Zobrazeno 1 - 10
of 77
pro vyhledávání: '"W. Schmid-Burgk"'
Publikováno v:
Acta Psychiatrica Scandinavica. 92:260-265
The efficacy and the safety of moclobemide (400-600 mg/day), a reversible and selective inhibitor of monoamine oxidase-A (RIMA) and of clomipramine (100-150 mg/day) were compared respectively in 98 and 93 nonmelancholic, nonpsychotic out-patients wit
Publikováno v:
Clinical Neuropharmacology. 17:S74-S87
Safety aspects [adverse events, blood pressure and heart rate, weight, and laboratory tests (liver parameters, hemoglobin, leukocytes)] of long-term treatment in 1,120 patients are discussed. Adverse events during this long-term treatment were also c
Publikováno v:
Neuro-Ophthalmology. 13:5-12
On separate test days, seven healthy test subjects were given a single oral dose each of moclobemide (150 mg), desipramine (50 mg), amitriptyline (50 mg) or placebo in randomized order and under double-blind conditions. Horizontal 30° saccades were
Publikováno v:
International Clinical Psychopharmacology. 7:123-132
Moclobemide, a specific reversible inhibitor of monoamine oxidase that shows a preference for the A isoenzyme, has been developed as a new antidepressive agent. Unlike earlier generation monoamine oxidase inhibitors, moclobemide is devoid of any clin
Publikováno v:
Psychopharmacology. 106:S24-S31
Interactions may occur on pharmacological or pharmacokinetic grounds. Both types of interactions are discussed in relationship with the pharmacological and pharmacokinetic data of moclobemide, a reversible MAO-inhibitor. A variety of interaction stud
Publikováno v:
Acta psychiatrica Scandinavica. 92(4)
The efficacy and the safety of moclobemide (400-600 mg/day), a reversible and selective inhibitor of monoamine oxidase-A (RIMA) and of clomipramine (100-150 mg/day) were compared respectively in 98 and 93 nonmelancholic, nonpsychotic out-patients wit
Publikováno v:
Acta psychiatrica Scandinavica. Supplementum. 386
Noradrenaline (NA) and serotonin, monoamines that increase neurotransmission at the monoaminergic synapses, remain primary targets for antidepressant drugs. To help elucidate NA's role in the action of antidepressants, a model was set up allowing for
Publikováno v:
Canadian journal of psychiatry. Revue canadienne de psychiatrie. 37
Moclobemide--a new, safer antidepressant drug--is described and clinical studies are reviewed. Moclobemide represents a new class of drug, the so-called RIMA compounds--reversible inhibitors of MAO-A. Unlike classical monoamine oxidase (MAO) inhibito
Publikováno v:
Acta Psychiatrica Scandinavica. 82:57-58
Moclobemide was compared with imipramine and placebo in the treatment of major depressive episodes in 75 outpatients. The dosage of moclobemide (25 patients) was 300 mg daily for the first 5 days, after which it could be increased to 600 mg. Imiprami
Autor:
M. Versiani, U. Oggero, P. Alterwain, R. Capponi, F. Dajas, G. Heinze-Martin, C.A. Marquez, M.A. Poleo, L.E. Rivero-Almanzor, L. Rossel, W. Schmid-Burgk, R. Ucha-Udabe
Publikováno v:
British Journal of Psychiatry. 155:72-77
Patients (n = 490) suffering from a major depressive episode according to DSM-III criteria were randomly allocated to groups receiving either moclobemide, imipramine, or placebo treatment. Subjects were treated as out-patients for 6 weeks. On overall