Zobrazeno 1 - 10
of 39
pro vyhledávání: '"W. R. Levis"'
Publikováno v:
Infection and Immunity. 62:4671-4674
Avirulent mycobacterium H37Ra lipoarabinomannan (LAM) elicited nitric oxide (NO) and tumor necrosis factor alpha in a dose-dependent manner in a murine macrophage cell line, RAW 264.7 cells. H37Ra LAM and recombinant gamma interferon were highly syne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6088ac7e4a18b3d07fe4e69ace354293
https://doi.org/10.1128/iai.62.10.4671-4674.1994
https://doi.org/10.1128/iai.62.10.4671-4674.1994
Publikováno v:
Proceedings of the National Academy of Sciences. 87:973-977
Addition of soluble molecules obtained from sonicated Mycobacterium leprae markedly suppressed the proliferative response to the mitogen anti-CD3 of peripheral blood mononuclear cells and isolated T cells. Suppression was nonspecific and occurred wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8310e81395c84dd67106e7d54b3dcad
https://doi.org/10.1073/pnas.87.3.973
https://doi.org/10.1073/pnas.87.3.973
Publikováno v:
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 69(3)
Pentoxifylline (PTX), a phosphodiesterase inhibitor, is known to downregulate tumor necrosis factor-alpha (TNF-alpha) secretion induced by lipopolysacchride (LPS) and gamma interferon (IFN-gamma). We have had limited success in treating leprosy react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3d12e599426d86baa38720b48f7afe61
https://pubmed.ncbi.nlm.nih.gov/11875767
https://pubmed.ncbi.nlm.nih.gov/11875767
Publikováno v:
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 68(4)
We examined the effects of interferon beta (IFN-beta) on the production of liporabinomannan (LAM)-induced nitric oxide (NO) in peritoneal macrophages from low-responder and high-responder (C3H/HeJ and C3H/OuJ) mice. NO was produced in a dose response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5eda7076ac7bc3cdce2695f052ad052b
https://pubmed.ncbi.nlm.nih.gov/11332287
https://pubmed.ncbi.nlm.nih.gov/11332287
Publikováno v:
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 59(4)
Since antibodies against peripheral nervous system (PNS) antigens may play a pathogenetic role in the mechanism of nerve damage in leprosy, sera from leprosy patients and contacts were investigated for anti-PNS antibodies by ELISA and immunoblot. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::626cbd1a630692bef9e91b378e34296b
https://pubmed.ncbi.nlm.nih.gov/1724981
https://pubmed.ncbi.nlm.nih.gov/1724981
Publikováno v:
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 59(3)
In order to evaluate the potentials of IgA1 versus IgM as well as of native phenolic glycolipid-I (PGL-I) versus PGL-I-disaccharide coupled to bovine serum albumin (D-BSA) as antigens in the serodiagnosis of leprosy, anti-D-BSA IgA1 and anti-PGL-I Ig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2bbfb268027d48eb7120e1efc6f89348
https://pubmed.ncbi.nlm.nih.gov/1890368
https://pubmed.ncbi.nlm.nih.gov/1890368
Publikováno v:
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 58(3)
Sequential serum samples from leprosy patients at various stages of antibacterial treatment were tested by an ELISA for antibodies to phenolic glycolipid I (PGL-I), a synthetic PGL-I analog (ND-BSA), and lipoarabinomannan (LAM) from Mycobacterium tub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::450162fd1ff48b0ac24cf41e52732a4a
https://pubmed.ncbi.nlm.nih.gov/2205685
https://pubmed.ncbi.nlm.nih.gov/2205685
Publikováno v:
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 58(1)
IgG and IgM antibody levels to mycobacterial lipoarabinomannan (LAM) antigen were determined by ELISA in eight sooty mangabey monkeys (Cercocebus atys) prior to and at intervals after experimental inoculation with Mycobacterium leprae. High levels of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::78cc170c3acf6db44ba958fc8baefb5b
https://pubmed.ncbi.nlm.nih.gov/2181045
https://pubmed.ncbi.nlm.nih.gov/2181045
Autor:
Ralph M. Steinman, W R Levis, U Elvers, Gilla Kaplan, M E Patarroyo, Zanvil A. Cohn, D E Weinstein
Publikováno v:
The Journal of Experimental Medicine
In lepromatous leprosy, there is extensive replication of Mycobacterium leprae (M. leprae) within dermal macrophages. This lack of microbial resistance has been attributed to a defective cell-mediated immune response to M. leprae antigens. We have ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa3095a1ae74b5482d384d2979fb721a
https://doi.org/10.1084/jem.162.3.917
https://doi.org/10.1084/jem.162.3.917
Autor:
A Granelli-Piperno, P Kushner, V Colomer Gould, Ralph M. Steinman, Nádia Accioly Pinto Nogueira, L. M. M. Vieira, W R Levis, E Levy, E N Sarno, Gilla Kaplan
Publikováno v:
The Journal of Experimental Medicine
Antigen and mitogen-induced gamma interferon (gamma-IFN) production was studied in peripheral blood mononuclear cells from 34 leprosy patients. 17 of 18 lepromatous leprosy and borderline lepromatous patients (LL and BL) failed to release gamma-IFN i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9276f02df156865008f321b2d4f647e2
https://doi.org/10.1084/jem.158.6.2165
https://doi.org/10.1084/jem.158.6.2165