Zobrazeno 1 - 10
of 32
pro vyhledávání: '"W. Rod Hardy"'
Autor:
Kevin Yau, Alexandra Kurtesi, Freda Qi, Melanie Delgado-Brand, Tulunay R. Tursun, Queenie Hu, Miten Dhruve, Christopher Kandel, Omosomi Enilama, Adeera Levin, Yidi Jiang, W. Rod Hardy, Darren A. Yuen, Jeffrey Perl, Christopher T. Chan, Jerome A. Leis, Matthew J. Oliver, Karen Colwill, Anne-Claude Gingras, Michelle A. Hladunewich
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract Neutralization of Omicron subvariants by different bivalent vaccines has not been well evaluated. This study characterizes neutralization against Omicron subvariants in 98 individuals on dialysis or with a kidney transplant receiving the BNT
Externí odkaz:
https://doaj.org/article/65e517f6293b477ba717d5a35a58d87f
Autor:
Victor H. Ferreira, Javier T. Solera, Queenie Hu, Victoria G. Hall, Berta G. Arbol, W. Rod Hardy, Reuben Samson, Tina Marinelli, Matthew Ierullo, Avneet Kaur Virk, Alexandra Kurtesi, Faranak Mavandadnejad, Beata Majchrzak-Kita, Vathany Kulasingam, Anne-Claude Gingras, Deepali Kumar, Atul Humar
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Immunocompromised individuals are predisposed to severe SARS-CoV-2 infection, with transplant recipients typically displaying impaired immune response to pathogens, due to typical life-long immunosuppressive treatment. In this work, the authors evalu
Externí odkaz:
https://doaj.org/article/9fad6f00c4f145a2b068a68d5f6b0a55
Autor:
Roya M. Dayam, Jaclyn C. Law, Rogier L. Goetgebuer, Gary Y.C. Chao, Kento T. Abe, Mitchell Sutton, Naomi Finkelstein, Joanne M. Stempak, Daniel Pereira, David Croitoru, Lily Acheampong, Saima Rizwan, Klaudia Rymaszewski, Raquel Milgrom, Darshini Ganatra, Nathalia V. Batista, Melanie Girard, Irene Lau, Ryan Law, Michelle W. Cheung, Bhavisha Rathod, Julia Kitaygorodsky, Reuben Samson, Queenie Hu, W. Rod Hardy, Nigil Haroon, Robert D. Inman, Vincent Piguet, Vinod Chandran, Mark S. Silverberg, Anne-Claude Gingras, Tania H. Watts
Publikováno v:
JCI Insight, Vol 7, Iss 11 (2022)
BACKGROUND Limited information is available on the impact of immunosuppressants on COVID-19 vaccination in patients with immune-mediated inflammatory diseases (IMID).METHODS This observational cohort study examined the immunogenicity of SARS-CoV-2 mR
Externí odkaz:
https://doaj.org/article/5efd773f1af64049a8135d42e2a56cd2
Autor:
Ly-Sha Ee, Kurtis N. McCannell, Yang Tang, Nancy Fernandes, W. Rod Hardy, Michael R. Green, Feixia Chu, Thomas G. Fazzio
Publikováno v:
Stem Cell Reports, Vol 8, Iss 6, Pp 1488-1496 (2017)
The Nucleosome Remodeling and Deacetylase (NuRD) complex is a chromatin regulatory complex that functions as a transcriptional co-repressor in metazoans. The NuRD subunit MBD3 is essential for targeting and assembly of a functional NuRD complex as we
Externí odkaz:
https://doaj.org/article/f8e6ef562d6546779d980cf547c22c37
Autor:
Javier T Solera, Berta G Arbol, Victor H Ferreira, Alexandra Kurtesi, Queenie Hu, Matthew Ierullo, Adriana Valverde-Zuniga, Ismail Raslan, Asma Nasir, Clara Grizales, W Rod Hardy, Vathany Kulasingam, Anne-Claude Gingras, Atul Humar, Deepali Kumar
Publikováno v:
The Lancet Infectious Diseases. 23:528-530
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4feeefbc3b0b4c9f3cd2b21a3329c46f
https://doi.org/10.1016/s1473-3099(23)00208-6
https://doi.org/10.1016/s1473-3099(23)00208-6
Autor:
Victor H Ferreira, Matthew Ierullo, Faranak Mavandadnejad, Alexandra Kurtesi, Queenie Hu, W Rod Hardy, Victoria G Hall, Natalia Pinzon, Demitra Yotis, Anne-Claude Gingras, Sara Belga, Sarah Shalhoub, Marie-Josée Hébert, Atul Humar, Dima Kabbani, Deepali Kumar
Publikováno v:
Clinical Infectious Diseases.
