Zobrazeno 1 - 10 of 71 pro vyhledávání: '"W. S. Sly"'
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Membrane-bound carbonic anhydrase IV is expressed in the luminal plasma membrane of the human gallbladder epithelium
Autor: W S Sly, Anna-Kaisa Parkkila, Sakari Kellokumpu, Kari Kaunisto, Seppo Parkkila, Juha Saarnio, Tatu Juvonen, A Waheed, Hannu Rajaniemi
Publikováno v: Hepatology. 24:1104-1108
Alkaline hepatic bile is acidified in the gallbladder to prevent calcium precipitation and gallstone formation. Because membrane-bound carbonic anhydrase (CA) isoenzyme IV participates with cytoplasmic CA II in the acidification of urine in the kidne
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4b3b5195c6af97a1bfbe65f365e42c
https://doi.org/10.1002/hep.510240521
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3
Depletion of intercalated cells from collecting ducts of carbonic anhydrase II-deficient (CAR2 null) mice
Autor: Seth L. Alper, J. E. Barker, Stephen L. Gluck, Dennis Brown, Sylvie Breton, W. S. Sly
Publikováno v: American Journal of Physiology-Renal Physiology. 269:F761-F774
The kidneys of mice (CAR2-null mice) that are genetically devoid of carbonic anhydrase type II (CAII) were screened by immunocytochemistry with antibodies that distinguish intercalated and principal cells. Immunofluorescent localization of the anion
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b71c21971f281bb7f1439f550df70b
https://doi.org/10.1152/ajprenal.1995.269.6.f761
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4
Increased life span and correction of metabolic defects in murine mucopolysaccharidosis type VII after syngeneic bone marrow transplantation
Autor: E H, Birkenmeier, J E, Barker, C A, Vogler, J W, Kyle, W S, Sly, B, Gwynn, B, Levy, C, Pegors
Publikováno v: Blood. 78:3081-3092
The gusmps/gusmps mouse has no beta-glucuronidase activity and develops murine mucopolysaccharidosis type VII (MPS VII). The clinical and pathologic abnormalities are similar to those found in humans with severe MPS VII. Mutant mice are dysmorphic, d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a705b6d2fe134ca1203f1c1d8c85cf
https://doi.org/10.1182/blood.v78.11.3081.bloodjournal78113081
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5
Distinctive regulation of the functional linkage between the human cation-independent mannose 6-phosphate receptor and GTP-binding proteins by insulin-like growth factor II and mannose 6-phosphate
Autor: Yoshitake Murayama, Tetsuji Okamoto, W S Sly, Toshiaki Katada, Etsuro Ogata, J H Grubb, Ikuo Nishimoto, M Ui, T. Iiri, Tomoichiro Asano
Publikováno v: Journal of Biological Chemistry. 265:17456-17462
The rat insulin-like growth factor II (IGF-II) receptor develops transmembrane signaling functions by directly coupling to a guanine nucleotide-binding protein (G protein) having a 40-kDa alpha subunit, Gi-2, whereas recent studies have indicated tha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec765746ebd68f16a3ed9ee39e51d83
https://doi.org/10.1016/s0021-9258(18)38185-7
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6
A Phenocopy of Caii Deficiency: A Novel Genetic Explanation for Inherited Infantile Osteopetrosis with Distal Renal Tubular Acidosis
Autor: Katherine J. Borthwick, Uwe Kornak, Fiona E. Karet, Seza Ozen, Aysin Bakkaloglu, N Yordam, N Kandemir, G N Shah, Rezan Topaloglu, H Mocan, W S Sly
The rare bone thickening disease osteopetrosis occurs in various forms, one of which is accompanied by renal tubular acidosis (RTA), and is known as Guibaud-Vainsel syndrome or marble brain disease. Clinical manifestations of this autosomal recessive
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff1ebf1dc8d0b0fee24f75355b1e3788
http://hdl.handle.net/11655/14234
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7
Differential expression of cytoplasmic carbonic anhydrases, CA I and II, and membrane-associated isozymes, CA IX and XII, in normal mucosa of large intestine and in colorectal tumors
Autor: A J, Kivela, J, Saarnio, T J, Karttunen, J, Kivelä, A K, Parkkila, S, Pastorekova, J, Pastorek, A, Waheed, W S, Sly, T S, Parkkila, H, Rajaniemi
Publikováno v: Digestive diseases and sciences. 46(10)
This study compares the localization of carbonic anhydrase isozymes (CA) I and II and that of IX and XII in normal large intestine and in colorectal tumors. Immunohistochemical studies were performed on 69 colorectal lesions. While the normal mucosa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c83f7de4ccb4b369993418fbd2a79e7c
https://pubmed.ncbi.nlm.nih.gov/11680594
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9
Regional expression and androgen regulation of carbonic anhydrase IV and II in the adult rat epididymis
Autor: K, Kaunisto, R E, Fleming, J, Kneer, W S, Sly, H, Rajaniemi
Publikováno v: Biology of reproduction. 61(6)
Carbonic anhydrase (CA) is implicated in the acidification of epididymal fluid and thereby in the regulation of sperm maturation and motility. Among the CA isoenzymes, CA IV and II have been shown to be present in the rat epididymal duct epithelium.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eebe5ac356369460d89bebccee864ecf
https://pubmed.ncbi.nlm.nih.gov/10569998
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10
Active site residues of human beta-glucuronidase. Evidence for Glu(540) as the nucleophile and Glu(451) as the acid-base residue
Autor: M R, Islam, S, Tomatsu, G N, Shah, J H, Grubb, S, Jain, W S, Sly
Publikováno v: The Journal of biological chemistry. 274(33)
Human beta-glucuronidase (hGUSB) is a member of family 2 glycosylhydrolases that cleaves beta-D-glucuronic acid residues from the nonreducing termini of glycosaminoglycans. Amino acid sequence and structural homology of hGUSB and Escherichia coli bet
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7ce1c0fb80560a56ff6a1cf3f6a1a94b
https://pubmed.ncbi.nlm.nih.gov/10438523
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