Výsledky vyhledávání - "W. R. GERRITSEN"

The effects of new life-prolonging drugs for metastatic castration-resistant prostate cancer (mCRPC) patients in a real-world population

Autor: H M, Westgeest, M C P, Kuppen, A J M, van den Eertwegh, R, de Wit, A M, Bergman, R J A, van Moorselaar, J L L M, Coenen, A C M, van den Bergh, D M, Somford, N, Mehra, I M, van Oort, K K H, Aben, W R, Gerritsen, C A, Uyl-de Groot

Publikováno v: Prostate cancer and prostatic diseases. 24(3)

In 2004 docetaxel was the first life-prolonging drug (LPD) registered for metastatic castration-resistant prostate cancer (mCRPC) patients. Between 2011 and 2014 new LPDs for mCRPC (cabazitaxel, abiraterone, enzalutamide, and radium-223) were introdu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::714fe7d207dd872e60a8cbc4144a2c5d
https://pubmed.ncbi.nlm.nih.gov/33746212

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Immunotherapie van kanker

Autor: J. B. A. G. Haanen, W. R. Gerritsen, H. Westdorp

Publikováno v: Leerboek oncologie ISBN: 9789036824484
Leerboek oncologie ISBN: 9789036804417
Leerboek oncologie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d03d035a2b6607ef90da68fccbd11e1
https://doi.org/10.1007/978-90-368-2449-1_11

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Real-world use of radium-223 for treatment of metastatic castration resistant-prostate cancer (mCRPC): Results from the Dutch CAPRI registry

Autor: A.J.M. van den Eertwegh, Katja K.H. Aben, Jules L.L.M. Coenen, W R Gerritsen, Niven Mehra, Jules Lavalaye, J. Van Moorselaar, I.M. van Oort, Andre M. Bergman, H.M. Westgeest, A.C.M. van den Bergh, D.M. Somford, R. de Wit, Malou C.P. Kuppen, C.A. Uyl-de Groot

Publikováno v: Annals of Oncology. 30:v340

Background Radium-223 dichloride (Ra-223) is a targeted alpha-emitter that selectively binds to areas of increased bone turnover in bone metastases. In the ALSYMPCA trial an increased overall survival over placebo in both docetaxel pretreated (14.4 m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c82b566c9b9cf58699fa805d5029e440
https://doi.org/10.1093/annonc/mdz248.026

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Evaluation of Adenoviral Oncolytic Effect on Glioma Spheroids by 18F-DG Positron-Emission Tomography

Autor: Clemens M F Dirven, A. A. Geldof, Martine L.M. Lamfers, Sander Idema, W R Gerritsen, William P. Vandertop, M.A.B. van der Jagt

Publikováno v: Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics. 16:471-477

Multicellular tumor spheroids are used as a model to assess the efficacy of replicating oncolytic adenoviruses. As most assays used to assess cellular viability are unsuitable for oncolytic viruses because of ongoing viral replication, we have used p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0aec31b449dc1cb68438e1ed7a344a32
https://doi.org/10.3727/096504007783338304

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Overexpression of Bcl2 abrogates chemo- and radiotherapy-induced sensitisation of NCI-H460 non-small-cell lung cancer cells to adenovirus-mediated expression of full-length TRAIL

Autor: M A I Abou El Hassan, Frank A.E. Kruyt, W R Gerritsen, Giuseppe Giaccone, D C J Mastenbroek

Publikováno v: British Journal of Cancer, 91(1), 171-7. Nature Publishing Group
British Journal of Cancer
Abou El Hassan, MA, Mastenbroek, DC, Gerritsen, W R, Giaccone, G & Kruyt, F A E 2004, ' Overexpression of Bcl2 abrogates chemo-and radiotherapy-induced sensitisation of NCI-H460 non-small-cell lung cancer cells to adenovirus-mediated expression of full-length TRAIL. ', British Journal of Cancer, vol. 91, no. 1, pp. 171-7 . https://doi.org/10.1038/sj.bjc.6601910

TNF-related apoptosis-inducing ligand (TRAIL, also known as Apo-2L) is a promising novel anticancer agent that selectively induces apoptosis in tumour cells and the activity of which can be enhanced by combined treatment with chemo- or radiotherapy.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497a136a57df820d801cb125546fb70d
https://doi.org/10.1038/sj.bjc.6601910

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Conditionally replicative adenovirus expressing a targeting adapter molecule exhibits enhanced oncolytic potency on CAR-deficient tumors

Autor: P B van den Doel, Martine L.M. Lamfers, H.M. Pinedo, Jacques Grill, T Würdinger, Victor W. van Beusechem, D C J Mastenbroek, W R Gerritsen, Hidde J. Haisma

Publikováno v: van Beusechem, V W, Mastenbroek, D C J, van den Doel, P B, Lamfers, M L M, Grill, J, Würdinger, T, Haisma, H J, Pinedo, H M & Gerritsen, W R 2003, ' Conditionally replicative adenovirus expressing a targeting adapter molecule exhibits enhanced oncolytic potency on CAR-deficient tumors ', Gene Therapy, vol. 10, no. 23, pp. 1982-91 . https://doi.org/10.1038/sj.gt.3302103
Gene Therapy, 10(23), 1982-1991. Nature Publishing Group
Gene Therapy, 10(23), 1982-91. Nature Publishing Group

Conditionally replicative adenoviruses (CRAds) are potentially useful agents for anticancer virotherapy approaches. However, lack of coxsackievirus and adenovirus receptor ( CAR) expression on many primary tumor cells limits the oncolytic potency of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906b63fb8a502b4338e92f72f451eb8a
https://doi.org/10.1038/sj.gt.3302103

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