Zobrazeno 1 - 10
of 11
pro vyhledávání: '"W. R. Tully"'
Autor:
C. B. Jones, E. A. Kuo, Yea Christopher Martyn, C. J. R. Hedgecock, Peter W. Hairsine, N. Mcdowall, R. A. Williamson, P. Hambleton, W. R. Tully, Robert Westwood, Saroop S. Matharu, Ian R. Ager, David Kay, A. W. E. Chan, P. L. Evans, E. Little
Publikováno v:
Journal of medicinal chemistry. 39(23)
The active metabolite (2) of the novel immunosuppressive agent leflunomide (1) has been shown to inhibit the enzyme dihydroorotate dehydrogenase (DHODH). This enzyme catalyzes the fourth step in de novo pyrimidine biosynthesis. A series of analogues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8746ffa16b541e863c47865210f535c
https://pubmed.ncbi.nlm.nih.gov/8917650
https://pubmed.ncbi.nlm.nih.gov/8917650
Autor:
G. W. Danswan, I. R. Ager, Peter A. Robson, Alan Charles Barnes, Saroop S. Matharu, P. D. Kennewell, D. P. Kay, David Alun Rowlands, P. W. Hairsine, R. Westwolld, P. Miller, W. R. Tully
Publikováno v:
ChemInform. 19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3369738b4a4c91474cfd6bbc6496a17
https://doi.org/10.1002/chin.198843216
https://doi.org/10.1002/chin.198843216
Autor:
S. Clements-Jewery, R. Murdoch, W. R. Tully, Saroop S. Matharu, Robert Westwood, G. W. Danswan, Colin R. Gardner
Publikováno v:
ChemInform. 19
Several series of heterocyclic carboxylic esters were found to be active in the benzodiazepine receptor binding assay, a typical example being ethyl 7-ethyl-5-methoxyimidazo[1,2-a]quinoline-2-carboxylate (4b) with an IC50 of 150 nM. The corresponding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd60ca0e214739f551f83f532a74466d
https://doi.org/10.1002/chin.198843201
https://doi.org/10.1002/chin.198843201
Publikováno v:
ChemInform. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eff10cbf8354899dfb28fc98e82f26cc
https://doi.org/10.1002/chin.198942192
https://doi.org/10.1002/chin.198942192
Autor:
G. W. Danswan, Saroop S. Matharu, S. Clements-Jewery, W. R. Tully, Colin R. Gardner, R. Murdoch, Robert Westwood
Publikováno v:
Journal of medicinal chemistry. 31(6)
Several series of heterocyclic carboxylic esters were found to be active in the benzodiazepine receptor binding assay, a typical example being ethyl 7-ethyl-5-methoxyimidazo[1,2-a]quinoline-2-carboxylate (4b) with an IC50 of 150 nM. The corresponding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24cfb6e6a55120681600262bae2121ad
https://pubmed.ncbi.nlm.nih.gov/2897468
https://pubmed.ncbi.nlm.nih.gov/2897468
Publikováno v:
ChemInform. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3f9d5cf4c4fb0c66668f383dd4f92ee
https://doi.org/10.1002/chin.198702228
https://doi.org/10.1002/chin.198702228
Publikováno v:
Chemischer Informationsdienst. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9f7c8bbbebeb4cd60423fa3ea17e689
https://doi.org/10.1002/chin.198646246
https://doi.org/10.1002/chin.198646246
Autor:
J B, Taylor, W R, Tully
Publikováno v:
Journal of the Chemical Society. Perkin transactions 1. (12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ec7e3fd8743124457271b3ab2e70419
https://pubmed.ncbi.nlm.nih.gov/985819
https://pubmed.ncbi.nlm.nih.gov/985819
Autor:
W. R. Tully, R. M. Acheson
Publikováno v:
Chemischer Informationsdienst. Organische Chemie. 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::807458a7c213034ebd7cc54aec55d48a
https://doi.org/10.1002/chin.197032387
https://doi.org/10.1002/chin.197032387
Autor:
W. R. Tully, R. M. Acheson
Publikováno v:
Journal of the Chemical Society C: Organic. :1117
4-Chloro- and 4,5-dichloro-1,2-phenylenediamines were converted into 1,5-benzodiazepin-2-ones by use of both ethyl acetoacetate and crotonic acid; related diazepinones were obtained by other routes. 4,5-Dichloro-1,2-phenylenediamine, when treated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80be65cfd44f878c80f0eeb2c4e3b61d
https://doi.org/10.1039/j39700001117
https://doi.org/10.1039/j39700001117