C Jara-Aguirre, Amy M. Wockenfus, Brad S. Karon

Publikováno v: Clinical Biochemistry. 55:93-95

Objective Evaluate the effects of blood gas sample contamination with total parenteral nutrition (TPN)/lipid emulsion and dextrose 50% (D50) solutions on blood gas and electrolyte measurement; and determine whether glucose concentration can predict b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de9f7a803c74443d3663a7bc8c99ca3
https://doi.org/10.1016/j.clinbiochem.2018.03.011

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The effect of biannual medication reviews on the appropriateness of psychotropic drug use for neuropsychiatric symptoms in patients with dementia: a randomised controlled trial

Autor: Raymond T.C.M. Koopmans, Claudia H. W. Smeets, Roland B Wetzels, Erica de Vries, Klaas van der Spek, Sytse U Zuidema, Debby L. Gerritsen, Martin Smalbrugge, Marjorie H. J. M. G. Nelissen-Vrancken, Steven Teerenstra

Publikováno v: Age and Ageing, 47, 3, pp. 430-437
Age and Ageing, 47(3), 430-437. Oxford University Press
Age and Ageing, 47, 430-437
van der Spek, K, Koopmans, R T C M, Smalbrugge, M, Nelissen-Vrancken, M H J M G, Wetzels, R B, Smeets, C H W, Vries, E D, Teerenstra, S, Zuidema, S U & Gerritsen, D L 2018, ' The effect of biannual medication reviews on the appropriateness of psychotropic drug use for neuropsychiatric symptoms in patients with dementia: A randomised controlled trial ', Age and Ageing, vol. 47, no. 3, pp. 430-437 . https://doi.org/10.1093/ageing/afy001

Objective: We studied the efficacy of biannual structured medication reviews to improve the appropriateness of psychotropic drug (PD) prescriptions for neuropsychiatric symptoms (NPS) in nursing home patients with dementia.Study Design and Setting: I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc5c9dc2fae55aa6211a707d6ab0e15a
https://hdl.handle.net/2066/191666

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Factors associated with appropriate psychotropic drug prescription in nursing home patients with severe dementia

Autor: Debby L. Gerritsen, Sytse U Zuidema, Raymond T.C.M. Koopmans, Marjorie H. J. M. G. Nelissen-Vrancken, Steven Teerenstra, Klaas van der Spek, Martin Smalbrugge, Roland B Wetzels, Claudia H. W. Smeets

Publikováno v: International Psychogeriatrics, 1-10. Cambridge University Press
STARTPAGE=1;ENDPAGE=10;ISSN=1041-6102;TITLE=International Psychogeriatrics
International Psychogeriatrics, 30, 4, pp. 547-556
International Psychogeriatrics, 30, 547-556
International Psychogeriatrics, 30(4), 547-556. Cambridge University Press
van der Spek, K, Koopmans, R TCM, Smalbrugge, M, Nelissen-Vrancken, M HJMG, Wetzels, R B, Smeets, C HW, Teerenstra, S, Zuidema, S U & Gerritsen, D L 2017, ' Factors associated with appropriate psychotropic drug prescription in nursing home patients with severe dementia ', International Psychogeriatrics, pp. 1-10 . https://doi.org/10.1017/S1041610217001958

Background:We studied the patient and non-patients factors of inappropriate psychotropic drug (PD) prescription for neuropsychiatric symptoms (NPS) in nursing home patients with severe dementia.Methods:In a cross-sectional study, the appropriateness

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8e471c6f00c33e8b6511fc7b8d5f30
https://doi.org/10.1017/S1041610217001958

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A reliable and valid index was developed to measure appropriate psychotropic drug use in dementia

Autor: Debby L. Gerritsen, Claudia H. W. Smeets, Martin Smalbrugge, Raymond T.C.M. Koopmans, Roland B Wetzels, Klaas van der Spek, Sytse U Zuidema, Marjorie H. J. M. G. Nelissen-Vrancken

Publikováno v: Journal of Clinical Epidemiology, 68(8), 903-912. Elsevier USA
Journal of Clinical Epidemiology, 68, 903-12
van der Spek, K, Gerritsen, D L, Smalbrugge, M, Nelissen-Vrancken, M H J M, Wetzels, R B, Smeets, C H W, Zuidema, S U & Koopmans, R T C M 2015, ' A reliable and valid index was developed to measure appropriate psychotropic drug use in dementia ', Journal of Clinical Epidemiology, vol. 68, no. 8, pp. 903-912 . https://doi.org/10.1016/j.jclinepi.2015.03.012
Journal of Clinical Epidemiology, 68(8), 903-912. ELSEVIER SCIENCE INC
Journal of Clinical Epidemiology, 68, 8, pp. 903-12

Objectives: The aim of this study was to develop an index derived from the Medication Appropriateness Index (MAT) items that is suited for clinical studies evaluating appropriateness of psychotropic drug use (PDU) for neuropsychiatric symptoms (NPS)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce06cd6334f285aba25f33244f4afd15
https://doi.org/10.1016/j.jclinepi.2015.03.012

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