Zobrazeno 1 - 10
of 32
pro vyhledávání: '"W. Scott Webster"'
Publikováno v:
Baylor University Medical Center Proceedings. 32:579-581
Urachal carcinoma is a highly uncommon malignancy with an estimated prevalence of 0.01% to 0.02% of all adult cancers. Due to its rarity, no standardized management protocol for urachal cancer has been developed. Surgery is often the main therapeutic
Autor:
John C. Cheville, R. Houston Thompson, Michael L. Blute, Christine M. Lohse, Bradley C. Leibovich, W. Scott Webster
Publikováno v:
Urology. 70:900-904
OBJECTIVES Previous observations suggest that cystic clear cell renal cell carcinoma (RCC) is cured with surgical resection. However, long-term outcome data are lacking. We reviewed our experience with RCC and report on pathologic features and patien
Publikováno v:
Urology. 68:1042-1045
Objectives As the population ages, healthy octogenarians are increasingly diagnosed with prostate cancer. Some of these patients will request radical prostatectomy (RP), although outcome data in this population group are lacking. We report our experi
Autor:
John C. Cheville, Eugene D. Kwon, Demetrius Dicks, Shomik Sengupta, R. Houston Thompson, Christine M. Lohse, Haidong Dong, Bradley C. Leibovich, Xavier Frigola, W. Scott Webster, Igor Frank, Michael L. Blute
Publikováno v:
Cancer. 107:46-53
BACKGROUND The impact of mononuclear cell infiltration on renal cell carcinoma (RCC) biology has been controversial, previously reported to be associated with either a favorable or unfavorable prognosis. The objective of the current study was to eval
Autor:
Christine M. Lohse, Haidong Dong, Bradley C. Leibovich, Eugene D. Kwon, Lieping Chen, Horst Zincke, Michael D. Gillett, Michael L. Blute, W. Scott Webster, John C. Cheville, R. Houston Thompson
Publikováno v:
Cancer. 104:2084-2091
Cancer cell expression of costimulatory molecule B7-H1 has been implicated as a potent inhibitor of T-cell-mediated antitumoral immunity. The authors recently reported that B7-H1 is aberrantly expressed in primary renal cell carcinoma (RCC). Blockade
Publikováno v:
Journal of Clinical Oncology. 23:8262-8269
A number of recently developed and promising approaches to antitumoral immunotherapy are being investigated as potential treatments for advanced prostate cancer. These approaches largely revolve around strategies to increase antigen-specific T-cell a
Autor:
R. Houston Thompson, Bradley C. Leibovich, Horst Zincke, Michael L. Blute, John C. Cheville, Igor Frank, W. Scott Webster, Christine M. Lohse, Eugene D. Kwon
Publikováno v:
Journal of Urology. 174:1218-1221
Purpose: Perinephric and renal sinus fat invasion are classified as pT3a renal cell carcinoma (RCC) according to the 2002 American Joint Committee on Cancer. We investigated the prognostic significance of each of these pathological features using a c
Autor:
Brant A. Inman, Xavier Frigola, Kimberley J. Harris, Susan M. Kuntz, Haidong Dong, R. Houston Thompson, W. Scott Webster
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 179(5)
Development of effective vaccination approaches to treat established tumors represents a focus of intensive research because such approaches offer the promise of enhancing immune system priming against tumor Ags via restimulation of pre-existing (mem
Autor:
Bradley C. Leibovich, Amy E. Krambeck, Haidong Dong, Christopher J. Krco, Christine M. Lohse, Keith L. Knutson, Xavier Frigola, John C. Cheville, Michael L. Blute, Sandra Bonne-Annee, Susan M. Kuntz, Shomik Sengupta, Eugene D. Kwon, Maria Mercader, W. Scott Webster, Sameer Siddiqui
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 13(7)
Purpose: Regulatory T cells (Tregs) have been implicated as inhibitors of antitumoral immunity, and evidence suggests that elimination of Tregs may augment natural and pharmacologic immunity. We tested for the presence of putative Tregs within renal
Autor:
Thomas J. Sebo, W. Scott Webster, Michael L. Blute, Horst Zincke, Christine M. Lohse, Alexander S. Parker, Susan M. Kuntz, John C. Cheville, Haidong Dong, Igor Frank, Shomik Sengupta, R. Houston Thompson, Eugene D. Kwon, Bradley C. Leibovich
Publikováno v:
Cancer research. 66(7)
B7-H1 participates in T-cell costimulation functioning as a negative regulator of immunity. Recent observations suggest that B7-H1 is expressed by renal cell carcinoma (RCC) tumor cells and is associated with poor prognosis. However, outcome analyses