Zobrazeno 1 - 10
of 183
pro vyhledávání: '"W. Reiss"'
Autor:
Li Chen, Jacqueline Mudd, Michael Ittmann, Carol J. Bult, Amanda R. Kirane, Jelena Randjelovic, Stephen Scott, Yige Wu, Li Ding, Vashisht G. Yennu-Nanda, Jing Wang, Christopher D. Lanier, Maihi Fujita, Emilio Cortes-Sanchez, Sienna Rocha, Susan G. Hilsenbeck, Kian-Huat Lim, Fernanda Martins Rodrigues, Jill Rubinstein, Nicholas Mitsiades, Haiyin Lin, Jayamanna Wickramasinghe, Andrew Butterfield, Bryan E. Welm, Alana L. Welm, Jose P. Zevallos, Jason Held, Nicole B. Coggins, Song Cao, Yuanxin Xi, Brenda C. Timmons, Paul Lott, David Menter, Shunqiang Li, Tina Primeau, Fei Yang, Andrea Wang-Gillam, Ramaswamy Govindan, Dali Li, Brandi Davis-Dusenbery, Sara Seepo, Michael C. Wendl, Jeffrey Grover, Brian S. White, Clifford G. Tepper, Peter N. Robinson, Michael A. Davies, Zhengtao Chu, Michael W. Lloyd, Hua Sun, Xiaoshan Zhang, Tamara Stankovic, Dylan Fingerman, Anuj Srivastava, Luis G. Carvajal-Carmona, Don L. Gibbons, Lijun Yao, Rebecca Aft, Hongyong Zhang, Ismail Meraz, John DiGiovanna, Scott Kopetz, Ling Zhao, Guadalupe Polanco-Echeverry, Feng Chen, Jeremy Hoog, Matthew A. Wyczalkowski, George Xu, John D. Minna, Yi Xu, Julie Belmar, Xiaowei Xu, Luc Girard, Dennis A. Dean, Tijana Borovski, Chong-xian Pan, Cynthia X. Ma, Alexa Morales Arana, Yize Li, Turcin Saridogan, Steven B. Neuhauser, Sandra Scherer, Vicki Chin, Rose Tipton, David R. Gandara, Sherri R. Davies, Argun Akcakanat, Rajesh Patidar, Julie K. Schwarz, Soner Koc, Gao Boning, Michael Kim, Bryce P. Kirby, Yvonne A. Evrard, Hyunsil Park, Christian Frech, Chia-Kuei Mo, Ran Zhang, Brian A. Van Tine, Jonathan W. Reiss, Min Xiao, Xing Yi Woo, Tiffany Le, Ana Estrada, Xiaofeng Zheng, Jeffrey A. Moscow, Mourad Majidi, Nadezhda V. Terekhanova, Katherine Fuh, Erkan Yuca, Timothy A. Yap, Jianhua Zhang, Matthew J. Ellis, Shannon Westin, James H. Doroshow, Vito W. Rebecca, Moon S. Chen, Coya Tapia, Reyka G Jayasinghe, Jack A. Roth, Jithesh Augustine, Ryan C. Fields, Michae T. Tetzlaff, Michael T. Lewis, Kurt W. Evans, Ralph W. deVere White, Brian J. Sanderson, May Cho, Jeffrey H. Chuang, Tiffany Wallace, Ryan Jeon, Ted Toal, Matthew H. Bailey, Bert W. O'Malley, Katherine L. Nathanson, Qin Liu, Benjamin J. Raphael, Jingqin Luo, Salma Kaochar, Huiqin Chen, Rajasekharan Somasundaram, Daniel Cui Zhou, John F. DiPersio, Andrew V. Kossenkov, Bingliang Fang, Vanessa Jensen, Simone Zaccaria, Alexey Sorokin, Ai-Hong Ma, Sidharth V. Puram, Min Jin Ha, Meenhard Herlyn, R. Jay Mashl, Kelly Gale, Bingbing Dai, Lacey E. Dobrolecki, Chieh-Hsiang Yang, Funda Meric-Bernstam
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Nature Communications
Nature Communications
Development of candidate cancer treatments is a resource-intensive process, with the research community continuing to investigate options beyond static genomic characterization. Toward this goal, we have established the genomic landscapes of 536 pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6a532801486680203051ed293ca8f82
https://doaj.org/article/e6286532f9bc487a87943a142621d7a3
https://doaj.org/article/e6286532f9bc487a87943a142621d7a3
Autor:
