Zobrazeno 1 - 10
of 18
pro vyhledávání: '"W. P. Dole"'
Publikováno v:
Journal of hypertension. 12(2)
In previous studies severe, acute hypertension damaged the endothelium in proximal coronary arteries and selectively potentiated constriction of the artery to serotonin. In the present study we investigated the role of several mechanical factors and
Publikováno v:
The Journal of rheumatology. 19(9)
We conducted this study to assess the clinical usefulness and physiologic effects of intravenous iloprost in patients with Raynaud's phenomenon secondary to systemic sclerosis.Thirty-five patients with Raynaud's phenomenon secondary to systemic scler
Publikováno v:
Agents and actions. Supplements. 37
The inhibition of platelet aggregation during cardiopulmonary bypass and effects on post-operative placebo-controlled study of 145 patients. Significant preservation of platelet numbers and function were shown without significant haemodynamic problem
Publikováno v:
The American journal of medicine. 90(5)
Patients with systemic sclerosis (SSc) do not exhibit a normal increase in the diffusing capacity for carbon monoxide (DLCO) on assuming the supine position. We sought to determine whether a potent prostacyclin derivative and vasodilator, iloprost, w
Publikováno v:
Circulation research. 66(6)
We examined the relative contribution of endothelial and vascular smooth muscle-derived prostaglandins and endothelium-derived relaxing factor in modulating both the large coronary artery and resistance vessel responses to thromboxane in vivo. Vascul
Autor:
H.-L. A. Huang, S. Vaidyanathan, C.-M. Yeh, M.-N. Bizot, H. A. Dieterich, W. P. Dole, D. Howard
Publikováno v:
Current Medical Research & Opinion; Sep2008, Vol. 24 Issue 9, p2449-2456, 8p
Autor:
W P Dole, Kathryn G. Lamping
Publikováno v:
Circulation Research. 61:904-913
We tested the hypothesis that acute coronary artery hypertension may damage vascular endothelium and alter vasomotor responses to humoral agents. We examined effects of intracoronary infusion of the endothelium-dependent agent serotonin and two endot
Publikováno v:
Medical & Biological Engineering & Computing. 25:420-427
Although present sonomicrometer techniques for measuring continuous changes in vascular diameter are very useful, two problems with available methods are difficulty in maintaining crystal alignment throughout an acute experiment and inability to meas
Autor:
W P Dole, V S Bishop
Publikováno v:
Circulation Research. 50:377-385
Publikováno v:
Circulation Research. 56:517-524
We employed intracoronary infusion of adenosine deaminase to test the hypothesis that endogenous adenosine contributes to regulation of coronary blood flow following acute reductions in coronary artery pressure. In 16 closed-chest anesthetized dogs,