Zobrazeno 1 - 10
of 13
pro vyhledávání: '"W. R. Christenson"'
Autor:
W. R. Christenson, G.K. Sangha, Claire Croutch, Stephen G. Lake, Larry P. Sheets, Bradley S. Wahle
Publikováno v:
Toxicology. 142:41-56
The chronic toxicology and carcinogenic potential of 1-(1-methyl-propoxycarbonyl)-2-(2-hydroxyethyl)-piperidine (KBR 3023), a prospective new insect repellent intended for human use, was studied in rats using the dermal route of application. Relying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b2e4aafe8de23c54d7b0aa6e4072f2e
https://doi.org/10.1016/s0300-483x(99)00129-8
https://doi.org/10.1016/s0300-483x(99)00129-8
Publikováno v:
Toxicology. 142:29-39
The carcinogenic potential of 1-(1-methyl-propoxycarbonyl)-2-(2-hydroxyethyl)-piperidine (KBR 3023), a prospective new insect repellent intended for human use, was studied in mice using the dermal route of application. Relying upon the toxicology pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd2de05cd35efbe3e2e9d77045808b3
https://doi.org/10.1016/s0300-483x(99)00122-5
https://doi.org/10.1016/s0300-483x(99)00122-5
Autor:
S. N. Shabrang, Michael J. Bartels, Kathy A. Brzak, G. K. Sangha, Debra A. McNett, W. R. Christenson, A. L. Mendrala, C. Timchalk
Publikováno v:
Xenobiotica. 28:579-594
1. Ortho-phenylphenol (OPP) was well absorbed in the male B6C3F1 mouse, with 84 and 98% of the administered radioactivity recovered in the 0-48-h urine of animals administered a single oral dose of 15 or 800 mg/kg respectively. High absorption and ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::904c161c32cc5e7f9ff92d51c3400b06
https://doi.org/10.1080/004982598239335
https://doi.org/10.1080/004982598239335
Publikováno v:
Fundamental and Applied Toxicology. 40:247-255
Tributyl phosphate (TBP) produces tumors of the bladder urothelium in rats at high doses (700 and 3000 ppm), with greater effects in males than in females. TBP does not produce tumors in mice and it is nongenotoxic. The dose response of TBP effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f067dae8e501b3f6f66771d2fef3a9
https://doi.org/10.1006/faat.1997.2391
https://doi.org/10.1006/faat.1997.2391
Publikováno v:
Toxicological Sciences. 40:247-255
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a17d9cb2e068942d1aeac4797d522932
https://doi.org/10.1093/toxsci/40.2.247
https://doi.org/10.1093/toxsci/40.2.247
Autor:
Stephen G. Lake, G.K. Sangha, B. D. Becker, W. R. Christenson, J.H. Thyssen, Barry P. Stuart, P. D. Dass, D. L. Van Goethem, K. D. Moore, Bradley S. Wahle
Publikováno v:
Fundamental and Applied Toxicology. 29:251-259
N -(4-Fluorophenyl)- N -(1-methylethyl)-2-[[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]oxy]acetamide (FOE 5043) is a new acetanilide-type herbicide undergoing regulatory testing. Previous work in this laboratory suggested that FOE 5043-induced reducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f8cceba7bcd768e598a177d5468d8d9
https://doi.org/10.1006/faat.1996.0029
https://doi.org/10.1006/faat.1996.0029
Autor:
H.D. Hoang, B. D. Becker, D.L. Vangoethem, W. R. Christenson, K. D. Moore, J.H. Thyssen, Barry P. Stuart, Stephen G. Lake, G.K. Sangha, Bradley S. Wahle, P. D. Dass
Publikováno v:
Toxicology and Applied Pharmacology. 132:253-262
Evidence of increased hepatic metabolizing capacity coupled with reductions in serum thyroxine (T4) levels were noted in the rat during preliminary toxicity studies with FOE 5043, an oxyacetamide with herbicidal properties. These findings were consis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8c7152519cc98c862dffa70a5598e53
https://doi.org/10.1006/taap.1995.1106
https://doi.org/10.1006/taap.1995.1106
Autor:
P D, Dass, D M, Offutt, M B, Mejia, D, VanGoethem, W R, Christenson, M M, Landes, B P, Stuart, G K, Sangha, J H, Thyssen
Publikováno v:
Veterinary and human toxicology. 39(1)
A kinetic analysis of the substitution of 6,6'-dithiodinicotinic acid (DTNA) for 5,5'-dithiobis-2-nitrobenzoic acid (DTNB) for the determination of rat and human erythrocyte acetylcholinesterase (AChE; EC 3.1.1.7) and plasma butyrylcholinesterase (Bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc8b62dc50cb8301f3172358bb1bd7c8
https://pubmed.ncbi.nlm.nih.gov/9004460
https://pubmed.ncbi.nlm.nih.gov/9004460
Autor:
P D Dass, D L Van Goethem, R S Schroeder, J H Thyssen, G K Sangha, B S Wahle, W R Christenson
Publikováno v:
Toxicology letters. 71(2)
Cholinesterase activity is often a key parameter in the regulatory assessment of cholinesterase-inhibiting agents such as organophosphorous and carbamate pesticides. Thus, the nature and characteristics of the methodology involved in the measurement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5974340a4501f875e6d7c0d7486e98
https://pubmed.ncbi.nlm.nih.gov/8171444
https://pubmed.ncbi.nlm.nih.gov/8171444
Publikováno v:
Archives of Biochemistry and Biophysics. 246:143-148
Altered hepatic microsomal drug metabolism has been reported to occur in afflicted with hyperbilirubinemia. Similarities of the chemical structures of hydroxymethylbilane, an intermediate in the biosynthesis of uroporphyrinogen, to bilirubin prompted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116ce27963a5667534aeba392e1a2d4a
https://doi.org/10.1016/0003-9861(86)90457-1
https://doi.org/10.1016/0003-9861(86)90457-1