Zobrazeno 1 - 10
of 238
pro vyhledávání: '"W. Rausch"'
Publikováno v:
Viruses, Vol 16, Iss 1, p 108 (2024)
The principal barrier to an HIV-1 cure is the persistence of infected cells harboring replication-competent proviruses despite antiretroviral therapy (ART). HIV-1 transcriptional suppression, referred to as viral latency, is foremost among persistenc
Externí odkaz:
https://doaj.org/article/f40b23e4ed8741b5894d6df536a918af
Publikováno v:
Viruses, Vol 14, Iss 1, p 104 (2022)
COVID-19 vaccines were first administered on 15 December 2020, marking an important transition point for the spread of SARS-CoV-2 in the United States (U.S.). Prior to this point in time, the virus spread to an almost completely immunologically naïv
Externí odkaz:
https://doaj.org/article/11d3d26fa43740f5a3e281f7522b0c9c
Autor:
Andrea O. Y. Luk, Benny C. Y. Zee, Marc Chong, Risa Ozaki, Carl W. Rausch, Michael H. M. Chan, Ronald C. W. Ma, Alice P. S. Kong, Francis C. C. Chow, Juliana C. N. Chan
Publikováno v:
BMC Endocrine Disorders, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Galactomannan(s) are plant-derived fiber shown to reduce post-prandial blood glucose by delaying intestinal absorption of carbohydrates and slowing down gastric emptying. We examined glucose-lowering effects of BTI320, a propriety
Externí odkaz:
https://doaj.org/article/e4ba2a9f64f84aefa07c632fd6644b79
Autor:
Valerie F. Boltz, Cristina Ceriani, Jason W. Rausch, Wei Shao, Michael J. Bale, Brandon F. Keele, Rebecca Hoh, Jeffrey M. Milush, Steve G. Deeks, Frank Maldarelli, Mary F. Kearney, John M. Coffin
Publikováno v:
Viruses, Vol 13, Iss 5, p 799 (2021)
The latent HIV-1 reservoir is comprised of stably integrated and intact proviruses with limited to no viral transcription. It has been proposed that latent infection may be maintained by methylation of pro-viral DNA. Here, for the first time, we inve
Externí odkaz:
https://doaj.org/article/bd8b46cd47d04f51abd3c9fcd6fbe251
Publikováno v:
Frontiers in Microbiology, Vol 8 (2018)
Viral RNAs were selected by evolution to possess maximum functionality in a minimal sequence. Depending on the classification of the virus and the type of RNA in question, viral RNAs must alternately be replicated, spliced, transcribed, transported f
Externí odkaz:
https://doaj.org/article/7e9c1637e24845a4b7d368ed35e655d1
Autor:
Jason W. Rausch, Stuart F. J. Le Grice
Publikováno v:
Viruses, Vol 7, Iss 6, Pp 3053-3075 (2015)
HIV-1 Rev is an ~13 kD accessory protein expressed during the early stage of virus replication. After translation, Rev enters the nucleus and binds the Rev response element (RRE), a ~350 nucleotide, highly structured element embedded in the env gene
Externí odkaz:
https://doaj.org/article/1acdefa5bc7442869daf6dd435aa198a
Autor:
Kevin W. Joseph, Elias K. Halvas, Leah D. Brandt, Sean C. Patro, Jason W. Rausch, Abha Chopra, Simon Mallal, Mary F. Kearney, John M. Coffin, John W. Mellors
Publikováno v:
Journal of virology. 96(13)
The integration of human immunodeficiency virus type 1 (HIV-1) into chromosomal DNA establishes the long-term persistence of HIV-1 as proviruses despite effective antiretroviral therapy (ART). Characterizing proviruses is difficult because of their r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ae9003ecb75040838546c819ad6341
https://pubmed.ncbi.nlm.nih.gov/35674431
https://pubmed.ncbi.nlm.nih.gov/35674431
Akademický článek
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Autor:
Joshua C. Cyktor, Jason W. Rausch, Wei Shao, Camille Tumiotto, Elias K. Halvas, Michael J. Bale, John W. Mellors, Mary F. Kearney, John M. Coffin, Michele D. Sobolewski, John K. Bui, Jana L. Jacobs, Shuang Guo, Leah D. Brandt, Kevin W. Joseph, Brandon F. Keele, Stephen H. Hughes, Xiaolin Wu, Gene D. Morse
Publikováno v:
J Clin Invest
BACKGROUNDHIV-1 viremia that is not suppressed by combination antiretroviral therapy (ART) is generally attributed to incomplete medication adherence and/or drug resistance. We evaluated individuals referred by clinicians for nonsuppressible viremia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42dce7048535acafa4bed693bf03f41f
https://doi.org/10.1172/jci138099
https://doi.org/10.1172/jci138099
Publikováno v:
Current HIV Research. 18:69-73
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d6dd5a40cddf2829d916b95533622d
https://doi.org/10.2174/1570162x1802200311104204
https://doi.org/10.2174/1570162x1802200311104204