Zobrazeno 1 - 10
of 24
pro vyhledávání: '"W. R. Tracey"'
Publikováno v:
Cardiovascular Research. 40:138-145
Objective: The aim of this study was to characterize the adenosine A3 receptor agonist, N 6-(3-chlorobenzyl)-5′- N -methylcarboxamidoadenosine (CB-MECA), evaluate its ability to reduce myocardial ischemia/reperfusion injury and determine the role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d34330b28cdb005bfd8ccdc2083269
https://doi.org/10.1016/s0008-6363(98)00112-6
https://doi.org/10.1016/s0008-6363(98)00112-6
Autor:
Philip A. Marsden, Josiah N. Wilcox, David G. Harrison, Jennifer S. Pollock, Romesh R. Subramanian, C L Sundell, W. R. Tracey
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 17:2479-2488
Abstract Atherosclerosis is associated with reduced endothelium-derived relaxing factor bioactivity. To determine whether this is due to decreased synthesis of nitric oxide synthase (NOS), we examined normal and atherosclerotic human vessels by in si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd057731bf65c401cc987aa7db0cc4a
https://doi.org/10.1161/01.atv.17.11.2479
https://doi.org/10.1161/01.atv.17.11.2479
Publikováno v:
Cardiovascular Research. 36:52-59
Objective: Adenosine receptor activation has been implicated in the mechanism of ischaemic preconditioning protection. Evidence suggests adenosine A1 receptor involvement, and possibly A3 receptor involvement in the rabbit. This study investigated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac031bae94e6c48b0e9c4f340abf8c35
https://doi.org/10.1016/s0008-6363(97)00160-0
https://doi.org/10.1016/s0008-6363(97)00160-0
Publikováno v:
Biochemical and Biophysical Research Communications. 205:659-665
The cerebral microcirculation undergoes specific biochemical changes in Alzheimer's disease. In this study, we have compared the nitric oxide synthase (NOS) activity of brain microvessels isolated from Alzheimer and control brains. L-[3H]-citrulline,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aaec0261b6b332f15798c2fa7230b84
https://doi.org/10.1006/bbrc.1994.2716
https://doi.org/10.1006/bbrc.1994.2716
Autor:
Roger A Johns, Jennifer S. Pollock, U. Forstermann, W. R. Tracey, C. Xue, V. Klinghofer, J. Barlow
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 266:L722-L727
Type II (inducible) nitric oxide synthase (NOS) may play an important role in pulmonary pathophysiology, yet it remains controversial whether human tissues are capable of expressing this protein. Therefore, a polyclonal antibody (8196) was raised aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef85bd2146c40d472a0ce96a14ef4aa3
https://doi.org/10.1152/ajplung.1994.266.6.l722
https://doi.org/10.1152/ajplung.1994.266.6.l722
Publikováno v:
Biochemical and Biophysical Research Communications. 195:1035-1040
NADPH diaphorase activity is used as a histochemical marker for neuronal nitric oxide (NO) synthase; however, it remains unclear whether these activities are directly correlated in all tissues. In N1E-115 neuroblastoma cells, NADPH diaphorase activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::889b9207c6216ee033a6ab5013336ea4
https://doi.org/10.1006/bbrc.1993.2148
https://doi.org/10.1006/bbrc.1993.2148
Autor:
Michael J. Peach, W R Tracey
Publikováno v:
Circulation Research. 70:234-240
Endothelial cells, either in vivo or freshly isolated, respond when exposed to muscarinic agonists with an increase in cytosolic free calcium concentration ([Ca2+]i) and release of endothelium-derived relaxing factor (EDRF). When placed in culture, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449288dedb01a5499d6178447e572976
https://doi.org/10.1161/01.res.70.2.234
https://doi.org/10.1161/01.res.70.2.234
Publikováno v:
American Journal of Physiology-Cell Physiology. 261:C927-C935
The mechanism of phospholipase (PL) C-induced release of endothelium-derived relaxing factor (EDRF) was investigated. Bovine pulmonary artery endothelial cells (BPAEC) were treated with phosphatidylinositol (PI)-selective PLCs, nonselective PLCs, or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c71e253dc260a74d91c8e1f73f4d21ec
https://doi.org/10.1152/ajpcell.1991.261.5.c927
https://doi.org/10.1152/ajpcell.1991.261.5.c927
Autor:
D R, Knight, A H, Smith, D M, Flynn, J T, MacAndrew, S S, Ellery, J X, Kong, R B, Marala, R T, Wester, A, Guzman-Perez, R J, Hill, W P, Magee, W R, Tracey
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 297(1)
The cardioprotective efficacy of zoniporide (CP-597,396), a novel, potent, and selective inhibitor of the sodium-hydrogen exchanger isoform 1 (NHE-1), was evaluated both in vitro and in vivo using rabbit models of myocardial ischemia-reperfusion inju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f62dac7a7e589e47216fde632a12fa3a
https://pubmed.ncbi.nlm.nih.gov/11259552
https://pubmed.ncbi.nlm.nih.gov/11259552
Autor:
R J, Hill, J J, Oleynek, C F, Hoth, M A, Kiron, W, Weng, R T, Wester, W R, Tracey, D R, Knight, R A, Buchholz, S P, Kennedy
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 280(1)
The role of adenosine A1 and A3 receptors in mediating cardioprotection has been studied predominantly in rabbits, yet the pharmacological characteristics of rabbit adenosine A1 and A3 receptor subtypes are unknown. Thus, the rabbit adenosine A3 rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ad8fc091cc2d72ead40cc17f7ec1352
https://pubmed.ncbi.nlm.nih.gov/8996189
https://pubmed.ncbi.nlm.nih.gov/8996189