Zobrazeno 1 - 10
of 17
pro vyhledávání: '"W. Schellhase"'
Autor:
Andrew D. Haddow, Farooq Nasar, Christopher W. Schellhase, Roger D. Moon, Susana L. Padilla, Xiankun Zeng, Suzanne E. Wollen-Roberts, Joshua D. Shamblin, Elizabeth C. Grimes, Justine M. Zelko, Kenneth J. Linthicum, Sina Bavari, M. Louise Pitt, John C. Trefry
Publikováno v:
Parasites & Vectors, Vol 10, Iss 1, Pp 1-5 (2017)
Abstract Background Ebola virus (EBOV) infection results in high morbidity and mortality and is primarily transmitted in communities by contact with infectious bodily fluids. While clinical and experimental evidence indicates that EBOV is transmitted
Externí odkaz:
https://doaj.org/article/ce2171e50fc24a3fb60038a2a65d399a
Autor:
Darci R Smith, Charles J Shoemaker, Xiankun Zeng, Aura R Garrison, Joseph W Golden, Christopher W Schellhase, William Pratt, Franco Rossi, Collin J Fitzpatrick, Joshua Shamblin, Adrienne Kimmel, Justine Zelko, Olivier Flusin, Jeffrey W Koehler, Jun Liu, Kayla M Coffin, Keersten M Ricks, Matt A Voorhees, Randal J Schoepp, Connie S Schmaljohn
Publikováno v:
PLoS Pathogens, Vol 15, Iss 9, p e1008050 (2019)
Crimean-Congo hemorrhagic fever (CCHF) is the most medically important tick-borne viral disease of humans and tuberculosis is the leading cause of death worldwide by a bacterial pathogen. These two diseases overlap geographically, however, concurrent
Externí odkaz:
https://doaj.org/article/fb232a195ae94b769f8b4d507e5de74e
Autor:
Sylvia R Trevino, Christopher P Klimko, Matthew C Reed, Michael J Aponte-Cuadrado, Melissa Hunter, Jennifer L Shoe, Joshua R Meyer, Jennifer L Dankmeyer, Sergei S Biryukov, Avery V Quirk, Kristen A Fritts, Steven J Kern, David P Fetterer, Lara J Kohler, Ronald G Toothman, Joel A Bozue, Christopher W Schellhase, Norman Kreiselmeier, Sharon P Daye, Susan L Welkos, Carl Soffler, Patricia L Worsham, David M Waag, Kei Amemiya, Christopher K Cote
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0208277 (2018)
Mouse models have been essential to generate supporting data for the research of infectious diseases. Burkholderia pseudomallei, the etiological agent of melioidosis, has been studied using mouse models to investigate pathogenesis and efficacy of nov
Externí odkaz:
https://doaj.org/article/60b41a1b8810469696fef761663e8da3
Autor:
Jun Liu, John C. Trefry, April M. Babka, Christopher W. Schellhase, Kayla M. Coffin, Janice A. Williams, Jo Lynne W. Raymond, Paul R. Facemire, Taylor B. Chance, Neil M. Davis, Jennifer L. Scruggs, Franco D. Rossi, Andrew D. Haddow, Justine M. Zelko, Sandra L. Bixler, Ian Crozier, Patrick L. Iversen, Margaret L. Pitt, Jens H. Kuhn, Gustavo Palacios, Xiankun Zeng
Publikováno v:
Science translational medicine. 14(631)
Effective therapeutics have been developed against acute Ebola virus disease (EVD) in both humans and experimentally infected nonhuman primates. However, the risk of viral persistence and associated disease recrudescence in survivors receiving these
Autor:
Christopher P. Klimko, Chris W Schellhase, Nancy A. Twenhafel, Jeremy A. Miller, Christopher K. Cote, Donald J. Chabot, John R. Barr, Susham S. Ingavale, Mary E. Wright, Nicholas J. Vietri, Adrian R. Woolfitt, David P Fetterer, Anne E. Boyer, Brandon Somerville, Arthur M. Friedlander, Steven A. Tobery
Publikováno v:
J Infect Dis
Background Inhalational anthrax is rare and clinical experience limited. Expert guidelines recommend treatment with combination antibiotics including protein synthesis-inhibitors to decrease toxin production and increase survival, although evidence i