Kallanthottathil G. Rajeev, Nicole M. Gaudelli, Yusuf S. Nasrullah, Soumyashree A. Gangopadhyay, Andrew M. Bellinger, Sara P. Garcia, James Madsen, Jamie E. DeNizio, Athul Sanjeev, Lisa N. Kasiewicz, Giuseppe Ciaramella, Aaron Beach, Ellen Rohde, Anne Marie Mazzola, Thomas V. Colace, Kui Wang, Sowmya Iyer, Caroline W. Reiss, Padma Malyala, Steven H. Y. Fan, Victoria Clendaniel, Christopher J. Cheng, Jennifer Lavoie, Taiji Mizoguchi, Yuri Matsumoto, Madeleine Shay, Kiran Musunuru, Leslie E. Stolz, Maurine C. Braun, Chaitali Dutta, Ying K. Tam, Joseph Nneji, Ryan Garrity, Alexandra C. Chadwick, Souvik Biswas, Michael Amaonye, John D. Ganey, Mary R. Stahley, Huilan Ren, Huei-Mei Chen, Kathleen Berth, Sekar Kathiresan
Publikováno v:
Nature. 593:429-434
Gene-editing technologies, which include the CRISPR–Cas nucleases1–3 and CRISPR base editors4,5, have the potential to permanently modify disease-causing genes in patients6. The demonstration of durable editing in target organs of nonhuman primat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202cb5c958a9c7ceda5f4b4bf29aa718
https://doi.org/10.1038/s41586-021-03534-y
https://doi.org/10.1038/s41586-021-03534-y
Autor:
Andreas Karabis, Rajpal Singh, W. Reiss, Joseph Dang, Yilin Jiang, Jennie H. Best, Jennifer Uyei, Yuting Kuang
Publikováno v:
Rheumatology and Therapy
Introduction The objective of this study was to evaluate the relative efficacy of targeted immune modulators (TIMs) in TIM-naïve/mixed populations (≤ 20% TIM-experienced) and TIM-experienced (> 20% TIM-experienced) adults with moderate-to-severe r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7145f37b289d92212da143aebe148b08
http://europepmc.org/articles/PMC8217484
http://europepmc.org/articles/PMC8217484
Autor:
W. Reiss, T. Blachley, Steve Zlotnick, Kelechi Emeanuru, Joel M. Kremer, Dimitrios A Pappas, Jennie H. Best
Publikováno v:
Rheumatology and Therapy
Introduction Understanding the durability of response to treatment and factors associated with failure to maintain response in a real-world setting can inform treatment decisions for patients with rheumatoid arthritis (RA). The aim of this study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9a920118f837a21f35275962b62233
https://doi.org/10.1007/s40744-021-00285-0
https://doi.org/10.1007/s40744-021-00285-0
Autor:
Lavannya Pandit, Julia Garcia-Diaz, Gerard J. Criner, Benjamin Kramer, Jamie Freedman, Maria F. González-Lara, Rachel Baden, Linda Yau, Jian Han, Shalini V. Mohan, Miriam L Cameron, Reena Shah, Carlos Salama, Victoria Chávez, Martha Mekebeb-Reuter, Ferdinando Lima de Menezes, Jeffrey D. Neidhart, Emma Kaplan-Lewis, W. Reiss, Beverly Assman
Publikováno v:
New England Journal of Medicine
The New England Journal of Medicine
The New England Journal of Medicine
Background Coronavirus disease 2019 (Covid-19) pneumonia is often associated with hyperinflammation. Despite the disproportionate incidence of Covid-19 among underserved and racial and ethnic minority populations, the safety and efficacy of the anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945cc410d68f153659cd71656758fd56
https://doi.org/10.1056/nejmoa2030340
https://doi.org/10.1056/nejmoa2030340
Autor:
