Zobrazeno 1 - 9
of 9
pro vyhledávání: '"W. P. McNally"'
Autor:
W P, McNally, W F, Pool, M W, Sinz, P, Dehart, D F, Ortwine, C C, Huang, T, Chang, T F, Woolf
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 24(6)
Tacrine [1,2,3,4-tetrahydro-9-acridinamine monohydrochloride monohydrate (THA), Cognex] is a potent acetylcholinesterase inhibitor recently approved for treatment of mild-to-moderate Alzheimer's disease. The potential for THA and/or a metabolite of T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::414a189df1f28810b65909e7d5e27264
https://pubmed.ncbi.nlm.nih.gov/8781777
https://pubmed.ncbi.nlm.nih.gov/8781777
Autor:
L L, Radulovic, D, Türck, A, von Hodenberg, K O, Vollmer, W P, McNally, P D, DeHart, B J, Hanson, H N, Bockbrader, T, Chang
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 23(4)
Gabapentin, an analog of gamma-aminobutyric acid, exhibits anticonvulsant properties in both animal models and humans. Gabapentin pharmacokinetics was studied in laboratory animals using HPLC and radiometry. Oral bioavailability was 40% in monkeys ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0101006a48980bad24b1192cc0b31cca
https://pubmed.ncbi.nlm.nih.gov/7600909
https://pubmed.ncbi.nlm.nih.gov/7600909
Autor:
Prantika Som, Dale G. Deutsch, Omanand Koul, Yoshiharu Yonekura, Irwin Fand, W. P. McNally, A. Bertrand Brill
Publikováno v:
Toxicology and Applied Pharmacology. 93:421-432
When evaluated by whole-body autoradiography (WBAR) and quantitative densitometry, [ 3 H]phencyclidine (PCP) equivalents were found to be removed rapidly from blood, after a single iv dose in mice, and avidly taken up as early as 1 min after dosage b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d1893b6a8bff4e131e6c69f8a256de
https://doi.org/10.1016/0041-008x(88)90045-2
https://doi.org/10.1016/0041-008x(88)90045-2
Autor:
I, Fand, R M, Sharkey, W P, McNally, A B, Brill, P, Som, K, Yamamoto, F J, Primus, D M, Goldenberg
Publikováno v:
Cancer research. 46(1)
Quantitative whole-body autoradiography (WBAR) was used to study the biodistribution of goat anti-carcinoembryonic antigen and normal goat IgG, each labeled with 125I, in hamsters bearing the carcinoembryonic antigen-producing GW-39 human colonic car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1406a5eeef206e8a242f02e255669f1
https://pubmed.ncbi.nlm.nih.gov/3940196
https://pubmed.ncbi.nlm.nih.gov/3940196
Publikováno v:
Neurotoxicology. 7(1)
The susceptibility of adult neural tissues to the detrimental effects of Pb poisoning has prompted the present distributional analysis of lead in the brains of chronically lead-exposed mice. A high-resolution microPIXE method was developed for measur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60358dcab7fdcf003c1a6ed49f3a4463
https://pubmed.ncbi.nlm.nih.gov/3714129
https://pubmed.ncbi.nlm.nih.gov/3714129
Autor:
I, Fand, W P, McNally
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 250(1)
The whole-body localization of dl-alpha-[3, 4-14C2]-tocopheryl acetate was examined in the rat for intervals ranging between 12-96 hr following administration of a single oral dose. Quantitative evaluation of the macroautoradiograms revealed a rapid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba9f3851de05704be7d6b57406074184
https://pubmed.ncbi.nlm.nih.gov/7271380
https://pubmed.ncbi.nlm.nih.gov/7271380
Publikováno v:
Cancer research. 42(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32b6b842da3cce2469269b021219660a
https://pubmed.ncbi.nlm.nih.gov/7139615
https://pubmed.ncbi.nlm.nih.gov/7139615
Autor:
R G, Fairchild, D, Greenberg, K P, Watts, S, Packer, H L, Atkins, P, Som, S J, Hannon, A B, Brill, I, Fand, W P, McNally
Publikováno v:
Cancer research. 42(2)
Chlorpromazine (CPZ) distribution was measured in tissues of Syrian golden hamsters bearing Greene melanoma and in BALB/c mice bearing Harding-Passey melanoma. Distribution was evaluated as a function of time (0.5 to 14 days) and as a function of sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::541c219c5387009d8bd734310c9da09b
https://pubmed.ncbi.nlm.nih.gov/7055803
https://pubmed.ncbi.nlm.nih.gov/7055803
Publikováno v:
Fresenius' Zeitschrift für analytische Chemie. 326:742-743
Until recently no techniques which have multielement detection capability, high sensitivity and good spatial resolution in relatively thick tissue section have existed. The use of proton induced x-ray emission (PIXE) and synchrotron radiation induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed02dce7582af1841ad60861bc12c889
https://doi.org/10.1007/bf00473545
https://doi.org/10.1007/bf00473545