Background In solid organ transplant (SOT) recipients, the primary vaccination series against Coronavirus Disease 2019 is 3 doses followed by boosters. We determined whether a fourth dose booster induced Omicron BA.4/5 neutralizing antibodies (nAbs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::279780bfbb9b7488c60b31f5e1bd18b2
https://doi.org/10.1093/cid/ciad175
https://doi.org/10.1093/cid/ciad175
Autor:
Jun Liu, Patrick Budylowski, Reuben Samson, Bryan D. Griffin, Giorgi Babuadze, Bhavisha Rathod, Karen Colwill, Jumai A. Abioye, Jordan A. Schwartz, Ryan Law, Lily Yip, Sang Kyun Ahn, Serena Chau, Maedeh Naghibosadat, Yuko Arita, Queenie Hu, Feng Yun Yue, Arinjay Banerjee, W. Rod Hardy, Karen Mossman, Samira Mubareka, Robert A. Kozak, Michael S. Pollanen, Natalia Martin Orozco, Anne-Claude Gingras, Eric G. Marcusson, Mario A. Ostrowski
Publikováno v:
Science Advances
Safe and effective vaccines are needed to end the COVID-19 pandemic. Here, we report the preclinical development of a lipid nanoparticle–formulated SARS-CoV-2 mRNA vaccine, PTX-COVID19-B. PTX-COVID19-B was chosen among three candidates after the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a071769597d786d16b3c6fb23989fb9d
http://europepmc.org/articles/PMC8769538
http://europepmc.org/articles/PMC8769538
Autor:
Heidi Wood, Bhavisha Rathod, Kathy Manguiat, Nazrana Haq, Yves Durocher, Mohammad Mozafarihashjin, Shiva Barati, Alyssia Robinson, Mario A. Ostrowski, Gary Chao, Julia Garnham Takaoka, Allison McGeer, Anne-Claude Gingras, Mariam Iskilova, Kento T. Abe, Sharon E. Straus, Jennifer L. Gommerman, Salma Sheikh-Mohamed, Queenie Hu, Reuben Samson, Karen Green, Lois Gilbert, W. Rod Hardy, Aimee Paterson, Adrian Pasculescu, Yuko Arita, Alyson Takaoka, Eric G. Marcusson, Jenny Wang, Keelia Quinn De Launay, Karen Colwill, Angel Li, Christine Fahim, Mahya Fazel-Zarandi
Prioritizing Ontario’s long-term care home (LTCH) residents for vaccination against severe acute respiratory syndrome coronavirus 2 has drastically reduced their disease burden; however, recent LTCH outbreaks of variants of concern (VOCs) have rais
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ea8d80fc53d6717bdc7e9bdd962ab94
https://doi.org/10.1101/2021.08.06.21261721
https://doi.org/10.1101/2021.08.06.21261721
Autor:
Thomas G. Fazzio, Ly-Sha Ee, Michael R. Green, Yang Tang, W. Rod Hardy, Kurtis N. McCannell, Nancy Fernandes, Feixia Chu
Publikováno v:
Stem Cell Reports, Vol 8, Iss 6, Pp 1488-1496 (2017)
Stem Cell Reports
Stem Cell Reports
Summary The Nucleosome Remodeling and Deacetylase (NuRD) complex is a chromatin regulatory complex that functions as a transcriptional co-repressor in metazoans. The NuRD subunit MBD3 is essential for targeting and assembly of a functional NuRD compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b74a1b09b0e6813d1cdeb3167e73a635
http://www.sciencedirect.com/science/article/pii/S2213671117301741
http://www.sciencedirect.com/science/article/pii/S2213671117301741
Autor:
Manali Tilak, Kelly A. Petersen, Lamine Aoudjit, Susan E. Quaggin, Tomoko Takano, W. Rod Hardy, Claire E. Martin, Vera Eremina, Nina Jones
Publikováno v:
Journal of the American Society of Nephrology : JASN. 29(1)
Nephrin is a key structural component of the podocyte slit diaphragm, and proper expression of nephrin on the cell surface is critical to ensure integrity of the blood filtration barrier. Maintenance of nephrin within this unique cell junction has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec5eae7f01a6a887929817f3be3256f
https://pubmed.ncbi.nlm.nih.gov/29081509
https://pubmed.ncbi.nlm.nih.gov/29081509