Zobrazeno 1 - 10
of 23
pro vyhledávání: '"W. S. Barclay"'
Autor:
D. A. Leach, A. Mohr, E. S. Giotis, E. Cil, A. M. Isac, L. L. Yates, W. S. Barclay, R. M. Zwacka, C. L. Bevan, G. N. Brooke
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
TMPRSS2 is regulated by androgen receptor signalling in the prostate, however it is unclear if blocking this signalling is beneficial in the context of SARS-CoV-2 lung infection. Here the authors show that antiandrogen treatment downregulates TMPRSS2
Externí odkaz:
https://doaj.org/article/054d5eddfbac4f51bb25f10d584c7186
Autor:
P F McKay, J Zhou, R Frise, A K Blakney, C R Bouton, Z Wang, K Hu, K Samnuan, J C Brown, R Kugathasan, J Yeow, M M Stevens, W S Barclay, J S Tregoning, R J Shattock
COVID-19 has demonstrated the power of RNA vaccines as part of a pandemic response toolkit. Another virus with pandemic potential is influenza. Further development of RNA vaccines in advance of a future influenza pandemic will save time and lives. As
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff43ca277baeba758f11f2266d54b0f1
http://hdl.handle.net/10044/1/99986
http://hdl.handle.net/10044/1/99986
There is increasing interest in the development of new, ‘universal’ influenza vaccines (UIV) that––unlike current vaccines––are effective against a broad range of seasonal influenza strains, as well as against novel pandemic viruses. Whil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4edba318b1b3b1a7ef43e94538070c02
Publikováno v:
Scopus-Elsevier
In this report we describe the rescue of a transfectant influenza A virus which stably expresses a heterologous protein, bacterial chloramphenicol acetyltransferase (CAT). The foreign sequences encoding CAT are expressed as part of an essential influ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9191ecf647bb6a2e80153116b41dc00
https://doi.org/10.1128/jvi.68.7.4486-4492.1994
https://doi.org/10.1128/jvi.68.7.4486-4492.1994
Autor:
W S, Barclay
Publikováno v:
Canadian Medical Association journal. 45(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e089421774e44e3b62d90c4edf48afe2
https://pubmed.ncbi.nlm.nih.gov/20322293
https://pubmed.ncbi.nlm.nih.gov/20322293
Publikováno v:
Journal of Medical Virology. 36:251-258
Mouse monoclonal antibodies (MAbs) against three distinct antigenic sites on rhinovirus type 2 have been obtained and the sites identified. We describe how these MAbs were used in a blocking test to detect antibodies in human sera directed against th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc45bab462be2ec3876c636468235137
https://doi.org/10.1002/jmv.1890360404
https://doi.org/10.1002/jmv.1890360404
Publikováno v:
Journal of Medical Virology
Rhinovirus‐specific antibodies have traditionally been detected by their ability to neutralise the homologous rhinovirus serotype in tissue culture. Recently, however, we have described an enzyme‐linked immunosorbent assay that detects rhinovirus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16916cebb2f58b1f4c17130a1c10e54
https://doi.org/10.1002/jmv.1890250411
https://doi.org/10.1002/jmv.1890250411
Publikováno v:
Epidemiology and Infection. 103:659-669
SUMMARYThe specific humoral immune response of 17 volunteers to infection with human rhinovirus type 2 (HRV-2) has been measured both by neutralization and by ELISA. Six volunteers who had HRV-2-specific antibodies in either serum or nasal secretions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f2287146bbeec597fc31dc13ee9822
https://doi.org/10.1017/s095026880003106x
https://doi.org/10.1017/s095026880003106x
Autor:
N, SCHMITT, W S, BARCLAY
Publikováno v:
Canadian journal of public health = Revue canadienne de sante publique. 53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0caaededcff02976f89d28270eec3dde
https://pubmed.ncbi.nlm.nih.gov/13992080
https://pubmed.ncbi.nlm.nih.gov/13992080