Zobrazeno 1 - 10
of 692
pro vyhledávání: '"W. Poole"'
Autor:
Chisato Tsuji, Marston Bradshaw, Megan F. Allen, Molly L. Jackson, Judith Mantell, Ufuk Borucu, Alastair W. Poole, Paul Verkade, Ingeborg Hers, Danielle M. Paul, Mark P. Dodding
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Crosstalk between the actin and microtubule cytoskeletons is important for many cellular processes. Recent studies have shown that microtubules and F-actin can assemble to form a composite structure where F-actin occupies the microtubule lum
Externí odkaz:
https://doaj.org/article/9f1e9987006d4254bcc55c15f45b131c
Autor:
Chisato Tsuji, Marston Bradshaw, Megan F. Allen, Molly L. Jackson, Judith Mantell, Ufuk Borucu, Alastair W. Poole, Paul Verkade, Ingeborg Hers, Danielle M. Paul, Mark P. Dodding
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/8741d6a841cc4a84840e5870077d9241
Autor:
Ejaife O. Agbani, Daniel Young, Si An Chen, Sophie Smith, Adrienne Lee, Alastair W. Poole, Antoine Dufour, Man-Chiu Poon
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-9 (2023)
Abstract Background The Montreal platelet syndrome kindred (MPS) with VWF p.V1316M mutation (2B-VWDMPS) is an extremely rare disorder. It has been associated with macrothrombocytopenia, spontaneous platelet clumping, mucocutaneous, and other bleeding
Externí odkaz:
https://doaj.org/article/57f3e9bbe2d9459d9003041ef4514fd5
Autor:
Xiaojuan Zhao, Dominic Alibhai, Tony G. Walsh, Nathalie Tarassova, Maximilian Englert, Semra Z. Birol, Yong Li, Christopher M. Williams, Chris R. Neal, Philipp Burkard, Stephen J. Cross, Elizabeth W. Aitken, Amie K. Waller, José Ballester Beltrán, Peter W. Gunning, Edna C. Hardeman, Ejaife O. Agbani, Bernhard Nieswandt, Ingeborg Hers, Cedric Ghevaert, Alastair W. Poole
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Platelets, small hemostatic blood cells, are derived from megakaryocytes. Both bone marrow and lung are principal sites of thrombopoiesis although underlying mechanisms remain unclear. Outside the body, however, our ability to generate large
Externí odkaz:
https://doaj.org/article/b34379c46b594e3991173e9d3c71b0ac
Autor:
Ejaife O. Agbani, Alastair W. Poole
Publikováno v:
Platelets, Vol 32, Iss 7, Pp 895-901 (2021)
Structurally, aquaporins (AQPs) are small channel proteins with monomers of ~ 30 kDa that are assembled as tetramers to form pores on cell membranes. Aquaporins mediate the conduction of water but at times also small solutes including glycerol across
Externí odkaz:
https://doaj.org/article/4d26d1762cd146438d487ab805a515fa
Autor:
Ejaife O. Agbani, Xiaojuan Zhao, Christopher M. Williams, Riyaad Aungraheeta, Ingeborg Hers, Erik R. Swenson, Alastair W. Poole
Publikováno v:
Platelets, Vol 31, Iss 7, Pp 853-859 (2020)
Carbonic anhydrase (CA) inhibitors have a long history of safe clinical use as mild diuretics, in the treatment of glaucoma and for altitude sickness prevention. In this study, we aimed to determine if CA inhibition may be an alternative approach to
Externí odkaz:
https://doaj.org/article/11445fa9127a4fe7970911cc098ae65b
Autor:
Lucy J. Goudswaard, Christopher M. Williams, Jawad Khalil, Kate L. Burley, Fergus Hamilton, David Arnold, Alice Milne, Phil A. Lewis, Kate J. Heesom, Stuart J. Mundell, Andrew D. Davidson, Alastair W. Poole, Ingeborg Hers
Publikováno v:
Journal of Thrombosis and Haemostasis. 21:1307-1321
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b27cf07626c81d8658f3b79631aa5fb
https://doi.org/10.1016/j.jtha.2023.01.018
https://doi.org/10.1016/j.jtha.2023.01.018
Autor:
Justin S. Trory, Attila Munkacsi, Kamila M. Śledź, Jordan Vautrinot, Lucy J. Goudswaard, Molly L. Jackson, Kate J. Heesom, Samantha F. Moore, Alastair W. Poole, Behnam Nabet, Varinder K. Aggarwal, Ingeborg Hers
Publikováno v:
Blood Advances. 7:1692-1696
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::421bf9bb63dacbac2589496b3688dce5
https://doi.org/10.1182/bloodadvances.2022008466
https://doi.org/10.1182/bloodadvances.2022008466
Publikováno v:
Blood Advances. 7:1615-1619
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f22eb7139754cdf54cd36bf736fa31
https://doi.org/10.1182/bloodadvances.2022008122
https://doi.org/10.1182/bloodadvances.2022008122
Publikováno v:
Platelets, Vol 30, Iss 1, Pp 31-40 (2019)
Our understanding of fundamental biological processes within platelets is continually evolving. A critical feature of platelet biology relates to the intricate uptake, packaging and release of bioactive cargo from storage vesicles, essential in media
Externí odkaz:
https://doaj.org/article/e25abd86e7754e8b84be14d26bacd97d