Zobrazeno 1 - 10 of 34 pro vyhledávání: '"W. R. Wragg"'
1
Composition of the antimalarial drug R.63 and the Ing and Manske hydrazine hydrolysis of N-substituted phthalimides
Autor: W. R. Wragg, H. J. Barber
Publikováno v: Nature. 158
DURING 1944, we investigated, as part of our antimalarial research programme, the structure of the potent antimalarial drug R.631. The recent publication by Mosher2 of a further contribution to this subject makes it desirable to report briefly our ow
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907f489f56ae6e855b9b2e2e0213759b
https://pubmed.ncbi.nlm.nih.gov/20999116
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7
The technical preparation of dimidium bromide: A new phenanthridine synthesis
Autor: H. J. Barber, W. R. Wragg, E. M. Eldridge, L. Bretherick, S. J. Holt
Publikováno v: Journal of the Society of Chemical Industry. 69:82-96
In the course of process development for the trypanocidal drug dimidium bromide, a study has been made of the Morgan-Walls phosphoryl chloride cyclintion of 4:4′-dinitro-z-bewmidodi-phenyl to the corresponding pheananthridine. The reaction involves
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::95ff1081b253b89338edd628c1d2c944
https://doi.org/10.1002/jctb.5000690306
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8
Sulphamoylbenzo-1, 2, 3, 4-Thiatriazine 1, 1-Dioxides: A New Class with Oral Diuretic Activity
Autor: W. R. Wragg, G. E. Lee
Publikováno v: Journal of Pharmacy and Pharmacology. 15:589-593
A series of sulphamoylbenzo-1, 2, 3, 4-thiatriazine 1, 1-dioxides has been prepared. While some of them were found to cause diuresis in rats on oral administration, none was more active than chlorothiazide.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e25763e0cf25fd385b425a15f5d91f
https://doi.org/10.1111/j.2042-7158.1963.tb12844.x
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9
Congeners of Pempidine with High Ganglion-blocking Activity
Autor: G. E. Lee, L. Bretherick, N. D. Edge, W. R. Wragg, E. Lunt
Publikováno v: Nature. 184:1707-1709
RESEARCH in these Laboratories on new hypotensive drugs has in recent years centred on the development of compounds exhibiting both a high level of ganglion-blocking activity and good absorption after oral administration. The first phase of this work
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b882d6f9eee6a849abed21bf3c0ec5d
https://doi.org/10.1038/1841707a0
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