Autor:
Ronald B. Reisler, Xiankun Zeng, Christopher W. Schellhase, Jeremy J. Bearss, Travis K. Warren, John C. Trefry, George W. Christopher, Mark G. Kortepeter, Sina Bavari, Anthony P. Cardile
Publikováno v:
Viruses, Vol 10, Iss 10, p 513 (2018)
In the 2014–2016 West Africa Ebola Virus (EBOV) outbreak, there was a significant concern raised about the potential for secondary bacterial infection originating from the gastrointestinal tract, which led to the empiric treatment of many patients
Externí odkaz:
https://doaj.org/article/8a9de13dfeff4087a84871d817d8ebac
Autor:
James J Sola, Perry D Wiseman, Joseph Henry, Jay Wells, Joshua L. Moore, Christopher W. Schellhase, Xiankun Zeng, Jeremy J Bearss, Kelly S. Stuthman, Luis A. Lugo-Roman, Jennifer Kalapaca, Darrel Wetzel, Elliot Ramos-Rivera, Annie Madar, William D. Pratt, Veronica Soloveva, Ginger Donnelly, Lydia G Downey, Tami Unangst, Nicole L. Garza, Adele Miller, Jesse T. Steffens, Janice A. Williams, Anthony P. Cardile, Mark G. Kortepeter, Paul W Blair, Isaac L Downs, Mark A. Chappell, Ronald B. Reisler, Franco Rossi, Shannon T Marko, Christian Hofer, Jimmy O. Fiallos, Sean A. Vantongeren, Eugene Blue, Cristian Madar, Karen A. Martins, Sina Bavari
Publikováno v:
J Infect Dis
BackgroundEbola virus disease (EVD) supportive care strategies are largely guided by retrospective observational research. This study investigated the effect of EVD supportive care algorithms on duration of survival in a controlled nonhuman primate (
Autor:
Sara C. McGrath, David M. Kulis, Aysegul Nalca, Jonathan R. Deeds, Virginia Livingston, Donald M. Anderson, David W. Dyer, Jo-lynne W. Raymond, Patricia Ruiz-Olvera, Ondraya M Frick, Mark A. Poli, Sara Ruiz, Christopher W. Schellhase
Publikováno v:
Toxicon. 150:235-250
Preparations of palytoxin (PLTX, derived from Japanese Palythoa tuberculosa) and the congeners 42-OH-PLTX (from Hawaiian P. toxica) and ovatoxin-a (isolated from a Japanese strain of Ostreopsis ovata), as well as a 50:50 mixture of PLTX and 42-OH-PLT
Autor:
Lynn J. Miller, Andrew D. Haddow, Maria Theresa Alera, Christopher W. Schellhase, Richard G. Jarman, Sina Bavari, Suzanne E. Wollen-Roberts, Luis A. Lugo-Roman, Joshua D. Shamblin, M. Louise M. Pitt, Adrienne E. Kimmel, Sarah L. Norris, In-Kyu Yoon, Thomas R. Sprague, Stephanie M. Valdez, Farooq Nasar
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 98:864-867
To evaluate potential immunocompetent small animal models of Zika virus (ZIKV) infection, we inoculated Syrian golden hamsters (subcutaneously or intraperitoneally) and strain 13 guinea pigs (intraperitoneally) with Senegalese ZIKV strain ArD 41525 o
Autor:
Joshua D. Shamblin, Kayla M. Coffin, Darci R. Smith, Matt A. Voorhees, Jeffrey W. Koehler, Xiankun Zeng, Jun Liu, Franco Rossi, Connie S. Schmaljohn, Christopher W. Schellhase, Adrienne E. Kimmel, Charles J. Shoemaker, Justine M. Zelko, Keersten M. Ricks, William D. Pratt, Collin Fitzpatrick, Aura R. Garrison, Randal J. Schoepp, Joseph W. Golden, Olivier Flusin
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 15, Iss 9, p e1008050 (2019)
PLoS Pathogens, Vol 15, Iss 9, p e1008050 (2019)
Crimean-Congo hemorrhagic fever (CCHF) is the most medically important tick-borne viral disease of humans and tuberculosis is the leading cause of death worldwide by a bacterial pathogen. These two diseases overlap geographically, however, concurrent