Zobrazeno 1 - 10
of 54
pro vyhledávání: '"W. S. Davidson"'
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 7, Pp 1519-1528 (1996)
Human apolipoprotein A-I (apoA-I) is the major protein component of high density lipoproteins (HDL) where it defines the particle structure and stability and functions as the main activator of the enzyme lecithin:cholesterol acyltransferase (LCAT). A
Externí odkaz:
https://doaj.org/article/c4d0b94ea834403383d54f995c5ba15e
Autor:
John T. Melchior, Hannah Sexmith, Deborah A. Elder, Theodoros Kelesidis, Anna Heink, Thomas H. Inge, David Y. Hui, Amy S. Shah, W S Davidson
Publikováno v:
International journal of obesity (2005), vol 41, iss 1
International journal of obesity (2005)
International journal of obesity (2005)
Background/objectiveYouth with obesity have an altered high-density lipoprotein (HDL) subspecies profile characterized by depletion of large apoE-rich HDL particles and an enrichment of small HDL particles. The goal of this study was to test the hypo
Autor:
Andrew B. Herr, Scott E. Street, Jere P. Segrest, Jamie Morris, Loren E Smith, Thomas B. Thompson, W S Davidson, Allison L Cooke, Jay W. Heinecke, John T. Melchior, Amy S. Shah, W G Jerome
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
The structure of apolipoprotein (APOA1), the major protein of high density lipoproteins (HDL), can modulate protein interactions affecting the cardioprotective functions of HDL particles. APOA1 on nascent discoidal HDL is composed of ten, tandem, α-
Autor:
John T. Melchior, Jere P. Segrest, Jamie Morris, W S Davidson, Martin K. Jones, Ryan G. Walker, Thomas B. Thompson
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
Apolipoprotein (apo)A-I, the major protein constituent of high density lipoproteins (HDL), acts as a conformationally dynamic scaffold on the surface of the particle. Evidence suggests apoA-I conformation dictates HDL functionality and capacity to in
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
High-density lipoproteins (HDL) play a critical role in lipid transport and vascular lipid homeostasis. HDL is heterogeneous, with particles varying in size, composition, and functionality. Proteomic studies have shown that HDL can host as many as 94
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
Severe obesity is a major problem among US adolescents and traditional weight loss strategies, including lifestyle intervention, have had limited efficacy. Bariatric surgery has grown in popularity because it results in rapid weight loss while improv
Publikováno v:
Current Atherosclerosis Reports. 18
Plasma high-density lipoprotein cholesterol (HDL-C) concentration is a negative risk factor for atherosclerotic cardiovascular disease (CVD). Despite this, most attempts to raise plasma HDL-C concentrations in a cardioprotective way have failed. Rece
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
Recent failures of high density lipoprotein cholesterol (HDL-C) raising therapies have shifted attention on understanding HDL functionality vs. quantity. For example, the ability of HDL to promote cholesterol efflux has been recently shown to be high
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
X-ray crystallography studies of lipid-free apolipoprotein A-I (apoA-I) and related apoA-IV have shown that the proteins form a reciprocating dimer which could be directly related to the structural organization of lipid-bound apoA-I. Previous work ha
Autor:
W S Davidson, J Brattey
Publikováno v:
Canadian Journal of Fisheries and Aquatic Sciences. 53:333-341
Pour l'etude de la variation genetique du complexe des genes d'ARN ribosomaux (rDNA) de 181 specimens de Pseudoterranova decipiens provenant de trois especes de phoques et de six especes de poissons marins recueillis sur une vaste etendue du Canada a