Zobrazeno 1 - 10
of 129
pro vyhledávání: '"W. Schoene"'
Publikováno v:
Nutrition Research. 72:57-69
Resveratrol (Res), a natural polyphenol compound found in grapes and red wine, has been shown to exhibit anti-inflammatory, antioxidant, and anticarcinogenic effects. However, proinflammatory/tumor-promoting properties of Res have also been reported,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a5026b84bd58f7e974b34c918b8f0d
https://doi.org/10.1016/j.nutres.2019.10.003
https://doi.org/10.1016/j.nutres.2019.10.003
Autor:
Jiawei Wan, Thomas T.Y. Wang, Yanbei Wu, Qiang He, Norberta W. Schoene, Liangli Yu, Quynhchi Pham, Bin Li, Uyory Choe
Publikováno v:
Annual Review of Food Science and Technology. 10:389-408
Understanding the relationship between food and the gut microbiota, their interactions, and how each modulates the other is critical for successful promotion of human health. This review seeks to summarize ( a) the current knowledge on the effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17da6af61b157821870783fd21d05d1
https://doi.org/10.1146/annurev-food-032818-121303
https://doi.org/10.1146/annurev-food-032818-121303
Publikováno v:
Molecular Carcinogenesis. 51:244-256
In the present studies, we utilized prostate cancer cell culture models to elucidate the mechanisms of action of broccoli-derived phytochemicals 3,3′-diindolylmethane (DIM) and indole-3-carbinol (I3C). We found DIM and I3C at 1–5 µM inhibited an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb11d85a9d97544f8d885a0fa5aa3924
https://doi.org/10.1002/mc.20774
https://doi.org/10.1002/mc.20774
Publikováno v:
Experimental Biology and Medicine. 235:932-940
Zinc is an essential nutrient for humans; however, this study demonstrated for the first time that an elevated zinc status, created by culturing cells at optimal plasma zinc concentration attainable by oral zinc supplementation, is cytotoxic for norm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd923aa9d0edce5a14be0390d0060f6
https://doi.org/10.1258/ebm.2010.010076
https://doi.org/10.1258/ebm.2010.010076
Publikováno v:
Journal of Biological Chemistry. 285:12055-12062
Selenium chemoprevention by apoptosis has been well studied, but it is not clear whether selenium can activate early barriers of tumorigenesis, namely senescence and DNA damage response. To test this hypothesis, we treated normal and cancerous cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774d42722869a254066c6159eaecf10f
https://doi.org/10.1074/jbc.m109.088781
https://doi.org/10.1074/jbc.m109.088781
Publikováno v:
American Journal of Physiology-Cell Physiology. 297:C1188-C1199
Phosphorylated Akt (p-Akt), a phosphoinositide-3-OH-kinase-activated protein kinase, is highly expressed in prostate tumors. p-Akt can indirectly hinder p53-dependent growth suppression and apoptosis by phosphorylating Mdm2. Alternatively, p-Akt can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a742195c3ecc09f114e67f40070856a
https://doi.org/10.1152/ajpcell.00042.2009
https://doi.org/10.1152/ajpcell.00042.2009
Publikováno v:
American Journal of Physiology-Cell Physiology. 294:C1342-C1349
The involvement of p53 and p21 signal pathway in the G2/M cell cycle progression of zinc-supplemented normal human bronchial epithelial (NHBE) cells was examined using the small interferring RNA (siRNA) approach. Cells were cultured for one passage i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d6b8980f9f7ceec0e15feb70c89eb95
https://doi.org/10.1152/ajpcell.00061.2008
https://doi.org/10.1152/ajpcell.00061.2008
Publikováno v:
Experimental Biology and Medicine. 233:317-327
An adequate zinc status is essential for optimal cellular functions and growth. Yet, excessive zinc supplementation can be cytotoxic and can impair cell growth. Gadd45 plays a vital role as cellular stress sensor in the modulation of cell signal tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4fd25c76f00b4cd434090a8acc6584
https://doi.org/10.3181/0708-rm-220
https://doi.org/10.3181/0708-rm-220
Autor:
Kai Y. Lei, Norberta W. Schoene, Chung-Ting Han, Stephen H. K. Wong, Rita S. M. Shih, Yangqing Zhao
Publikováno v:
American Journal of Physiology-Cell Physiology. 292:C2175-C2184
The influence of zinc status on p21 gene expression was examined in human hepatoblastoma (HepG2) cells. Cells were cultured for one passage in a basal medium depleted of zinc to induce severely zinc-deficient (ZD) cells or in basal medium supplemente
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76df948226a31bc9205daf5c71230927
https://doi.org/10.1152/ajpcell.00256.2006
https://doi.org/10.1152/ajpcell.00256.2006
Publikováno v:
Experimental Biology and Medicine. 231:611-618
The influence of zinc status on the expression of proteins known to be involved in the stability of p53, the human tumor suppressor gene product, was examined in hepatoblastoma (HepG2) cells. Cells were cultured in zinc-deficient (ZD0.2, ZD0.4), zinc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa971e299081465a1f50858b4ba14104
https://doi.org/10.1177/153537020623100516
https://doi.org/10.1177/153537020623100516