Zobrazeno 1 - 10
of 120
pro vyhledávání: '"W. Robb Maclellan"'
Autor:
Zhenhe Zhang, Miles Freeman, Yiqiang Zhang, Danny El-Nachef, George Davenport, Allison Williams, W. Robb MacLellan
Publikováno v:
PLoS ONE, Vol 18, Iss 2 (2023)
Aims Accumulating data demonstrates that new adult cardiomyocytes (CMs) are generated throughout life from pre-existing CMs, although the absolute magnitude of CM self-renewal is very low. Modifying epigenetic histone modifications or activating the
Externí odkaz:
https://doaj.org/article/79e6931d5cd24cc1ab391abf78241d5c
Autor:
Kyohei Oyama, Danny El-Nachef, Chen Fang, Hidemi Kajimoto, Jeremy P. Brown, Prim B. Singh, W. Robb MacLellan
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-15 (2018)
Abstract Background Heterochromatin, which is formed when tri-methyl lysine 9 of histone H3 (H3K9me3) is bound by heterochromatin 1 proteins (HP1s), plays an important role in differentiation and senescence by silencing cell cycle genes. Cardiac myoc
Externí odkaz:
https://doaj.org/article/a8976ee3773e4a23bd563d67ccc34511
Autor:
Nuria Gago-Lopez, Obinna Awaji, Yiqiang Zhang, Christopher Ko, Ali Nsair, David Liem, April Stempien-Otero, W. Robb MacLellan
Publikováno v:
Stem Cell Reports, Vol 2, Iss 5, Pp 576-591 (2014)
Despite over a decade of intense research, the identity and differentiation potential of human adult cardiac progenitor cells (aCPC) remains controversial. Cardiospheres have been proposed as a means to expand aCPCs in vitro, but the identity of the
Externí odkaz:
https://doaj.org/article/aae6e32dceb943dfa92b02190fa70261
Autor:
Ali Nsair, Katja Schenke-Layland, Ben Van Handel, Denis Evseenko, Michael Kahn, Peng Zhao, Joseph Mendelis, Sanaz Heydarkhan, Obina Awaji, Miriam Vottler, Susanne Geist, Jennifer Chyu, Nuria Gago-Lopez, Gay M. Crooks, Kathrin Plath, Josh Goldhaber, Hanna K. A. Mikkola, W. Robb MacLellan
Publikováno v:
PLoS ONE, Vol 7, Iss 10 (2012)
Externí odkaz:
https://doaj.org/article/c05b004ab3a14673b08f5b5e2ad98fcf
Autor:
Nabil Dib M.D., Patrick Mccarthy, Ann Campbell, Michael Yeager, Francis D. Pagani, Susan Wright, W. Robb Maclellan, Gregg Fonarow, Howard J. Eisen, Robert E. Michler, Philip Binkley, Diane Buchele, Ronald Korn, Marwan Ghazoul, Jonathan Dinsmore, Shaun R. Opie, Edward Diethrich
Publikováno v:
Cell Transplantation, Vol 14 (2005)
Successful autologous skeletal myoblast transplantation into infarcted myocardium in a variety of animal models has demonstrated improvement in cardiac function. We evaluated the safety and feasibility of transplanting autologous myoblasts into infar
Externí odkaz:
https://doaj.org/article/c74f1bd2d6ee4bc885238703af46e7a4
Autor:
Silvia Marchiano, Kenta Nakamura, Hans Reinecke, Lauren Neidig, Jordan Klaiman, Xiulan Yang, Leslie Blakely, Faith Kalucki, Sarah Dupras, Bjorn C. Knollmann, Steven Kattman, Nathan Sniadecki, Scott Thies, W. Robb MacLellan, Alessandro Bertero, Charles Murry
Publikováno v:
Heart Rhythm. 20:S270
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d3e6681737a93a21889b0554f4d8c1b
https://doi.org/10.1016/j.hrthm.2023.03.730
https://doi.org/10.1016/j.hrthm.2023.03.730
Publikováno v:
International journal of cardiology and cardiovascular diseases. 1(1)
Histological analysis of fluorescently labeled tissues has been a critical tool to understand molecular organization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d91cb4ac6334688e4929c75c1f80276
https://pubmed.ncbi.nlm.nih.gov/35243481
https://pubmed.ncbi.nlm.nih.gov/35243481
Autor:
Alessandro Bertero, Rong Tian, Kevin C. Cain, R. Scott Thies, Anu Jayabalu, Melissa R. Robinson, W. Robb MacLellan, Danny El-Nachef, Dale Whittington, Daisy S. Nakamura, Faith A. Kalucki, Hiroshi Tsuchida, Lauren E. Neidig, Gerhard J. Weber, Charles E. Murry, Silvia Marchianò, Lil Pabon, Akiko Futakuchi-Tsuchida, Bjorn C. Knollmann, Xiulan Yang, Steven Kattman, Hans Reinecke, Sarah K. Dupras, Kenta Nakamura
Publikováno v:
Stem Cell Reports
Summary Heart failure remains a significant cause of morbidity and mortality following myocardial infarction. Cardiac remuscularization with transplantation of human pluripotent stem cell-derived cardiomyocytes is a promising preclinical therapy to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1189e00de9d9819aacf1d2936c5a883
http://hdl.handle.net/2318/1804571
http://hdl.handle.net/2318/1804571
Autor:
W. Robb MacLellan, Charles E. Murry
Publikováno v:
Science (New York, N.Y.). 367(6480)
After 20 years of research, pluripotent stem cells move to the fore to treat heart disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f84004f60522a60e36cc3864288004
https://pubmed.ncbi.nlm.nih.gov/32079761
https://pubmed.ncbi.nlm.nih.gov/32079761
Autor:
Kenta Nakamura, W. Robb MacLellan
Publikováno v:
Heart Failure: a Companion to Braunwald's Heart Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::162a0c68e1051e979d8c166526dd1bb7
https://doi.org/10.1016/b978-0-323-60987-6.00041-7
https://doi.org/10.1016/b978-0-323-60987-6.00041-7