Jan Tebbe, Florian Richter, Sarah J. Spencer, Karolina A. Kosakowska, Wayne Coco, Christien Bednarski, Cindy Park-Windhol, Abraham Scaria, Michael Biag Gamalinda, Ryo Takeuchi, Scott Munzer, Akiko Noma, Albena Kantardzhieva, Andre Cohnen, Michael Lukason, Mariacarmela Allocca, Caroline W. Reiss, Andrew M. Scharenberg, Brian J. Cafferty, Christian Pitzler, Stefanie Gehrig-Giannini, Kui Wang, Ashish Gupta, Kerstin Dehne, Sane Shailendra, Christina Galonska, Moritz Schmidt, Christopher J. Cheng
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
Streptococcus pyogenes (Spy) Cas9 has potential as a component of gene therapeutics for incurable diseases. One of its limitations is its large size, which impedes its formulation and delivery in therapeutic applications. Smaller Cas9s are an alterna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5691833fda2217e508f7975cce09f1c3
https://doi.org/10.1038/s41467-021-24454-5
https://doi.org/10.1038/s41467-021-24454-5
Autor:
Ferdinando Lima de Menezes, W. Reiss, Emma Kaplan-Lewis, Maria F. González-Lara, Beverly Assman, Miriam L. Cameron, Linda Yau, Reena Shah, Gerard J. Criner, Jian Han, Julia Garcia-Diaz, Jamie Freedman, Martha Mekebeb-Reuter, Benjamin Kramer, Rachel Baden, Shalini V. Mohan, Victoria Chávez, Jeffrey D. Neidhart, Lavannya M. Pandit, Carlos Salama
BackgroundCoronavirus disease 2019 (Covid-19) pneumonia is often associated with hyperinflammation. Safety and efficacy of the anti–interleukin-6 receptor antibody tocilizumab was evaluated in patients hospitalized with Covid-19 pneumonia.MethodsNo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4ade2fe46511f13e8cfbe55a0f84968
https://doi.org/10.1101/2020.10.21.20210203
https://doi.org/10.1101/2020.10.21.20210203
Publikováno v:
Biochemistry
The modularity of protein domains is well-known, but the existence of independent domains that confer function in RNA is less established. Recently, a family of RNA aptamers termed ykkC was discovered; they bind at least four ligands of very differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7564162754f2f52402ea7aee0736edaf
https://pubmed.ncbi.nlm.nih.gov/32202416
https://pubmed.ncbi.nlm.nih.gov/32202416
Publikováno v:
Structure. 25:195-202
The guanidine-I riboswitch is a conserved RNA element with approximately 2,000 known examples across four phyla of bacteria. It exists upstream of nitrogen metabolism and multidrug resistance transporter genes and alters expression through the specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaceb266607e983d3d5da2c7d68fc114
https://doi.org/10.1016/j.str.2016.11.020
https://doi.org/10.1016/j.str.2016.11.020
Autor:
W. Reiss, T. Blachley, Kelechi Emeanuru, Joel M. Kremer, Steve Zlotnick, Jennie H. Best, Dimitrios A. Pappas
Publikováno v:
Annals of the Rheumatic Diseases. 79:305-306
Background:Understanding the durability of response to biologics and factors associated with failure to maintain response in a real-world setting can inform treatment decisions for patients with rheumatoid arthritis (RA).Objectives:To evaluate the du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d4bb25ceb8f6bfd57e6f83942cf09d6
https://doi.org/10.1136/annrheumdis-2020-eular.571
https://doi.org/10.1136/annrheumdis-2020-eular.571